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Journal Abstract Search

379 related items for PubMed ID: 19487463

  • 1. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
    Acosta-Jaquez HA, Keller JA, Foster KG, Ekim B, Soliman GA, Feener EP, Ballif BA, Fingar DC.
    Mol Cell Biol; 2009 Aug; 29(15):4308-24. PubMed ID: 19487463
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  • 2. mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action.
    Soliman GA, Acosta-Jaquez HA, Dunlop EA, Ekim B, Maj NE, Tee AR, Fingar DC.
    J Biol Chem; 2010 Mar 12; 285(11):7866-79. PubMed ID: 20022946
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  • 3. mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression.
    Ekim B, Magnuson B, Acosta-Jaquez HA, Keller JA, Feener EP, Fingar DC.
    Mol Cell Biol; 2011 Jul 12; 31(14):2787-801. PubMed ID: 21576368
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  • 11. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
    Wang L, Harris TE, Roth RA, Lawrence JC.
    J Biol Chem; 2007 Jul 06; 282(27):20036-44. PubMed ID: 17510057
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  • 13. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
    Wu D, Chapman JR, Wang L, Harris TE, Shabanowitz J, Hunt DF, Fu Z.
    J Biol Chem; 2012 Apr 06; 287(15):12510-9. PubMed ID: 22356909
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  • 17. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
    Breuleux M, Klopfenstein M, Stephan C, Doughty CA, Barys L, Maira SM, Kwiatkowski D, Lane HA.
    Mol Cancer Ther; 2009 Apr 06; 8(4):742-53. PubMed ID: 19372546
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  • 19. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex.
    Fonseca BD, Smith EM, Lee VH, MacKintosh C, Proud CG.
    J Biol Chem; 2007 Aug 24; 282(34):24514-24. PubMed ID: 17604271
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