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Journal Abstract Search

213 related items for PubMed ID: 19523528

  • 1. Assessment of the pharmacological effects of inotropic drugs on left ventricular pressure and contractility: an evaluation of the QA interval as an indirect indicator of cardiac inotropism.
    Norton K, Iacono G, Vezina M.
    J Pharmacol Toxicol Methods; 2009; 60(2):193-7. PubMed ID: 19523528
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  • 3. An evaluation of the utility of LVdP/dt40, QA interval, LVdP/dtmin and Tau as indicators of drug-induced changes in contractility and lusitropy in dogs.
    Pugsley MK, Guth B, Chiang AY, Doyle JM, Engwall M, Guillon JM, Hoffmann PK, Koerner JE, Mittelstadt SW, Pierson JB, Rossman EI, Sarazan DR, Parish ST.
    J Pharmacol Toxicol Methods; 2017; 85():1-21. PubMed ID: 28065821
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  • 4. A translational assessment of preclinical versus clinical tools for the measurement of cardiac contractility: comparison of LV dP/dt(max) with echocardiography in telemetry implanted beagle dogs.
    Cools F, Dhuyvetter D, Vanlommel A, Janssens S, Borghys H, Geys H, Gallacher DJ.
    J Pharmacol Toxicol Methods; 2014; 69(1):17-23. PubMed ID: 24140387
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  • 5. The effects of housing conditions on baseline cardiovascular parameters and the sensitivity to detect changes in contractility in telemetry-implanted dogs.
    Sadekova N, Boudreau G, Jalbert B, Norton K.
    J Pharmacol Toxicol Methods; 2016; 81():60-74. PubMed ID: 27163176
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  • 6. Evaluation of cardiac function in unrestrained dogs and monkeys using left ventricular dP/dt.
    Buchanan LV, Warner WA, Arthur SR, Gleason CR, Lewen G, Levesque PC, Gill MW.
    J Pharmacol Toxicol Methods; 2016; 80():51-8. PubMed ID: 27063376
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  • 8. The value added by measuring myocardial contractility 'in vivo' in safety pharmacological profiling of drug candidates.
    Markert M, Klumpp A, Trautmann T, Mayer K, Stubhan M, Guth B.
    J Pharmacol Toxicol Methods; 2007; 56(2):203-11. PubMed ID: 17583538
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  • 9. Evaluation of a method to correct the contractility index LVdP/dt(max) for changes in heart rate.
    Markert M, Trautmann T, Groß M, Ege A, Mayer K, Guth B.
    J Pharmacol Toxicol Methods; 2012 Sep; 66(2):98-105. PubMed ID: 22554385
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  • 10. QA interval as an indirect measure of cardiac contractility in the conscious telemeterised rat: model optimisation and evaluation.
    Adeyemi O, Roberts S, Harris J, West H, Shome S, Dewhurst M.
    J Pharmacol Toxicol Methods; 2009 Sep; 60(2):159-66. PubMed ID: 19616109
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  • 11. Left ventricular pressure, contractility and dP/dt(max) in nonclinical drug safety assessment studies.
    Sarazan RD, Kroehle JP, Main BW.
    J Pharmacol Toxicol Methods; 2012 Sep; 66(2):71-8. PubMed ID: 22659561
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  • 12. Characterization of an investigative safety pharmacology model to assess comprehensive cardiac function and structure in chronically instrumented conscious beagle dogs.
    Regan CP, Stump GL, Detwiler TJ, Chen L, Regan HK, Gilberto DB, DeGeorge JJ, Sannajust FJ.
    J Pharmacol Toxicol Methods; 2016 Sep; 81():107-14. PubMed ID: 27166580
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  • 13. Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.
    Rossman EI, Cools F, Cordes J, Dhuyvetter D, Doyle JM, Friedrichs GS, Guth B, Neradilek MB, Parish ST, Pierson JB, Polissar N, Tang HM.
    J Pharmacol Toxicol Methods; 2020 Sep; 105():106897. PubMed ID: 32663523
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  • 14. The evaluation of drug-induced changes in left ventricular function in pentobarbital-anesthetized dogs.
    Koshman YE, Herzberg BR, Seifert TR, Polakowski JS, Mittelstadt SW.
    J Pharmacol Toxicol Methods; 2018 Sep; 91():27-35. PubMed ID: 29330133
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  • 15. Translational assessment of cardiac contractility by echocardiography in the telemetered rat.
    Tang HM, Ju H, Zhao S, LaDuke C, Hahn S, Glick J, Carey C, Friedrichs GS.
    J Pharmacol Toxicol Methods; 2016 Sep; 77():24-32. PubMed ID: 26427954
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  • 16. Optimising conditions for studying the acute effects of drugs on indices of cardiac contractility and on haemodynamics in anaesthetized guinea pigs.
    Mooney L, Marks L, Philp KL, Skinner M, Coker SJ, Currie S.
    J Pharmacol Toxicol Methods; 2012 Jul; 66(1):43-51. PubMed ID: 22659057
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  • 18. Positive chronotropic and inotropic effects of pimobendan (UD-CG 115 BS) in isolated, cross-circulated canine heart preparations.
    Furukawa Y, Akahane K, Ogiwara Y, Haniuda M, Chiba S.
    Arch Int Pharmacodyn Ther; 1989 Jul; 300():159-73. PubMed ID: 2575887
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  • 19. Cardiovascular parameters in anaesthetized guinea pigs: a safety pharmacology screening model.
    Hauser DS, Stade M, Schmidt A, Hanauer G.
    J Pharmacol Toxicol Methods; 2005 Jul; 52(1):106-14. PubMed ID: 15961325
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