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Journal Abstract Search

328 related items for PubMed ID: 19487308

  • 1. Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.
    Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning JC, Schubert M.
    FASEB J; 2009 Oct; 23(10):3315-24. PubMed ID: 19487308
    [Abstract] [Full Text] [Related]

  • 2. Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease.
    Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M.
    Age (Dordr); 2013 Feb; 35(1):83-101. PubMed ID: 22057897
    [Abstract] [Full Text] [Related]

  • 3. Neuron-specific deletion of a single copy of the insulin-like growth factor-1 receptor gene reduces fat accumulation during aging.
    Freude S, Schilbach K, Hettich MM, Brönneke HS, Zemva J, Krone W, Schubert M.
    Horm Metab Res; 2012 Feb; 44(2):99-104. PubMed ID: 22198814
    [Abstract] [Full Text] [Related]

  • 4. The role of neuronal insulin/insulin-like growth factor-1 signaling for the pathogenesis of Alzheimer's disease: possible therapeutic implications.
    Zemva J, Schubert M.
    CNS Neurol Disord Drug Targets; 2014 Mar; 13(2):322-37. PubMed ID: 24059318
    [Abstract] [Full Text] [Related]

  • 5. IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.
    Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M.
    J Neurochem; 2008 Nov; 107(4):907-17. PubMed ID: 18717815
    [Abstract] [Full Text] [Related]

  • 6. Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance.
    Gontier G, George C, Chaker Z, Holzenberger M, Aïd S.
    J Neurosci; 2015 Aug 19; 35(33):11500-13. PubMed ID: 26290229
    [Abstract] [Full Text] [Related]

  • 7. The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease.
    Freude S, Schilbach K, Schubert M.
    Curr Alzheimer Res; 2009 Jun 19; 6(3):213-23. PubMed ID: 19519303
    [Abstract] [Full Text] [Related]

  • 8. Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling.
    Moloney AM, Griffin RJ, Timmons S, O'Connor R, Ravid R, O'Neill C.
    Neurobiol Aging; 2010 Feb 19; 31(2):224-43. PubMed ID: 18479783
    [Abstract] [Full Text] [Related]

  • 9. Impaired neuronal insulin signaling precedes Aβ42 accumulation in female AβPPsw/PS1ΔE9 mice.
    Chua LM, Lim ML, Chong PR, Hu ZP, Cheung NS, Wong BS.
    J Alzheimers Dis; 2012 Feb 19; 29(4):783-91. PubMed ID: 22337827
    [Abstract] [Full Text] [Related]

  • 10. Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease.
    Wu ZL, Ciallella JR, Flood DG, O'Kane TM, Bozyczko-Coyne D, Savage MJ.
    Neurobiol Aging; 2006 Mar 19; 27(3):377-86. PubMed ID: 15927307
    [Abstract] [Full Text] [Related]

  • 11. Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models.
    Zhang B, Tang XC, Zhang HY.
    J Neurosci Res; 2013 May 19; 91(5):717-25. PubMed ID: 23401344
    [Abstract] [Full Text] [Related]

  • 12. Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-β peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus.
    Ito S, Ménard M, Atkinson T, Gaudet C, Brown L, Whitfield J, Chakravarthy B.
    J Alzheimers Dis; 2012 May 19; 31(3):493-506. PubMed ID: 22635104
    [Abstract] [Full Text] [Related]

  • 13. Divalent metal transporter 1 is involved in amyloid precursor protein processing and Abeta generation.
    Zheng W, Xin N, Chi ZH, Zhao BL, Zhang J, Li JY, Wang ZY.
    FASEB J; 2009 Dec 19; 23(12):4207-17. PubMed ID: 19679638
    [Abstract] [Full Text] [Related]

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  • 15. Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling.
    Sun H, Tu X, Liu M, Baserga R.
    J Cell Physiol; 2007 Sep 19; 212(3):780-6. PubMed ID: 17443674
    [Abstract] [Full Text] [Related]

  • 16. Genetic Reduction of Insulin Signaling Mitigates Amyloid-β Deposition by Promoting Expression of Extracellular Matrix Proteins in the Brain.
    Sano T, Ochiai T, Nagayama T, Nakamura A, Kubota N, Kadowaki T, Wakabayashi T, Iwatsubo T.
    J Neurosci; 2023 Oct 25; 43(43):7226-7241. PubMed ID: 37699718
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  • 19. Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells.
    Tsukamoto E, Hashimoto Y, Kanekura K, Niikura T, Aiso S, Nishimoto I.
    J Neurosci Res; 2003 Sep 01; 73(5):627-36. PubMed ID: 12929130
    [Abstract] [Full Text] [Related]

  • 20. Intracellular Aß triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease.
    Christensen DZ, Bayer TA, Wirths O.
    Neurobiol Aging; 2010 Jul 01; 31(7):1153-63. PubMed ID: 18771817
    [Abstract] [Full Text] [Related]

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