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237 related items for PubMed ID: 19430535

  • 1. Pivotal role of the alpha(2A)-adrenoceptor in producing inflammation and organ injury in a rat model of sepsis.
    Miksa M, Das P, Zhou M, Wu R, Dong W, Ji Y, Goyert SM, Ravikumar TS, Wang P.
    PLoS One; 2009; 4(5):e5504. PubMed ID: 19430535
    [Abstract] [Full Text] [Related]

  • 2. Antagonism of alpha2A-adrenoceptor: a novel approach to inhibit inflammatory responses in sepsis.
    Zhang F, Wu R, Qiang X, Zhou M, Wang P.
    J Mol Med (Berl); 2010 Mar; 88(3):289-96. PubMed ID: 19894027
    [Abstract] [Full Text] [Related]

  • 3. Alpha 2A-adrenoreceptor blockade improves sepsis-induced acute lung injury accompanied with depressed high mobility group box-1 levels in rats.
    Ji MH, Zhu XL, Liu FF, Li GM, Tian M, Wu J, Fan YX, Li N, Yang JJ.
    Cytokine; 2012 Dec; 60(3):639-45. PubMed ID: 22959885
    [Abstract] [Full Text] [Related]

  • 4. The role of Kupffer cell alpha(2)-adrenoceptors in norepinephrine-induced TNF-alpha production.
    Zhou M, Yang S, Koo DJ, Ornan DA, Chaudry IH, Wang P.
    Biochim Biophys Acta; 2001 Jul 27; 1537(1):49-57. PubMed ID: 11476962
    [Abstract] [Full Text] [Related]

  • 5. Norepinephrine-induced hepatocellular dysfunction in early sepsis is mediated by activation of alpha2-adrenoceptors.
    Yang S, Zhou M, Chaudry IH, Wang P.
    Am J Physiol Gastrointest Liver Physiol; 2001 Oct 27; 281(4):G1014-21. PubMed ID: 11557522
    [Abstract] [Full Text] [Related]

  • 6. α2A -AR antagonism by BRL-44408 maleate attenuates acute lung injury in rats with downregulation of ERK1/2, p38MAPK, and p65 pathway.
    Cong Z, Li D, Tao Y, Lv X, Zhu X.
    J Cell Physiol; 2020 Oct 27; 235(10):6905-6914. PubMed ID: 32003020
    [Abstract] [Full Text] [Related]

  • 7. α₁ adrenoceptor activation by norepinephrine inhibits LPS-induced cardiomyocyte TNF-α production via modulating ERK1/2 and NF-κB pathway.
    Yu X, Jia B, Wang F, Lv X, Peng X, Wang Y, Li H, Wang Y, Lu D, Wang H.
    J Cell Mol Med; 2014 Feb 27; 18(2):263-73. PubMed ID: 24304472
    [Abstract] [Full Text] [Related]

  • 8. Upregulation of Kupffer cell α2A-Adrenoceptors and downregulation of MKP-1 mediate hepatic injury in chronic alcohol exposure.
    Ajakaiye MA, Jacob A, Wu R, Zhou M, Ji Y, Dong W, Wang Z, Qiang X, Chaung WW, Nicastro J, Coppa GF, Wang P.
    Biochem Biophys Res Commun; 2011 Jun 10; 409(3):406-11. PubMed ID: 21575605
    [Abstract] [Full Text] [Related]

  • 9. Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages.
    Wang YY, Dahle MK, Steffensen KR, Reinholt FP, Collins JL, Thiemermann C, Aasen AO, Gustafsson JA, Wang JE.
    Shock; 2009 Nov 10; 32(5):548-53. PubMed ID: 19295476
    [Abstract] [Full Text] [Related]

  • 10. [BRL-44408 maleate, the antagonist of α2A-adrenoceptor, attenuates endogenous lipopolysacchride-induced acute lung injury through inhibiting the mitogen-activated protein kinase kinase/extracellular regulated protein kinases signaling pathway in mice].
    Lyu X, Cong Z, Tao Y, Li D, Zhu X.
    Zhonghua Wei Zhong Bing Ji Jiu Yi Xue; 2018 Feb 10; 30(2):101-106. PubMed ID: 29402356
    [Abstract] [Full Text] [Related]

