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Journal Abstract Search

139 related items for PubMed ID: 1944246

  • 1. Investigation of the mechanism of the interaction of tubulin with derivatives of 2-styrylquinazolin-4(3H)-one.
    Lin CM, Kang GJ, Roach MC, Jiang JB, Hesson DP, Luduena RF, Hamel E.
    Mol Pharmacol; 1991 Nov; 40(5):827-32. PubMed ID: 1944246
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of [3H]mebendazole binding to tubulin by structurally diverse microtubule inhibitors which interact at the colchicine binding site.
    Russell GJ, Lacey E.
    Biochem Mol Biol Int; 1995 May; 35(6):1153-9. PubMed ID: 7492951
    [Abstract] [Full Text] [Related]

  • 3. IKP104-induced decay of tubulin: role of the A-ring binding site of colchicine.
    Chaudhuri AR, Tomita I, Mizuhashi F, Murata K, Potenziano JL, Ludueña RF.
    Biochemistry; 1998 Dec 08; 37(49):17157-62. PubMed ID: 9860828
    [Abstract] [Full Text] [Related]

  • 4. Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues.
    Blokhin AV, Yoo HD, Geralds RS, Nagle DG, Gerwick WH, Hamel E.
    Mol Pharmacol; 1995 Sep 08; 48(3):523-31. PubMed ID: 7565634
    [Abstract] [Full Text] [Related]

  • 5. Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
    Batra JK, Jurd L, Hamel E.
    Mol Pharmacol; 1985 Jan 08; 27(1):94-102. PubMed ID: 3965931
    [Abstract] [Full Text] [Related]

  • 6. Kinetics of association and dissociation of two enantiomers, NSC 613863 (R)-(+) and NSC 613862 (S)-(-) (CI 980), to tubulin.
    Barbier P, Peyrot V, Dumortier C, D'Hoore A, Rener GA, Engelborghs Y.
    Biochemistry; 1996 Feb 13; 35(6):2008-15. PubMed ID: 8639685
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives.
    Goldbrunner M, Loidl G, Polossek T, Mannschreck A, von Angerer E.
    J Med Chem; 1997 Oct 24; 40(22):3524-33. PubMed ID: 9357519
    [Abstract] [Full Text] [Related]

  • 8. Derivatives of 5,6-diphenylpyridazin-3-one: synthetic antimitotic agents which interact with plant and mammalian tubulin at a new drug-binding site.
    Batra JK, Powers LJ, Hess FD, Hamel E.
    Cancer Res; 1986 Apr 24; 46(4 Pt 2):1889-93. PubMed ID: 3948171
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of bovine brain microtubule assembly in vitro by stypoldione.
    O'Brien ET, Jacobs RS, Wilson L.
    Mol Pharmacol; 1983 Nov 24; 24(3):493-9. PubMed ID: 6633509
    [Abstract] [Full Text] [Related]

  • 10. Stoichiometric and substoichiometric inhibition of tubulin self-assembly by colchicine analogues.
    Perez-Ramirez B, Andreu JM, Gorbunoff MJ, Timasheff SN.
    Biochemistry; 1996 Mar 12; 35(10):3277-85. PubMed ID: 8605164
    [Abstract] [Full Text] [Related]

  • 11. Comparative study of the colchicine binding site and the assembly of fish and mammalian microtubule proteins.
    de Pereda JM, Wallin M, Billger M, Andreu JM.
    Cell Motil Cytoskeleton; 1995 Mar 12; 30(2):153-63. PubMed ID: 7606808
    [Abstract] [Full Text] [Related]

  • 12. Alterations of rings B and C of colchicine are cumulative in overall binding to tubulin but modify each kinetic step.
    Dumortier C, Gorbunoff MJ, Andreu JM, Engelborghs Y.
    Biochemistry; 1996 Dec 10; 35(49):15900-6. PubMed ID: 8961956
    [Abstract] [Full Text] [Related]

  • 13. Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
    Gastpar R, Goldbrunner M, Marko D, von Angerer E.
    J Med Chem; 1998 Dec 03; 41(25):4965-72. PubMed ID: 9836614
    [Abstract] [Full Text] [Related]

  • 14. Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
    Lin CM, Ho HH, Pettit GR, Hamel E.
    Biochemistry; 1989 Aug 22; 28(17):6984-91. PubMed ID: 2819042
    [Abstract] [Full Text] [Related]

  • 15. The active GTP- and ground GDP-liganded states of tubulin are distinguished by the binding of chiral isomers of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate.
    Barbier P, Peyrot V, Leynadier D, Andreu JM.
    Biochemistry; 1998 Jan 13; 37(2):758-68. PubMed ID: 9425100
    [Abstract] [Full Text] [Related]

  • 16. Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin.
    Verdier-Pinard P, Sitachitta N, Rossi JV, Sackett DL, Gerwick WH, Hamel E.
    Arch Biochem Biophys; 1999 Oct 01; 370(1):51-8. PubMed ID: 10496976
    [Abstract] [Full Text] [Related]

  • 17. Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers.
    Hamel E, Lin CM, Flynn E, D'Amato RJ.
    Biochemistry; 1996 Jan 30; 35(4):1304-10. PubMed ID: 8573587
    [Abstract] [Full Text] [Related]

  • 18. Antitumor 2,3-dihydro-2-(aryl)-4(1H)-quinazolinone derivatives. Interactions with tubulin.
    Hamel E, Lin CM, Plowman J, Wang HK, Lee KH, Paull KD.
    Biochem Pharmacol; 1996 Jan 12; 51(1):53-9. PubMed ID: 8534268
    [Abstract] [Full Text] [Related]

  • 19. Interaction of estramustine with tubulin isotypes.
    Laing N, Dahllöf B, Hartley-Asp B, Ranganathan S, Tew KD.
    Biochemistry; 1997 Jan 28; 36(4):871-8. PubMed ID: 9020786
    [Abstract] [Full Text] [Related]

  • 20. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
    [Abstract] [Full Text] [Related]

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