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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

114 related items for PubMed ID: 19537798

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  • 4. The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
    Varty GB, Lu SX, Morgan CA, Cohen-Williams ME, Hodgson RA, Smith-Torhan A, Zhang H, Fawzi AB, Graziano MP, Ho GD, Matasi J, Tulshian D, Coffin VL, Carey GJ.
    J Pharmacol Exp Ther; 2008 Aug; 326(2):672-82. PubMed ID: 18492950
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  • 8. 2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.
    Kobayashi K, Uchiyama M, Takahashi H, Kawamoto H, Ito S, Yoshizumi T, Nakashima H, Kato T, Shimizu A, Yamamoto I, Asai M, Miyazoe H, Ohno A, Hirayama M, Ozaki S, Tani T, Ishii Y, Tanaka T, Mochidome T, Tadano K, Fukuroda T, Ohta H, Okamoto O.
    Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3096-9. PubMed ID: 19394217
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  • 10. Discovery of the first small-molecule opioid pan antagonist with nanomolar affinity at mu, delta, kappa, and nociceptin opioid receptors.
    Zaveri NT, Journigan VB, Polgar WE.
    ACS Chem Neurosci; 2015 Apr 15; 6(4):646-57. PubMed ID: 25635572
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  • 11. Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats.
    Teshima K, Minoguchi M, Tounai S, Ashimori A, Eguchi J, Allen CN, Shibata S.
    Br J Pharmacol; 2005 Sep 15; 146(1):33-40. PubMed ID: 15980870
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  • 12. Novel ORL1-selective antagonists with oral bioavailability and brain penetrability.
    Okamoto O, Kobayashi K, Kawamoto H, Ito S, Yoshizumi T, Yamamoto I, Hashimoto M, Shimizu A, Takahashi H, Ishii Y, Ozaki S, Ohta H.
    Bioorg Med Chem Lett; 2008 Jun 01; 18(11):3282-5. PubMed ID: 18448337
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  • 17. Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity.
    Goto Y, Arai-Otsuki S, Tachibana Y, Ichikawa D, Ozaki S, Takahashi H, Iwasawa Y, Okamoto O, Okuda S, Ohta H, Sagara T.
    J Med Chem; 2006 Feb 09; 49(3):847-9. PubMed ID: 16451050
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  • 18. Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor.
    Chang SD, Mascarella SW, Spangler SM, Gurevich VV, Navarro HA, Carroll FI, Bruchas MR.
    Mol Pharmacol; 2015 Sep 09; 88(3):502-11. PubMed ID: 26134494
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  • 20. The opioid receptor like-1 receptor agonist Ro 64-6198 (1S,3aS-8-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one) produces a discriminative stimulus in rats distinct from that of a mu, kappa, and delta opioid receptor agonist cue.
    Recker MD, Higgins GA.
    J Pharmacol Exp Ther; 2004 Nov 09; 311(2):652-8. PubMed ID: 15226383
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