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1212 related items for PubMed ID: 19474002

  • 1. Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.
    Seth R, Crook S, Ibrahem S, Fadhil W, Jackson D, Ilyas M.
    Gut; 2009 Sep; 58(9):1234-41. PubMed ID: 19474002
    [Abstract] [Full Text] [Related]

  • 2. Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
    Dawson H, Galván JA, Helbling M, Muller DE, Karamitopoulou E, Koelzer VH, Economou M, Hammer C, Lugli A, Zlobec I.
    Int J Cancer; 2014 May 15; 134(10):2342-51. PubMed ID: 24166180
    [Abstract] [Full Text] [Related]

  • 3. Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation.
    Lee S, Cho NY, Choi M, Yoo EJ, Kim JH, Kang GH.
    Pathol Int; 2008 Feb 15; 58(2):104-13. PubMed ID: 18199160
    [Abstract] [Full Text] [Related]

  • 4. Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer.
    Nagasaka T, Koi M, Kloor M, Gebert J, Vilkin A, Nishida N, Shin SK, Sasamoto H, Tanaka N, Matsubara N, Boland CR, Goel A.
    Gastroenterology; 2008 Jun 15; 134(7):1950-60, 1960.e1. PubMed ID: 18435933
    [Abstract] [Full Text] [Related]

  • 5. KRAS, BRAF and PIK3CA mutations in human colorectal cancer: relationship with metastatic colorectal cancer.
    Li HT, Lu YY, An YX, Wang X, Zhao QC.
    Oncol Rep; 2011 Jun 15; 25(6):1691-7. PubMed ID: 21424126
    [Abstract] [Full Text] [Related]

  • 6. Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
    Ogino S, Kawasaki T, Kirkner GJ, Ogawa A, Dorfman I, Loda M, Fuchs CS.
    J Pathol; 2006 Oct 15; 210(2):147-54. PubMed ID: 16850502
    [Abstract] [Full Text] [Related]

  • 7. BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
    Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R.
    BMC Cancer; 2008 Sep 09; 8():255. PubMed ID: 18782444
    [Abstract] [Full Text] [Related]

  • 8. Mutation analysis of BRAF exon 15 and KRAS codons 12 and 13 in Moroccan patients with colorectal cancer.
    Bennani B, Gilles S, Fina F, Nanni I, Ibrahimi SA, Riffi AA, Nejjari C, Benajeh DA, El Abkari M, Martin PM, Ouafik L.
    Int J Biol Markers; 2010 Sep 09; 25(4):179-84. PubMed ID: 21161938
    [Abstract] [Full Text] [Related]

  • 9. [Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].
    Gao J, Sun ZW, Li YY, Shen L.
    Zhonghua Bing Li Xue Za Zhi; 2012 Sep 09; 41(9):579-83. PubMed ID: 23157823
    [Abstract] [Full Text] [Related]

  • 10. BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status.
    Yang S, Farraye FA, Mack C, Posnik O, O'Brien MJ.
    Am J Surg Pathol; 2004 Nov 09; 28(11):1452-9. PubMed ID: 15489648
    [Abstract] [Full Text] [Related]

  • 11. [Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].
    Ling Y, Ying JM, Qiu T, Shan L, Guo L, Lü N.
    Zhonghua Bing Li Xue Za Zhi; 2012 Sep 09; 41(9):590-4. PubMed ID: 23157825
    [Abstract] [Full Text] [Related]

  • 12. High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
    Guedes JG, Veiga I, Rocha P, Pinto P, Pinto C, Pinheiro M, Peixoto A, Fragoso M, Raimundo A, Ferreira P, Machado M, Sousa N, Lopes P, Araújo A, Macedo J, Alves F, Coutinho C, Henrique R, Santos LL, Teixeira MR.
    BMC Cancer; 2013 Apr 01; 13():169. PubMed ID: 23548132
    [Abstract] [Full Text] [Related]

  • 13. Cycleave polymerase chain reaction method is practically applicable for V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS)/V-raf murine sarcoma viral oncogene homolog B1 (BRAF) genotyping in colorectal cancer.
    Yokota T, Shibata N, Ura T, Takahari D, Shitara K, Muro K, Yatabe Y.
    Transl Res; 2010 Aug 01; 156(2):98-105. PubMed ID: 20627194
    [Abstract] [Full Text] [Related]

  • 14. Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia.
    Yip WK, Choo CW, Leong VC, Leong PP, Jabar MF, Seow HF.
    APMIS; 2013 Oct 01; 121(10):954-66. PubMed ID: 23992303
    [Abstract] [Full Text] [Related]

  • 15. High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer.
    Simi L, Pratesi N, Vignoli M, Sestini R, Cianchi F, Valanzano R, Nobili S, Mini E, Pazzagli M, Orlando C.
    Am J Clin Pathol; 2008 Aug 01; 130(2):247-53. PubMed ID: 18628094
    [Abstract] [Full Text] [Related]

  • 16. [Comparative analysis of real-time quantitative PCR-Sanger sequencing method and TaqMan probe method for detection of KRAS/BRAF mutation in colorectal carcinomas].
    Zhang X, Wang Y, Gao N, Wang J.
    Zhonghua Bing Li Xue Za Zhi; 2014 Feb 01; 43(2):77-82. PubMed ID: 24742565
    [Abstract] [Full Text] [Related]

  • 17. Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.
    Lee J, Lee I, Han B, Park JO, Jang J, Park C, Kang WK.
    J Natl Cancer Inst; 2011 Apr 20; 103(8):674-88. PubMed ID: 21398618
    [Abstract] [Full Text] [Related]

  • 18. Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
    Vaughn CP, Zobell SD, Furtado LV, Baker CL, Samowitz WS.
    Genes Chromosomes Cancer; 2011 May 20; 50(5):307-12. PubMed ID: 21305640
    [Abstract] [Full Text] [Related]

  • 19. Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.
    Packham D, Ward RL, Ap Lin V, Hawkins NJ, Hitchins MP.
    Diagn Mol Pathol; 2009 Jun 20; 18(2):62-71. PubMed ID: 19430299
    [Abstract] [Full Text] [Related]

  • 20. High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
    Naghibalhossaini F, Hosseini HM, Mokarram P, Zamani M.
    Pathol Oncol Res; 2011 Dec 20; 17(4):819-25. PubMed ID: 21455633
    [Abstract] [Full Text] [Related]

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