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Journal Abstract Search

95 related items for PubMed ID: 19475539

  • 1. Pharmacokinetics of sertindole and its metabolite dehydrosertindole in rats and characterization of their comparative pharmacodynamics based on in vivo D2 receptor occupancy and behavioural conditioned avoidance response.
    Bundgaard C, Larsen F, Kreilgaard M, Brennum LT, Olsen CK.
    Biopharm Drug Dispos; 2009 May; 30(4):209-20. PubMed ID: 19475539
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  • 2. Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics.
    Olsen CK, Brennum LT, Kreilgaard M.
    Eur J Pharmacol; 2008 Apr 28; 584(2-3):318-27. PubMed ID: 18325493
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  • 5. In vivo occupation of dopamine D1, D2 and serotonin (5-HT)2A receptors by sertindole in the rat brain.
    Takahashi Y, Kusumi I, Ishikane T, Matsubara S, Koyama T.
    J Psychiatry Neurosci; 1998 May 28; 23(3):157-62. PubMed ID: 9595889
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  • 11. Sertindole, in contrast to clozapine and olanzapine, does not disrupt water maze performance after acute or chronic treatment.
    Didriksen M, Kreilgaard M, Arnt J.
    Eur J Pharmacol; 2006 Aug 07; 542(1-3):108-15. PubMed ID: 16806167
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  • 12. Predicting the dopamine D2 receptor occupancy of ropinirole in rats using positron emission tomography and pharmacokinetic-pharmacodynamic modeling.
    Huang C, Wang Z, Liu L, Liu X, Dong J, Xu Q, Zhang B, Miao L.
    Xenobiotica; 2019 Feb 07; 49(2):143-151. PubMed ID: 29334326
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  • 14. The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat.
    Natesan S, Svensson KA, Reckless GE, Nobrega JN, Barlow KB, Johansson AM, Kapur S.
    J Pharmacol Exp Ther; 2006 Aug 07; 318(2):810-8. PubMed ID: 16648369
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  • 16. Pharmacokinetic-pharmacodynamic modeling of the hydroxy lerisetron metabolite L6-OH in rats: an integrated parent-metabolite model.
    Ortega F, Quintana A, Suárez E, Lukas JC, Jauregizar N, de la Fuente L, Lucero ML, Gonzalo A, Orjales A, Calvo R.
    Pharm Res; 2005 Nov 07; 22(11):1769-82. PubMed ID: 16158214
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  • 19. Dissociation between in vivo occupancy and functional antagonism of dopamine D2 receptors: comparing aripiprazole to other antipsychotics in animal models.
    Natesan S, Reckless GE, Nobrega JN, Fletcher PJ, Kapur S.
    Neuropsychopharmacology; 2006 Sep 07; 31(9):1854-63. PubMed ID: 16319908
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