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443 related items for PubMed ID: 19520915
1. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S. Am J Respir Cell Mol Biol; 2010 May; 42(5):524-36. PubMed ID: 19520915 [Abstract] [Full Text] [Related]
2. Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity. Williamson TP, Johnson DA, Johnson JA. Neurotoxicology; 2012 Jun; 33(3):272-9. PubMed ID: 22342405 [Abstract] [Full Text] [Related]
3. Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2. Singh A, Rangasamy T, Thimmulappa RK, Lee H, Osburn WO, Brigelius-Flohé R, Kensler TW, Yamamoto M, Biswal S. Am J Respir Cell Mol Biol; 2006 Dec; 35(6):639-50. PubMed ID: 16794261 [Abstract] [Full Text] [Related]
4. Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress. Yonchuk JG, Foley JP, Bolognese BJ, Logan G, Wixted WE, Kou JP, Chalupowicz DG, Feldser HG, Sanchez Y, Nie H, Callahan JF, Kerns JK, Podolin PL. J Pharmacol Exp Ther; 2017 Oct; 363(1):114-125. PubMed ID: 28790194 [Abstract] [Full Text] [Related]
6. Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, Singh A, Chen L, Zhuang X, Hogg J, Pare P, Tuder RM, Biswal S. Am J Respir Crit Care Med; 2008 Sep 15; 178(6):592-604. PubMed ID: 18556627 [Abstract] [Full Text] [Related]
7. Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke. Messier EM, Bahmed K, Tuder RM, Chu HW, Bowler RP, Kosmider B. Cell Death Dis; 2013 Apr 04; 4(4):e573. PubMed ID: 23559007 [Abstract] [Full Text] [Related]
8. Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury. Gao W, Yuan C, Zhang J, Li L, Yu L, Wiegman CH, Barnes PJ, Adcock IM, Huang M, Yao X. Clin Sci (Lond); 2015 Dec 04; 129(12):1011-23. PubMed ID: 26201096 [Abstract] [Full Text] [Related]
9. Nrf2: friend and foe in preventing cigarette smoking-dependent lung disease. Müller T, Hengstermann A. Chem Res Toxicol; 2012 Sep 17; 25(9):1805-24. PubMed ID: 22686525 [Abstract] [Full Text] [Related]
10. Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells. Kode A, Rajendrasozhan S, Caito S, Yang SR, Megson IL, Rahman I. Am J Physiol Lung Cell Mol Physiol; 2008 Mar 17; 294(3):L478-88. PubMed ID: 18162601 [Abstract] [Full Text] [Related]
11. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species. Reisman SA, Yeager RL, Yamamoto M, Klaassen CD. Toxicol Sci; 2009 Mar 17; 108(1):35-47. PubMed ID: 19129213 [Abstract] [Full Text] [Related]
12. Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers. Mercado N, Kizawa Y, Ueda K, Xiong Y, Kimura G, Moses A, Curtis JM, Ito K, Barnes PJ. PLoS One; 2014 Mar 17; 9(2):e88168. PubMed ID: 24505412 [Abstract] [Full Text] [Related]
13. Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2). Li W, Liu H, Zhou JS, Cao JF, Zhou XB, Choi AM, Chen ZH, Shen HH. J Biol Chem; 2012 Jun 15; 287(25):20922-30. PubMed ID: 22547061 [Abstract] [Full Text] [Related]
14. (-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD. Tian X, Xue Y, Xie G, Zhou Y, Xiao H, Ding F, Zhang M. Toxicol Appl Pharmacol; 2021 Oct 15; 429():115674. PubMed ID: 34403689 [Abstract] [Full Text] [Related]
15. Keap1-Nrf2 activation in the presence and absence of DJ-1. Gan L, Johnson DA, Johnson JA. Eur J Neurosci; 2010 Mar 15; 31(6):967-77. PubMed ID: 20377612 [Abstract] [Full Text] [Related]
16. Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. Singh A, Ling G, Suhasini AN, Zhang P, Yamamoto M, Navas-Acien A, Cosgrove G, Tuder RM, Kensler TW, Watson WH, Biswal S. Free Radic Biol Med; 2009 Feb 01; 46(3):376-86. PubMed ID: 19027064 [Abstract] [Full Text] [Related]
17. Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. Zhang P, Singh A, Yegnasubramanian S, Esopi D, Kombairaju P, Bodas M, Wu H, Bova SG, Biswal S. Mol Cancer Ther; 2010 Feb 01; 9(2):336-46. PubMed ID: 20124447 [Abstract] [Full Text] [Related]
18. Nrf2 protects against furosemide-induced hepatotoxicity. Qu Q, Liu J, Zhou HH, Klaassen CD. Toxicology; 2014 Oct 03; 324():35-42. PubMed ID: 24813929 [Abstract] [Full Text] [Related]
19. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response. Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD. Mol Cell Biol; 2011 May 03; 31(9):1800-11. PubMed ID: 21383067 [Abstract] [Full Text] [Related]
20. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, Yamamoto M. Proc Natl Acad Sci U S A; 2012 Aug 21; 109(34):13561-6. PubMed ID: 22872865 [Abstract] [Full Text] [Related] Page: [Next] [New Search]