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Journal Abstract Search


704 related items for PubMed ID: 19454284

  • 1. Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator.
    Bijvelds MJ, Bot AG, Escher JC, De Jonge HR.
    Gastroenterology; 2009 Sep; 137(3):976-85. PubMed ID: 19454284
    [Abstract] [Full Text] [Related]

  • 2. Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR.
    MacVinish LJ, Cope G, Ropenga A, Cuthbert AW.
    Br J Pharmacol; 2007 Apr; 150(8):1055-65. PubMed ID: 17339840
    [Abstract] [Full Text] [Related]

  • 3. Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84.
    Ao M, Venkatasubramanian J, Boonkaewwan C, Ganesan N, Syed A, Benya RV, Rao MC.
    Dig Dis Sci; 2011 Feb; 56(2):339-51. PubMed ID: 21140215
    [Abstract] [Full Text] [Related]

  • 4. Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice.
    MacDonald KD, McKenzie KR, Henderson MJ, Hawkins CE, Vij N, Zeitlin PL.
    Am J Physiol Lung Cell Mol Physiol; 2008 Nov; 295(5):L933-40. PubMed ID: 18805957
    [Abstract] [Full Text] [Related]

  • 5. Traditional Chinese formula, lubricating gut pill, stimulates cAMP-dependent CI(−) secretion across rat distal colonic mucosa.
    Wu D, Zhou J, Wang X, Cui B, An R, Shi H, Yuan J, Hu Z.
    J Ethnopharmacol; 2011 Mar 24; 134(2):406-13. PubMed ID: 21195154
    [Abstract] [Full Text] [Related]

  • 6. Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone.
    Moeser AJ, Nighot PK, Engelke KJ, Ueno R, Blikslager AT.
    Am J Physiol Gastrointest Liver Physiol; 2007 Feb 24; 292(2):G647-56. PubMed ID: 17053162
    [Abstract] [Full Text] [Related]

  • 7. Identification of the fatty acid activation site on human ClC-2.
    Cuppoletti J, Tewari KP, Chakrabarti J, Malinowska DH.
    Am J Physiol Cell Physiol; 2017 Jun 01; 312(6):C707-C723. PubMed ID: 28424169
    [Abstract] [Full Text] [Related]

  • 8. Lubiprostone targets prostanoid EP₄ receptors in ovine airways.
    Cuthbert AW.
    Br J Pharmacol; 2011 Jan 01; 162(2):508-20. PubMed ID: 20883477
    [Abstract] [Full Text] [Related]

  • 9. Activation of CFTR by ASBT-mediated bile salt absorption.
    Bijvelds MJ, Jorna H, Verkade HJ, Bot AG, Hofmann F, Agellon LB, Sinaasappel M, de Jonge HR.
    Am J Physiol Gastrointest Liver Physiol; 2005 Nov 01; 289(5):G870-9. PubMed ID: 16037545
    [Abstract] [Full Text] [Related]

  • 10. Use of the chloride channel activator lubiprostone for constipation in adults with cystic fibrosis: a case series.
    O'Brien CE, Anderson PJ, Stowe CD.
    Ann Pharmacother; 2010 Mar 01; 44(3):577-81. PubMed ID: 20179256
    [Abstract] [Full Text] [Related]

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  • 12. Activation of PPARgamma by rosiglitazone attenuates intestinal Cl- secretion.
    Bajwa PJ, Lee JW, Straus DS, Lytle C.
    Am J Physiol Gastrointest Liver Physiol; 2009 Jul 01; 297(1):G82-9. PubMed ID: 19443733
    [Abstract] [Full Text] [Related]

  • 13. Role of K(V)LQT1 in cyclic adenosine monophosphate-mediated Cl(-) secretion in human airway epithelia.
    Mall M, Wissner A, Schreiber R, Kuehr J, Seydewitz HH, Brandis M, Greger R, Kunzelmann K.
    Am J Respir Cell Mol Biol; 2000 Sep 01; 23(3):283-9. PubMed ID: 10970817
    [Abstract] [Full Text] [Related]

  • 14. Lubiprostone prevents nonsteroidal anti-inflammatory drug-induced small intestinal damage by suppressing the expression of inflammatory mediators via EP4 receptors.
    Hayashi S, Kurata N, Yamaguchi A, Amagase K, Takeuchi K.
    J Pharmacol Exp Ther; 2014 Jun 01; 349(3):470-9. PubMed ID: 24713141
    [Abstract] [Full Text] [Related]

  • 15. Activation of AMP-activated protein kinase reduces cAMP-mediated epithelial chloride secretion.
    Walker J, Jijon HB, Churchill T, Kulka M, Madsen KL.
    Am J Physiol Gastrointest Liver Physiol; 2003 Nov 01; 285(5):G850-60. PubMed ID: 12869384
    [Abstract] [Full Text] [Related]

  • 16. Lubiprostone is non-selective activator of cAMP-gated ion channels and Clc-2 has a minor role in its prosecretory effect in intestinal epithelial cells.
    Oak AA, Chu T, Yottasan P, Chhetri PD, Zhu J, Du Bois J, Cil O.
    Mol Pharmacol; 2022 Jun 09; 102(2):106-15. PubMed ID: 35680165
    [Abstract] [Full Text] [Related]

  • 17. Cellular differentiation is required for cAMP but not Ca(2+)-dependent Cl- secretion in colonic epithelial cells expressing high levels of cystic fibrosis transmembrane conductance regulator.
    Morris AP, Cunningham SA, Benos DJ, Frizzell RA.
    J Biol Chem; 1992 Mar 15; 267(8):5575-83. PubMed ID: 1372005
    [Abstract] [Full Text] [Related]

  • 18. Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents.
    Cuppoletti J, Chakrabarti J, Tewari K, Malinowska DH.
    Cell Biochem Biophys; 2013 May 15; 66(1):53-63. PubMed ID: 22918821
    [Abstract] [Full Text] [Related]

  • 19. Abolition of Ca2+-mediated intestinal anion secretion and increased stool dehydration in mice lacking the intermediate conductance Ca2+-dependent K+ channel Kcnn4.
    Flores CA, Melvin JE, Figueroa CD, Sepúlveda FV.
    J Physiol; 2007 Sep 01; 583(Pt 2):705-17. PubMed ID: 17584847
    [Abstract] [Full Text] [Related]

  • 20. Differentiation between human ClC-2 and CFTR Cl- channels with pharmacological agents.
    Cuppoletti J, Chakrabarti J, Tewari KP, Malinowska DH.
    Am J Physiol Cell Physiol; 2014 Sep 01; 307(5):C479-92. PubMed ID: 25009109
    [Abstract] [Full Text] [Related]


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