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Journal Abstract Search

129 related items for PubMed ID: 19503925

  • 1. Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides.
    Berry NG, Iddon L, Iqbal M, Meng X, Jayapal P, Johnson CH, Nicholson JK, Lindon JC, Harding JR, Wilson ID, Stachulski AV.
    Org Biomol Chem; 2009 Jun 21; 7(12):2525-33. PubMed ID: 19503925
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  • 2. Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides.
    Iddon L, Richards SE, Johnson CH, Harding JR, Wilson ID, Nicholson JK, Lindon JC, Stachulski AV.
    Org Biomol Chem; 2011 Feb 07; 9(3):926-34. PubMed ID: 21152488
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  • 3. Transacylation and hydrolysis of the acyl glucuronides of ibuprofen and its α-methyl-substituted analogues investigated by 1H NMR spectroscopy and computational chemistry: Implications for drug design.
    Richards SE, Bradshaw PR, Johnson CH, Stachulski AV, Athersuch TJ, Nicholson JK, Lindon JC, Wilson ID.
    J Pharm Biomed Anal; 2024 Aug 15; 246():116238. PubMed ID: 38805849
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  • 4. Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides.
    Johnson CH, Karlsson E, Sarda S, Iddon L, Iqbal M, Meng X, Harding JR, Stachulski AV, Nicholson JK, Wilson ID, Lindon JC.
    Xenobiotica; 2010 Jan 15; 40(1):9-23. PubMed ID: 19919325
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  • 5. NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues.
    Johnson CH, Wilson ID, Harding JR, Stachulski AV, Iddon L, Nicholson JK, Lindon JC.
    Anal Chem; 2007 Nov 15; 79(22):8720-7. PubMed ID: 17944439
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  • 9. Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Walker GS, Atherton J, Bauman J, Kohl C, Lam W, Reily M, Lou Z, Mutlib A.
    Chem Res Toxicol; 2007 Jun 15; 20(6):876-86. PubMed ID: 17536843
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  • 10. Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions.
    Johnson CH, Athersuch TJ, Wilson ID, Iddon L, Meng X, Stachulski AV, Lindon JC, Nicholson JK.
    Anal Chem; 2008 Jul 01; 80(13):4886-95. PubMed ID: 18470997
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  • 11. Studies on the stereoselective internal acyl migration of ketoprofen glucuronides using 13C labeling and nuclear magnetic resonance spectroscopy.
    Akira K, Taira T, Hasegawa H, Sakuma C, Shinohara Y.
    Drug Metab Dispos; 1998 May 01; 26(5):457-64. PubMed ID: 9571227
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  • 12. Kinetics of intramolecular acyl migration of 1beta-O-acyl glucuronides of (R)- and (S)-2-phenylpropionic acids.
    Hasegawa H, Akira K, Shinohara Y, Kasuya Y, Hashimoto T.
    Biol Pharm Bull; 2001 Jul 01; 24(7):852-5. PubMed ID: 11456131
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  • 13. NMR spectroscopic and theoretical chemistry studies on the internal acyl migration reactions of the 1-O-acyl-beta-D-glucopyranuronate conjugates of 2-, 3-, and 4-(trifluoromethyl) benzoic acids.
    Nicholls AW, Akira K, Lindon JC, Farrant RD, Wilson ID, Harding J, Killick DA, Nicholson JK.
    Chem Res Toxicol; 1996 Dec 01; 9(8):1414-24. PubMed ID: 8951247
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  • 14. Rapid internal acyl migration and protein binding of synthetic probenecid glucuronides.
    Akira K, Uchijima T, Hashimoto T.
    Chem Res Toxicol; 2002 Jun 01; 15(6):765-72. PubMed ID: 12067243
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  • 16. Kinetic studies on the intramolecular acyl migration of beta-1-O-acyl glucuronides: application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy.
    Skordi E, Wilson ID, Lindon JC, Nicholson JK.
    Xenobiotica; 2005 Jul 01; 35(7):715-25. PubMed ID: 16316930
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  • 17. Measurement of Internal Acyl Migration Reaction Kinetics Using Directly Coupled HPLC-NMR:  Application for the Positional Isomers of Synthetic (2-Fluorobenzoyl)-d-glucopyranuronic Acid.
    Sidelmann UG, Hansen SH, Gavaghan C, Carless HA, Lindon JC, Farrant RD, Wilson ID, Nicholson JK.
    Anal Chem; 1996 Aug 01; 68(15):2564-72. PubMed ID: 21619203
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  • 18. S-naproxen-beta-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-1H NMR and high-performance liquid chromatography-UV.
    Mortensen RW, Corcoran O, Cornett C, Sidelmann UG, Lindon JC, Nicholson JK, Hansen SH.
    Drug Metab Dispos; 2001 Apr 01; 29(4 Pt 1):375-80. PubMed ID: 11259319
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  • 19. Nuclear magnetic resonance (NMR) and quantitative structure-activity relationship (QSAR) studies on the transacylation reactivity of model 1beta-O-acyl glucuronides. II: QSAR modelling of the reaction using both computational and experimental NMR parameters.
    Vanderhoeven SJ, Troke J, Tranter GE, Wilson ID, Nicholson JK, Lindon JC.
    Xenobiotica; 2004 Oct 01; 34(10):889-900. PubMed ID: 15764409
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  • 20. Chemistry and reactivity of acyl glucuronides.
    Stachulski AV.
    Curr Drug Metab; 2011 Mar 01; 12(3):215-21. PubMed ID: 20946098
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