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183 related items for PubMed ID: 19486266

  • 1. Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity.
    Cummings DF, Ericksen SS, Schetz JA.
    J Neurochem; 2009 Jul; 110(1):45-57. PubMed ID: 19486266
    [Abstract] [Full Text] [Related]

  • 2. Nonconserved residues in the second transmembrane-spanning domain of the D(4) dopamine receptor are molecular determinants of D(4)-selective pharmacology.
    Schetz JA, Benjamin PS, Sibley DR.
    Mol Pharmacol; 2000 Jan; 57(1):144-52. PubMed ID: 10617689
    [Abstract] [Full Text] [Related]

  • 3. Chimeric D1/D2 dopamine receptors. Distinct determinants of selective efficacy, potency, and signal transduction.
    Kozell LB, Machida CA, Neve RL, Neve KA.
    J Biol Chem; 1994 Dec 02; 269(48):30299-306. PubMed ID: 7982941
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands.
    Li A, Mishra Y, Malik M, Wang Q, Li S, Taylor M, Reichert DE, Luedtke RR, Mach RH.
    Bioorg Med Chem; 2013 Jun 01; 21(11):2988-98. PubMed ID: 23618707
    [Abstract] [Full Text] [Related]

  • 5. Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain.
    Kortagere S, Gmeiner P, Weinstein H, Schetz JA.
    Mol Pharmacol; 2004 Dec 01; 66(6):1491-9. PubMed ID: 15448188
    [Abstract] [Full Text] [Related]

  • 6. Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice.
    Collins GT, Truccone A, Haji-Abdi F, Newman AH, Grundt P, Rice KC, Husbands SM, Greedy BM, Enguehard-Gueiffier C, Gueiffier A, Chen J, Wang S, Katz JL, Grandy DK, Sunahara RK, Woods JH.
    J Pharmacol Exp Ther; 2009 Apr 01; 329(1):210-7. PubMed ID: 19136638
    [Abstract] [Full Text] [Related]

  • 7. Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D2 and D3 Receptors.
    Newton CL, Wood MD, Strange PG.
    PLoS One; 2016 Apr 01; 11(7):e0158808. PubMed ID: 27379794
    [Abstract] [Full Text] [Related]

  • 8. Neuropharmacological assessment of potential dopamine D4 receptor-selective radioligands.
    Kula NS, Tarazi FI, Baldessarini RJ, Xu L, Bakthavachalam V, Pounds S, True CD.
    Eur J Pharmacol; 1999 Feb 12; 367(1):139-42. PubMed ID: 10082277
    [Abstract] [Full Text] [Related]

  • 9. Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor.
    Ericksen SS, Cummings DF, Teer ME, Amdani S, Schetz JA.
    J Pharmacol Exp Ther; 2012 Aug 12; 342(2):472-85. PubMed ID: 22588261
    [Abstract] [Full Text] [Related]

  • 10. Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548.
    Cummings DF, Ericksen SS, Goetz A, Schetz JA.
    J Pharmacol Exp Ther; 2010 Jun 12; 333(3):682-95. PubMed ID: 20215412
    [Abstract] [Full Text] [Related]

  • 11. Dopamine D5 receptor agonist high affinity and constitutive activity profile conferred by carboxyl-terminal tail sequence.
    Demchyshyn LL, McConkey F, Niznik HB.
    J Biol Chem; 2000 Aug 04; 275(31):23446-55. PubMed ID: 10807903
    [Abstract] [Full Text] [Related]

  • 12. Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy-2,3, 12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands.
    Claudi F, Di Stefano A, Napolitani F, Cingolani GM, Giorgioni G, Fontenla JA, Montenegro GY, Rivas ME, Rosa E, Michelotto B, Orlando G, Brunetti L.
    J Med Chem; 2000 Feb 24; 43(4):599-608. PubMed ID: 10691686
    [Abstract] [Full Text] [Related]

  • 13. [3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor.
    Moreland RB, Terranova MA, Chang R, Uchic ME, Matulenko MA, Surber BW, Stewart AO, Brioni JD.
    Eur J Pharmacol; 2004 Aug 23; 497(2):147-54. PubMed ID: 15306199
    [Abstract] [Full Text] [Related]

  • 14. Identification of amino acid determinants of dopamine 2 receptor synthetic agonist function.
    Al-Fulaij MA, Ren Y, Beinborn M, Kopin AS.
    J Pharmacol Exp Ther; 2007 Apr 23; 321(1):298-307. PubMed ID: 17204745
    [Abstract] [Full Text] [Related]

  • 15. Role of conserved serine residues in the interaction of agonists with D3 dopamine receptors.
    Sartania N, Strange PG.
    J Neurochem; 1999 Jun 23; 72(6):2621-4. PubMed ID: 10349875
    [Abstract] [Full Text] [Related]

  • 16. 6-(4-Benzylpiperazin-1-yl)benzodioxanes as selective ligands at cloned primate dopamine D(4) receptors.
    Hodgetts KJ, Kieltyka A, Brodbeck R, Tran JN, Wasley JW, Thurkauf A.
    Bioorg Med Chem; 2001 Dec 23; 9(12):3207-13. PubMed ID: 11711296
    [Abstract] [Full Text] [Related]

  • 17. Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments.
    Simpson MM, Ballesteros JA, Chiappa V, Chen J, Suehiro M, Hartman DS, Godel T, Snyder LA, Sakmar TP, Javitch JA.
    Mol Pharmacol; 1999 Dec 23; 56(6):1116-26. PubMed ID: 10570038
    [Abstract] [Full Text] [Related]

  • 18. Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626.
    Bowery BJ, Razzaque Z, Emms F, Patel S, Freedman S, Bristow L, Kulagowski J, Seabrook GR.
    Br J Pharmacol; 1996 Dec 23; 119(7):1491-7. PubMed ID: 8968560
    [Abstract] [Full Text] [Related]

  • 19. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.
    Heinrich JN, Brennan J, Lai MH, Sullivan K, Hornby G, Popiolek M, Jiang LX, Pausch MH, Stack G, Marquis KL, Andree TH.
    Eur J Pharmacol; 2006 Dec 15; 552(1-3):36-45. PubMed ID: 17056032
    [Abstract] [Full Text] [Related]

  • 20. Characterization of a novel iodinated ligand, IPMPP, for human dopamine D4 receptors expressed in CHO cells.
    Kung MP, Stevenson DA, Zhuang ZP, Vessotskie JM, Chumpradit S, Sun XM, Kung HF.
    Life Sci; 1997 Dec 15; 60(2):91-100. PubMed ID: 9000114
    [Abstract] [Full Text] [Related]

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