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Journal Abstract Search


170 related items for PubMed ID: 19429821

  • 1. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity.
    Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF.
    Am J Physiol Heart Circ Physiol; 2009 Jul; 297(1):H181-90. PubMed ID: 19429821
    [Abstract] [Full Text] [Related]

  • 2. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis.
    Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga GM, Solaro RJ, Liggett SB, Wieczorek DF.
    Am J Physiol Heart Circ Physiol; 2007 Aug; 293(2):H949-58. PubMed ID: 17416600
    [Abstract] [Full Text] [Related]

  • 3. Functional importance of the carboxyl-terminal region of striated muscle tropomyosin.
    Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Vahebi S, DeTombe P, Solaro RJ, Labitzke E, Hilliard G, Wieczorek DF.
    J Biol Chem; 2003 Jun 20; 278(25):23204-11. PubMed ID: 12690096
    [Abstract] [Full Text] [Related]

  • 4. Physiological significance of troponin T binding domains in striated muscle tropomyosin.
    Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga G, de Tombe PP, Solaro RJ, Wieczorek DF.
    Am J Physiol Heart Circ Physiol; 2004 Oct 20; 287(4):H1484-94. PubMed ID: 15191887
    [Abstract] [Full Text] [Related]

  • 5. Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity.
    Jagatheesan G, Rajan S, Ahmed RP, Petrashevskaya N, Boivin G, Arteaga GM, Tae HJ, Liggett SB, Solaro RJ, Wieczorek DF.
    J Muscle Res Cell Motil; 2010 Sep 20; 31(3):227-39. PubMed ID: 20803058
    [Abstract] [Full Text] [Related]

  • 6. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
    Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF.
    Circ Res; 2007 Jul 20; 101(2):205-14. PubMed ID: 17556658
    [Abstract] [Full Text] [Related]

  • 7. Changes in end-to-end interactions of tropomyosin affect mouse cardiac muscle dynamics.
    Gaffin RD, Gokulan K, Sacchettini JC, Hewett TE, Klevitsky R, Robbins J, Sarin V, Zawieja DC, Meininger GA, Muthuchamy M.
    Am J Physiol Heart Circ Physiol; 2006 Aug 20; 291(2):H552-63. PubMed ID: 16501024
    [Abstract] [Full Text] [Related]

  • 8. Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin.
    Wolska BM, Keller RS, Evans CC, Palmiter KA, Phillips RM, Muthuchamy M, Oehlenschlager J, Wieczorek DF, de Tombe PP, Solaro RJ.
    Circ Res; 1999 Apr 16; 84(7):745-51. PubMed ID: 10205142
    [Abstract] [Full Text] [Related]

  • 9. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation.
    Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF.
    Am J Physiol Heart Circ Physiol; 2002 Oct 16; 283(4):H1344-53. PubMed ID: 12234784
    [Abstract] [Full Text] [Related]

  • 10. Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy.
    Evans CC, Pena JR, Phillips RM, Muthuchamy M, Wieczorek DF, Solaro RJ, Wolska BM.
    Am J Physiol Heart Circ Physiol; 2000 Nov 16; 279(5):H2414-23. PubMed ID: 11045979
    [Abstract] [Full Text] [Related]

  • 11. Charged residue changes in the carboxy-terminus of alpha-tropomyosin alter mouse cardiac muscle contractility.
    Gaffin RD, Gokulan K, Sacchettini JC, Hewett T, Klevitsky R, Robbins J, Muthuchamy M.
    J Physiol; 2004 Apr 15; 556(Pt 2):531-43. PubMed ID: 14766940
    [Abstract] [Full Text] [Related]

  • 12. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation.
    Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ.
    J Muscle Res Cell Motil; 2011 Mar 15; 31(5-6):315-22. PubMed ID: 21221740
    [Abstract] [Full Text] [Related]

  • 13. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L.
    Yar S, Chowdhury SAK, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ.
    J Biol Chem; 2013 Jun 07; 288(23):16235-16246. PubMed ID: 23609439
    [Abstract] [Full Text] [Related]

  • 14. The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.
    Lynn ML, Tal Grinspan L, Holeman TA, Jimenez J, Strom J, Tardiff JC.
    J Mol Cell Cardiol; 2017 Jul 07; 108():127-137. PubMed ID: 28600229
    [Abstract] [Full Text] [Related]

  • 15. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform.
    Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF.
    Circulation; 2010 Jan 26; 121(3):410-8. PubMed ID: 20065163
    [Abstract] [Full Text] [Related]

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  • 17. Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase.
    Sirenko SG, Potter JD, Knollmann BC.
    J Physiol; 2006 Aug 15; 575(Pt 1):201-13. PubMed ID: 16777946
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  • 20. Interplay between the overlapping ends of tropomyosin and the N terminus of cardiac troponin T affects tropomyosin states on actin.
    Mamidi R, Michael JJ, Muthuchamy M, Chandra M.
    FASEB J; 2013 Sep 15; 27(9):3848-59. PubMed ID: 23748972
    [Abstract] [Full Text] [Related]


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