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223 related items for PubMed ID: 19448108

  • 1. Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1.
    Wout PK, Sattlegger E, Sullivan SM, Maddock JR.
    Eukaryot Cell; 2009 Jul; 8(7):1061-71. PubMed ID: 19448108
    [Abstract] [Full Text] [Related]

  • 2. Evidence that Yih1 resides in a complex with ribosomes.
    Waller T, Lee SJ, Sattlegger E.
    FEBS J; 2012 May; 279(10):1761-76. PubMed ID: 22404850
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation.
    Visweswaraiah J, Lee SJ, Hinnebusch AG, Sattlegger E.
    J Biol Chem; 2012 Nov 02; 287(45):37757-68. PubMed ID: 22888004
    [Abstract] [Full Text] [Related]

  • 4. Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
    Pochopien AA, Beckert B, Kasvandik S, Berninghausen O, Beckmann R, Tenson T, Wilson DN.
    Proc Natl Acad Sci U S A; 2021 Apr 06; 118(14):. PubMed ID: 33790014
    [Abstract] [Full Text] [Related]

  • 5. Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.
    Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG.
    Mol Cell Biol; 1997 Aug 06; 17(8):4474-89. PubMed ID: 9234705
    [Abstract] [Full Text] [Related]

  • 6. Ribo-Seq and RNA-Seq of TMA46 ( DFRP1) and GIR2 ( DFRP2) knockout yeast strains.
    Egorov AA, Makeeva DS, Makarova NE, Bykov DA, Hrytseniuk YS, Mitkevich OV, Urakov VN, Alexandrov AI, Kulakovskiy IV, Dmitriev SE.
    F1000Res; 2021 Aug 06; 10():1162. PubMed ID: 34900236
    [Abstract] [Full Text] [Related]

  • 7. Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation.
    Sattlegger E, Hinnebusch AG.
    J Biol Chem; 2005 Apr 22; 280(16):16514-21. PubMed ID: 15722345
    [Abstract] [Full Text] [Related]

  • 8. Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.
    Sattlegger E, Barbosa JA, Moraes MC, Martins RM, Hinnebusch AG, Castilho BA.
    J Biol Chem; 2011 Mar 25; 286(12):10341-55. PubMed ID: 21239490
    [Abstract] [Full Text] [Related]

  • 9. Cell growth control by stable Rbg2/Gir2 complex formation under amino acid starvation.
    Ishikawa K, Ito K, Inoue J, Semba K.
    Genes Cells; 2013 Oct 25; 18(10):859-72. PubMed ID: 23899355
    [Abstract] [Full Text] [Related]

  • 10. GI domain-mediated association of the eukaryotic initiation factor 2alpha kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast.
    Kubota H, Sakaki Y, Ito T.
    J Biol Chem; 2000 Jul 07; 275(27):20243-6. PubMed ID: 10801780
    [Abstract] [Full Text] [Related]

  • 11. Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.
    Sattlegger E, Hinnebusch AG.
    EMBO J; 2000 Dec 01; 19(23):6622-33. PubMed ID: 11101534
    [Abstract] [Full Text] [Related]

  • 12. Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2.
    Lee SJ, Swanson MJ, Sattlegger E.
    Biochem J; 2015 Mar 15; 466(3):547-59. PubMed ID: 25437641
    [Abstract] [Full Text] [Related]

  • 13. Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
    Zeng F, Li X, Pires-Alves M, Chen X, Hawk CW, Jin H.
    Cell Rep; 2021 Oct 26; 37(4):109877. PubMed ID: 34706231
    [Abstract] [Full Text] [Related]

  • 14. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.
    Marton MJ, Crouch D, Hinnebusch AG.
    Mol Cell Biol; 1993 Jun 26; 13(6):3541-56. PubMed ID: 8497269
    [Abstract] [Full Text] [Related]

  • 15. Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2.
    Kubota H, Ota K, Sakaki Y, Ito T.
    J Biol Chem; 2001 May 18; 276(20):17591-6. PubMed ID: 11350982
    [Abstract] [Full Text] [Related]

  • 16. A genetic approach to identify amino acids in Gcn1 required for Gcn2 activation.
    Gottfried S, Koloamatangi SMBMJ, Daube C, Schiemann AH, Sattlegger E.
    PLoS One; 2022 May 18; 17(11):e0277648. PubMed ID: 36441697
    [Abstract] [Full Text] [Related]

  • 17. Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation.
    Garcia-Barrio M, Dong J, Ufano S, Hinnebusch AG.
    EMBO J; 2000 Apr 17; 19(8):1887-99. PubMed ID: 10775272
    [Abstract] [Full Text] [Related]

  • 18. Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress.
    Gupta R, Hinnebusch AG.
    Proc Natl Acad Sci U S A; 2023 Apr 18; 120(16):e2300521120. PubMed ID: 37043534
    [Abstract] [Full Text] [Related]

  • 19. Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity.
    Visweswaraiah J, Lageix S, Castilho BA, Izotova L, Kinzy TG, Hinnebusch AG, Sattlegger E.
    J Biol Chem; 2011 Oct 21; 286(42):36568-79. PubMed ID: 21849502
    [Abstract] [Full Text] [Related]

  • 20. Dom34-Hbs1 mediated dissociation of inactive 80S ribosomes promotes restart of translation after stress.
    van den Elzen AM, Schuller A, Green R, Séraphin B.
    EMBO J; 2014 Feb 03; 33(3):265-76. PubMed ID: 24424461
    [Abstract] [Full Text] [Related]

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