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Journal Abstract Search

908 related items for PubMed ID: 19477685

  • 1. Recent progress in fragment-based lead discovery.
    Schulz MN, Hubbard RE.
    Curr Opin Pharmacol; 2009 Oct; 9(5):615-21. PubMed ID: 19477685
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  • 2. From purified GPCRs to drug discovery: the promise of protein-based methodologies.
    Alkhalfioui F, Magnin T, Wagner R.
    Curr Opin Pharmacol; 2009 Oct; 9(5):629-35. PubMed ID: 19443270
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  • 7. Hit finding: towards 'smarter' approaches.
    Langer T, Hoffmann R, Bryant S, Lesur B.
    Curr Opin Pharmacol; 2009 Oct; 9(5):589-93. PubMed ID: 19576852
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  • 9. Small-world phenomena in chemical library networks: application to fragment-based drug discovery.
    Tanaka N, Ohno K, Niimi T, Moritomo A, Mori K, Orita M.
    J Chem Inf Model; 2009 Dec; 49(12):2677-86. PubMed ID: 19961207
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  • 10. Enhancements of screening collections to address areas of unmet medical need: an industry perspective.
    Drewry DH, Macarron R.
    Curr Opin Chem Biol; 2010 Jun; 14(3):289-98. PubMed ID: 20413343
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  • 11. Ligand specificity, privileged substructures and protein druggability from fragment-based screening.
    Barelier S, Krimm I.
    Curr Opin Chem Biol; 2011 Aug; 15(4):469-74. PubMed ID: 21411360
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  • 12. Making drugs on proteins: site-directed ligand discovery for fragment-based lead assembly.
    Erlanson DA, Hansen SK.
    Curr Opin Chem Biol; 2004 Aug; 8(4):399-406. PubMed ID: 15288250
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  • 15. High-throughput X-ray crystallography for drug discovery.
    Blundell TL, Patel S.
    Curr Opin Pharmacol; 2004 Oct; 4(5):490-6. PubMed ID: 15351354
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  • 20. Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.
    Kobayashi M, Retra K, Figaroa F, Hollander JG, Ab E, Heetebrij RJ, Irth H, Siegal G.
    J Biomol Screen; 2010 Sep; 15(8):978-89. PubMed ID: 20817886
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