  • 11. α2A-adrenergic blockade attenuates septic cardiomyopathy by increasing cardiac norepinephrine concentration and inhibiting cardiac endothelial activation.
    Yu X, Wang Y, Yang D, Tang X, Li H, Lv X, Qi R, Hu C, Lu D, Lv B, Wang H.
    Sci Rep; 2018 Apr 03; 8(1):5478. PubMed ID: 29615637
    [Abstract] [Full Text] [Related]

  • 12. Endotoxin downregulates peroxisome proliferator-activated receptor-gamma via the increase in TNF-alpha release.
    Zhou M, Wu R, Dong W, Jacob A, Wang P.
    Am J Physiol Regul Integr Comp Physiol; 2008 Jan 03; 294(1):R84-92. PubMed ID: 17989144
    [Abstract] [Full Text] [Related]

  • 13. Benznidazole treatment attenuates liver NF-κB activity and MAPK in a cecal ligation and puncture model of sepsis.
    Ronco MT, Manarin R, Francés D, Serra E, Revelli S, Carnovale C.
    Mol Immunol; 2011 Mar 03; 48(6-7):867-73. PubMed ID: 21269697
    [Abstract] [Full Text] [Related]

  • 14. [Role of p38MAPK signal transduction pathway in Kupffer cells production of TNF-alpha and IL-1beta in severely burned rats].
    Chen XL, Xia ZF, Wei D, Ben DF, Wang YJ.
    Zhonghua Wai Ke Za Zhi; 2005 Feb 01; 43(3):185-8. PubMed ID: 15842901
    [Abstract] [Full Text] [Related]

  • 15. The inhibitory effect of ghrelin on sepsis-induced inflammation is mediated by the MAPK phosphatase-1.
    Jacob A, Rajan D, Pathickal B, Balouch I, Hartman A, Wu R, Zhou M, Wang P.
    Int J Mol Med; 2010 Jan 01; 25(1):159-64. PubMed ID: 19956915
    [Abstract] [Full Text] [Related]

  • 16. Ghrelin inhibits sympathetic nervous activity in sepsis.
    Wu R, Zhou M, Das P, Dong W, Ji Y, Yang D, Miksa M, Zhang F, Ravikumar TS, Wang P.
    Am J Physiol Endocrinol Metab; 2007 Dec 01; 293(6):E1697-702. PubMed ID: 17911350
    [Abstract] [Full Text] [Related]

  • 17. Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries.
    Chotani MA, Flavahan S, Mitra S, Daunt D, Flavahan NA.
    Am J Physiol Heart Circ Physiol; 2000 Apr 01; 278(4):H1075-83. PubMed ID: 10749700
    [Abstract] [Full Text] [Related]

  • 18. Ketamine inhibits LPS-induced HGMB1 release in vitro and in vivo.
    Zhang Z, Zhang L, Zhou C, Wu H.
    Int Immunopharmacol; 2014 Nov 01; 23(1):14-26. PubMed ID: 25133650
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of hepatocellular dysfunction during early sepsis. Key role of increased gene expression and release of proinflammatory cytokines tumor necrosis factor and interleukin-6.
    Wang P, Ba ZF, Chaudry IH.
    Arch Surg; 1997 Apr 01; 132(4):364-9; discussion 369-70. PubMed ID: 9108756
    [Abstract] [Full Text] [Related]

  • 20. Yohimbine promotes cardiac NE release and prevents LPS-induced cardiac dysfunction via blockade of presynaptic α2A-adrenergic receptor.
    Wang Y, Yu X, Wang F, Wang Y, Wang Y, Li H, Lv X, Lu D, Wang H.
    PLoS One; 2013 Apr 01; 8(5):e63622. PubMed ID: 23691077
    [Abstract] [Full Text] [Related]


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