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Journal Abstract Search

221 related items for PubMed ID: 1949909

  • 1. Studies of paracetamol/phenacetin toxicity: isolation and characterization of p-aminophenol-glutathione conjugate.
    Eyanagi R, Hisanari Y, Shigematsu H.
    Xenobiotica; 1991 Jun; 21(6):793-803. PubMed ID: 1949909
    [Abstract] [Full Text] [Related]

  • 2. Reaction of mutagenic phenacetin metabolites with glutathione and DNA. Possible implications for toxicity.
    Mulder GJ, Kadlubar FF, Mays JB, Hinson JA.
    Mol Pharmacol; 1984 Sep; 26(2):342-7. PubMed ID: 6482879
    [Abstract] [Full Text] [Related]

  • 3. A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues.
    Soglia JR, Contillo LG, Kalgutkar AS, Zhao S, Hop CE, Boyd JG, Cole MJ.
    Chem Res Toxicol; 2006 Mar; 19(3):480-90. PubMed ID: 16544956
    [Abstract] [Full Text] [Related]

  • 4. Horseradish peroxidase-catalyzed oxidation of acetaminophen to intermediates that form polymers or conjugate with glutathione.
    Potter DW, Miller DW, Hinson JA.
    Mol Pharmacol; 1986 Feb; 29(2):155-62. PubMed ID: 3951429
    [Abstract] [Full Text] [Related]

  • 5. In vitro metabolic activation of thiabendazole via 5-hydroxythiabendazole: identification of a glutathione conjugate of 5-hydroxythiabendazole.
    Dalvie D, Smith E, Deese A, Bowlin S.
    Drug Metab Dispos; 2006 Apr; 34(4):709-17. PubMed ID: 16434547
    [Abstract] [Full Text] [Related]

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  • 8. Structure determination of a diuretic-glutathione conjugate by mass and n.m.r. spectrometry.
    Higaki J, Kikuchi J, Ikenishi Y, Hirata M.
    Xenobiotica; 1991 Jan; 21(1):47-51. PubMed ID: 2003366
    [Abstract] [Full Text] [Related]

  • 9. Activity of phenacetin O-deethylase in rat liver: effect of inducers and inhibitors in vivo.
    Starek A.
    Pol J Occup Med Environ Health; 1991 Jan; 4(1):67-75. PubMed ID: 1818647
    [Abstract] [Full Text] [Related]

  • 10. Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney.
    Koob M, Dekant W.
    Drug Metab Dispos; 1990 Jan; 18(6):911-6. PubMed ID: 1981536
    [Abstract] [Full Text] [Related]

  • 11. Covalent binding of catechol estrogens to glutathione catalyzed by horseradish peroxidase, lactoperoxidase, or rat liver microsomes.
    Cao K, Devanesan PD, Ramanathan R, Gross ML, Rogan EG, Cavalieri EL.
    Chem Res Toxicol; 1998 Aug; 11(8):917-24. PubMed ID: 9705754
    [Abstract] [Full Text] [Related]

  • 12. Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
    Hu JJ, Lee MJ, Vapiwala M, Reuhl K, Thomas PE, Yang CS.
    Toxicol Appl Pharmacol; 1993 Sep; 122(1):16-26. PubMed ID: 8378930
    [Abstract] [Full Text] [Related]

  • 13. Metabolic activation of phenacetin and phenetidine by several forms of cytochrome P-450 purified from liver microsomes of rats and hamsters.
    Nohmi T, Mizokami K, Kawano S, Fukuhara M, Ishidate M.
    Jpn J Cancer Res; 1987 Feb; 78(2):153-61. PubMed ID: 3104258
    [Abstract] [Full Text] [Related]

  • 14. Enzymatic conjugation of hexachloro-1,3-butadiene with glutathione. Formation of 1-(glutathion-S-yl)-1,2,3,4,4-pentachlorobuta-1,3-diene and 1,4-bis(glutathion-S-yl)-1,2,3,4-tetrachlorobuta-1,3-diene.
    Dekant W, Vamvakas S, Henschler D, Anders MW.
    Drug Metab Dispos; 1988 Feb; 16(5):701-6. PubMed ID: 2906593
    [Abstract] [Full Text] [Related]

  • 15. Characterization and mechanism of formation of reactive products formed during peroxidase-catalyzed oxidation of p-phenetidine. Trapping of reactive species by reduced glutathione and butylated hydroxyanisole.
    Ross D, Larsson R, Norbeck K, Ryhage R, Moldéus P.
    Mol Pharmacol; 1985 Feb; 27(2):277-86. PubMed ID: 3969071
    [Abstract] [Full Text] [Related]

  • 16. Nephrotoxicity of 4-aminophenol glutathione conjugate.
    Fowler LM, Moore RB, Foster JR, Lock EA.
    Hum Exp Toxicol; 1991 Nov; 10(6):451-9. PubMed ID: 1687859
    [Abstract] [Full Text] [Related]

  • 17. Prediction of in vivo potential for metabolic activation of drugs into chemically reactive intermediate: correlation of in vitro and in vivo generation of reactive intermediates and in vitro glutathione conjugate formation in rats and humans.
    Masubuchi N, Makino C, Murayama N.
    Chem Res Toxicol; 2007 Mar; 20(3):455-64. PubMed ID: 17309281
    [Abstract] [Full Text] [Related]

  • 18. Mechanism of increased hepatotoxicity of acetaminophen by the simultaneous administration of caffeine in the rat.
    Sato C, Izumi N.
    J Pharmacol Exp Ther; 1989 Mar; 248(3):1243-7. PubMed ID: 2703973
    [Abstract] [Full Text] [Related]

  • 19. Renal PGE2 production in the human and rat following phenacetin, acetaminophen and p-aminophenol.
    Goodin MG, Walker RJ, Rosengren RJ.
    Res Commun Mol Pathol Pharmacol; 2002 Mar; 111(1-4):153-66. PubMed ID: 14632321
    [Abstract] [Full Text] [Related]

  • 20. The oxidative metabolism of hydralazine by rat liver microsomes.
    LaCagnin LB, Colby HD, O'Donnell JP.
    Drug Metab Dispos; 1986 Mar; 14(5):549-54. PubMed ID: 2876860
    [Abstract] [Full Text] [Related]

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