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261 related items for PubMed ID: 19439470
1. Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase. Laguette N, Brégnard C, Bouchet J, Benmerah A, Benichou S, Basmaciogullari S. J Virol; 2009 Jul; 83(14):7117-28. PubMed ID: 19439470 [Abstract] [Full Text] [Related]
2. HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes. Kim YH, Chang SH, Kwon JH, Rhee SS. Virology; 1999 Apr 25; 257(1):208-19. PubMed ID: 10208934 [Abstract] [Full Text] [Related]
3. Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail. Salghetti S, Mariani R, Skowronski J. Proc Natl Acad Sci U S A; 1995 Jan 17; 92(2):349-53. PubMed ID: 7831289 [Abstract] [Full Text] [Related]
4. HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4. Bandres JC, Shaw AS, Ratner L. Virology; 1995 Feb 20; 207(1):338-41. PubMed ID: 7871751 [Abstract] [Full Text] [Related]
5. Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. Rhee SS, Marsh JW. J Virol; 1994 Aug 20; 68(8):5156-63. PubMed ID: 8035515 [Abstract] [Full Text] [Related]
6. The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef. Anderson SJ, Lenburg M, Landau NR, Garcia JV. J Virol; 1994 May 20; 68(5):3092-101. PubMed ID: 8151774 [Abstract] [Full Text] [Related]
7. Multifunctional Roles of the N-Terminal Region of HIV-1SF2Nef Are Mediated by Three Independent Protein Interaction Sites. Ananth S, Morath K, Trautz B, Tibroni N, Shytaj IL, Obermaier B, Stolp B, Lusic M, Fackler OT. J Virol; 2019 Dec 12; 94(1):. PubMed ID: 31597760 [Abstract] [Full Text] [Related]
8. HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling. Pan X, Rudolph JM, Abraham L, Habermann A, Haller C, Krijnse-Locker J, Fackler OT. Blood; 2012 Jan 19; 119(3):786-97. PubMed ID: 22123847 [Abstract] [Full Text] [Related]
9. Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef. Chase AJ, Wombacher R, Fackler OT. J Biol Chem; 2018 May 18; 293(20):7824-7840. PubMed ID: 29588370 [Abstract] [Full Text] [Related]
10. Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions. Bouchet J, Hérate C, Guenzel CA, Vérollet C, Järviluoma A, Mazzolini J, Rafie S, Chames P, Baty D, Saksela K, Niedergang F, Maridonneau-Parini I, Benichou S. J Virol; 2012 May 18; 86(9):4856-67. PubMed ID: 22345475 [Abstract] [Full Text] [Related]
11. HIV-1 Nef disrupts maturation of CD4+ T cells through CD4/Lck modulation. Chrobak P, Simard MC, Bouchard N, Ndolo TM, Guertin J, Hanna Z, Dave V, Jolicoeur P. J Immunol; 2010 Oct 01; 185(7):3948-59. PubMed ID: 20826747 [Abstract] [Full Text] [Related]
12. Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor. Amorim NA, da Silva EM, de Castro RO, da Silva-Januário ME, Mendonça LM, Bonifacino JS, da Costa LJ, daSilva LL. J Biol Chem; 2014 Oct 03; 289(40):27744-56. PubMed ID: 25118280 [Abstract] [Full Text] [Related]
13. An Amino Acid Polymorphism within the HIV-1 Nef Dileucine Motif Functionally Uncouples Cell Surface CD4 and SERINC5 Downregulation. Mumby MJ, Johnson AL, Trothen SM, Edgar CR, Gibson R, Stathopulos PB, Arts EJ, Dikeakos JD. J Virol; 2021 Jul 26; 95(16):e0058821. PubMed ID: 34037423 [Abstract] [Full Text] [Related]
14. Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines. Greenway A, Azad A, McPhee D. J Virol; 1995 Mar 26; 69(3):1842-50. PubMed ID: 7853525 [Abstract] [Full Text] [Related]
15. Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef. Gratton S, Yao XJ, Venkatesan S, Cohen EA, Sékaly RP. J Immunol; 1996 Oct 15; 157(8):3305-11. PubMed ID: 8871625 [Abstract] [Full Text] [Related]
16. Lack of p56lck expression correlates with CD4 endocytosis in primary lymphoid and myeloid cells. Pelchen-Matthews A, da Silva RP, Bijlmakers MJ, Signoret N, Gordon S, Marsh M. Eur J Immunol; 1998 Nov 15; 28(11):3639-47. PubMed ID: 9842906 [Abstract] [Full Text] [Related]
17. The human immunodeficiency virus (HIV) Rev-binding protein (HRB) is a co-factor for HIV-1 Nef-mediated CD4 downregulation. Landi A, Timermans CG, Naessens E, Vanderstraeten H, Stove V, Verhasselt B. J Gen Virol; 2016 Mar 15; 97(3):778-785. PubMed ID: 26701340 [Abstract] [Full Text] [Related]
18. HIV Nef expression favors the relative preservation of CD4+ T regulatory cells that retain some important suppressive functions. Chrobak P, Afkhami S, Priceputu E, Poudrier J, Meunier C, Hanna Z, Sparwasser T, Jolicoeur P. J Immunol; 2014 Feb 15; 192(4):1681-92. PubMed ID: 24465014 [Abstract] [Full Text] [Related]
19. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System. Shi J, Xiong R, Zhou T, Su P, Zhang X, Qiu X, Li H, Li S, Yu C, Wang B, Ding C, Smithgall TE, Zheng YH. J Virol; 2018 Jun 01; 92(11):. PubMed ID: 29514909 [Abstract] [Full Text] [Related]
20. CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates. Gray LR, Gabuzda D, Cowley D, Ellett A, Chiavaroli L, Wesselingh SL, Churchill MJ, Gorry PR. J Neurovirol; 2011 Feb 01; 17(1):82-91. PubMed ID: 21165790 [Abstract] [Full Text] [Related] Page: [Next] [New Search]