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345 related items for PubMed ID: 19524054
1. Models of torsades de pointes: effects of FPL64176, DPI201106, dofetilide, and chromanol 293B in isolated rabbit and guinea pig hearts. Cheng HC, Incardona J. J Pharmacol Toxicol Methods; 2009; 60(2):174-84. PubMed ID: 19524054 [Abstract] [Full Text] [Related]
2. New in vitro model for proarrhythmia safety screening: IKs inhibition potentiates the QTc prolonging effect of IKr inhibitors in isolated guinea pig hearts. Kui P, Orosz S, Takács H, Sarusi A, Csík N, Rárosi F, Csekő C, Varró A, Papp JG, Forster T, Farkas AS, Farkas A. J Pharmacol Toxicol Methods; 2016; 80():26-34. PubMed ID: 27063345 [Abstract] [Full Text] [Related]
3. Assessment of efficacy of proarrhythmia biomarkers in isolated rabbit hearts with attenuated repolarization reserve. Orosz S, Sarusi A, Csík N, Papp JG, Varró A, Farkas S, Forster T, Farkas AS, Farkas A. J Cardiovasc Pharmacol; 2014 Sep; 64(3):266-76. PubMed ID: 24887684 [Abstract] [Full Text] [Related]
4. [Anti-arrhythmic effects of taurine-magnesium coordination compound on torsades de pointes]. Li Y, Sun K, An MY, Pan YY, Sun T, Yin YQ, Kang Y, Lou JS. Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2018 Feb 08; 34(2):106-110. PubMed ID: 29926671 [Abstract] [Full Text] [Related]
5. Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit. Jacobson I, Carlsson L, Duker G. J Pharmacol Toxicol Methods; 2011 Feb 08; 63(1):40-6. PubMed ID: 20451633 [Abstract] [Full Text] [Related]
6. The role of the Na+/Ca2+ exchanger, I(Na) and I(CaL) in the genesis of dofetilide-induced torsades de pointes in isolated, AV-blocked rabbit hearts. Farkas AS, Makra P, Csík N, Orosz S, Shattock MJ, Fülöp F, Forster T, Csanády M, Papp JG, Varró A, Farkas A. Br J Pharmacol; 2009 Mar 08; 156(6):920-32. PubMed ID: 19222480 [Abstract] [Full Text] [Related]
7. Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes. Lengyel C, Varró A, Tábori K, Papp JG, Baczkó I. Br J Pharmacol; 2007 Aug 08; 151(7):941-51. PubMed ID: 17533421 [Abstract] [Full Text] [Related]
8. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel. Davie C, Pierre-Valentin J, Pollard C, Standen N, Mitcheson J, Alexander P, Thong B. J Cardiovasc Electrophysiol; 2004 Nov 08; 15(11):1302-9. PubMed ID: 15574182 [Abstract] [Full Text] [Related]
9. Slow delayed rectifier K+ current block by HMR 1556 increases dispersion of repolarization and promotes Torsades de Pointes in rabbit ventricles. So PP, Backx PH, Dorian P. Br J Pharmacol; 2008 Dec 08; 155(8):1185-94. PubMed ID: 18836478 [Abstract] [Full Text] [Related]
10. Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits. Huang ZJ, Dai DZ, Li N, Na T, Ji M, Dai Y. Clin Exp Pharmacol Physiol; 2007 Apr 08; 34(4):310-7. PubMed ID: 17324143 [Abstract] [Full Text] [Related]
11. Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart. Guérard NC, Traebert M, Suter W, Dumotier BM. J Pharmacol Toxicol Methods; 2008 Apr 08; 58(1):32-40. PubMed ID: 18582585 [Abstract] [Full Text] [Related]
12. Isolated perfused and paced guinea pig heart to test for drug-induced changes of the QT interval. Cheng HC, Incardona J, McCullough B. J Pharmacol Toxicol Methods; 2006 Apr 08; 54(3):278-87. PubMed ID: 16507347 [Abstract] [Full Text] [Related]
17. Differential effect of beta-adrenergic stimulation on the frequency-dependent electrophysiologic actions of the new class III antiarrhythmics dofetilide, ambasilide, and chromanol 293B. Schreieck J, Wang Y, Gjini V, Korth M, Zrenner B, Schömig A, Schmitt C. J Cardiovasc Electrophysiol; 1997 Dec 08; 8(12):1420-30. PubMed ID: 9436780 [Abstract] [Full Text] [Related]
19. How to determine cardiac ion channels targeted by drugs using the isolated rabbit ventricular wedge model. Liu G, Liu T, Cohen D, Liu T, Yan GX. J Pharmacol Toxicol Methods; 2016 Dec 08; 81():161-70. PubMed ID: 27195944 [Abstract] [Full Text] [Related]
20. Importance of extracardiac alpha1-adrenoceptor stimulation in assisting dofetilide to induce torsade de pointes in rabbit hearts. Farkas AS, Acsai K, Tóth A, Dézsi L, Orosz S, Forster T, Csanády M, Papp JG, Varró A, Farkas A. Eur J Pharmacol; 2006 May 10; 537(1-3):118-25. PubMed ID: 16618484 [Abstract] [Full Text] [Related] Page: [Next] [New Search]