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Journal Abstract Search

177 related items for PubMed ID: 19433358

  • 1. Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands.
    Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ.
    Bioorg Med Chem Lett; 2009 Jun 15; 19(12):3214-6. PubMed ID: 19433358
    [Abstract] [Full Text] [Related]

  • 2. 1-Sulfonylindazoles as potent and selective 5-HT6 ligands.
    Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ.
    Bioorg Med Chem Lett; 2009 May 01; 19(9):2413-5. PubMed ID: 19345582
    [Abstract] [Full Text] [Related]

  • 3. Identification of a series of benzoxazoles as potent 5-HT6 ligands.
    Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ.
    Bioorg Med Chem Lett; 2009 Feb 15; 19(4):1115-7. PubMed ID: 19152787
    [Abstract] [Full Text] [Related]

  • 4. Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists.
    Liu KG, Robichaud AJ, Greenfield AA, Lo JR, Grosanu C, Mattes JF, Cai Y, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Comery TA.
    Bioorg Med Chem; 2011 Jan 01; 19(1):650-62. PubMed ID: 21093272
    [Abstract] [Full Text] [Related]

  • 5. 5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists.
    Liu KG, Robichaud AJ, Bernotas RC, Yan Y, Lo JR, Zhang MY, Hughes ZA, Huselton C, Zhang GM, Zhang JY, Kowal DM, Smith DL, Schechter LE, Comery TA.
    J Med Chem; 2010 Nov 11; 53(21):7639-46. PubMed ID: 20932009
    [Abstract] [Full Text] [Related]

  • 6. 5-HT6 receptor antagonists: prospects for the treatment of cognitive disorders including dementia.
    Johnson CN, Ahmed M, Miller ND.
    Curr Opin Drug Discov Devel; 2008 Sep 11; 11(5):642-54. PubMed ID: 18729016
    [Abstract] [Full Text] [Related]

  • 7. Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.
    Holenz J, Mercè R, Díaz JL, Guitart X, Codony X, Dordal A, Romero G, Torrens A, Mas J, Andaluz B, Hernández S, Monroy X, Sánchez E, Hernández E, Pérez R, Cubí R, Sanfeliu O, Buschmann H.
    J Med Chem; 2005 Mar 24; 48(6):1781-95. PubMed ID: 15771424
    [Abstract] [Full Text] [Related]

  • 8. The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease.
    Geldenhuys WJ, Van der Schyf CJ.
    Expert Rev Neurother; 2009 Jul 24; 9(7):1073-85. PubMed ID: 19589055
    [Abstract] [Full Text] [Related]

  • 9. Cognitive dysfunction in neuropsychiatric disorders: selected serotonin receptor subtypes as therapeutic targets.
    Terry AV, Buccafusco JJ, Wilson C.
    Behav Brain Res; 2008 Dec 16; 195(1):30-8. PubMed ID: 18241938
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of novel gamma-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists.
    Ivachtchenko AV, Frolov EB, Mitkin OD, Kysil VM, Khvat AV, Okun IM, Tkachenko SE.
    Bioorg Med Chem Lett; 2009 Jun 15; 19(12):3183-7. PubMed ID: 19443217
    [Abstract] [Full Text] [Related]

  • 11. Actions of novel agonists, antagonists and antipsychotic agents at recombinant rat 5-HT6 receptors: a comparative study of coupling to G alpha s.
    Dupuis DS, Mannoury la Cour C, Chaput C, Verrièle L, Lavielle G, Millan MJ.
    Eur J Pharmacol; 2008 Jul 07; 588(2-3):170-7. PubMed ID: 18511034
    [Abstract] [Full Text] [Related]

  • 12. 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives as 5-HT6 receptor antagonists.
    Zhao SH, Berger J, Clark RD, Sethofer SG, Krauss NE, Brothers JM, Martin RS, Misner DL, Schwab D, Alexandrova L.
    Bioorg Med Chem Lett; 2007 Jun 15; 17(12):3504-7. PubMed ID: 17485206
    [Abstract] [Full Text] [Related]

  • 13. 5-HT6 receptors: a novel target for cognitive enhancement.
    Mitchell ES, Neumaier JF.
    Pharmacol Ther; 2005 Dec 15; 108(3):320-33. PubMed ID: 16005519
    [Abstract] [Full Text] [Related]

  • 14. 5-HT6 receptor antagonists as potential therapeutics for cognitive impairment.
    Rossé G, Schaffhauser H.
    Curr Top Med Chem; 2010 Dec 15; 10(2):207-21. PubMed ID: 20166958
    [Abstract] [Full Text] [Related]

  • 15. Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists.
    Elokdah H, Li D, McFarlane G, Bernotas RC, Robichaud AJ, Magolda RL, Zhang GM, Smith D, Schechter LE.
    Bioorg Med Chem; 2007 Sep 15; 15(18):6208-26. PubMed ID: 17624788
    [Abstract] [Full Text] [Related]

  • 16. [Synthesis and biological activities of new 5-HT2A selective ligands--N-substituted-piperidinyl-4-phenylthioether and sulfone derivatives].
    Wang H, Wen R, Huang L, Bi R, Tan PZ.
    Yao Xue Xue Bao; 2001 Apr 15; 36(4):274-7. PubMed ID: 12580055
    [Abstract] [Full Text] [Related]

  • 17. Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists.
    Holmberg P, Sohn D, Leideborg R, Caldirola P, Zlatoidsky P, Hanson S, Mohell N, Rosqvist S, Nordvall G, Johansson AM, Johansson R.
    J Med Chem; 2004 Jul 29; 47(16):3927-30. PubMed ID: 15267230
    [Abstract] [Full Text] [Related]

  • 18. The procognitive effects of 5-HT6 receptor ligands in animal models of schizophrenia.
    Nikiforuk A.
    Rev Neurosci; 2014 Jul 29; 25(3):367-82. PubMed ID: 24501158
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT6 receptor antagonists.
    Ivachtchenko AV, Dmitriev DE, Golovina ES, Dubrovskaya ES, Kadieva MG, Koryakova AG, Kysil VM, Mitkin OD, Tkachenko SE, Okun IM, Vorobiov AA.
    Bioorg Med Chem Lett; 2010 Apr 01; 20(7):2133-6. PubMed ID: 20207539
    [Abstract] [Full Text] [Related]

  • 20. 5-HT(6) receptor and cognition.
    Codony X, Vela JM, Ramírez MJ.
    Curr Opin Pharmacol; 2011 Feb 01; 11(1):94-100. PubMed ID: 21330210
    [Abstract] [Full Text] [Related]

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