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Journal Abstract Search

201 related items for PubMed ID: 19552464

  • 1. Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine.
    Winkler JD, Isaacs A, Holderbaum L, Tatard V, Dahmane N.
    Org Lett; 2009 Jul 02; 11(13):2824-7. PubMed ID: 19552464
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  • 2. Exo-cyclopamine--a stable and potent inhibitor of hedgehog-signaling.
    Heretsch P, Büttner A, Tzagkaroulaki L, Zahn S, Kirchner B, Giannis A.
    Chem Commun (Camb); 2011 Jul 14; 47(26):7362-4. PubMed ID: 21589966
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  • 4. Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport.
    Incardona JP, Gaffield W, Lange Y, Cooney A, Pentchev PG, Liu S, Watson JA, Kapur RP, Roelink H.
    Dev Biol; 2000 Aug 15; 224(2):440-52. PubMed ID: 10926779
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  • 9. Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition.
    El-Zaatari M, Grabowska AM, McKenzie AJ, Powe DG, Scotting PJ, Watson SA.
    Regul Pept; 2008 Feb 07; 146(1-3):131-9. PubMed ID: 17996964
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  • 10. From teratogens to potential therapeutics: natural inhibitors of the Hedgehog signaling network come of age.
    Hovhannisyan A, Matz M, Gebhardt R.
    Planta Med; 2009 Oct 07; 75(13):1371-80. PubMed ID: 19639534
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  • 12. Identification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signaling.
    Lipinski RJ, Dengler E, Kiehn M, Peterson RE, Bushman W.
    Toxicol Sci; 2007 Dec 07; 100(2):456-63. PubMed ID: 17728282
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  • 14. Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified.
    Wilson SR, Strand MF, Krapp A, Rise F, Petersen D, Krauss S.
    J Pharm Biomed Anal; 2010 Sep 05; 52(5):707-13. PubMed ID: 20236786
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  • 16. Inhibition of Sonic hedgehog signaling leads to posterior digit loss in Ambystoma mexicanum: parallels to natural digit reduction in urodeles.
    Stopper GF, Wagner GP.
    Dev Dyn; 2007 Jan 05; 236(1):321-31. PubMed ID: 17117438
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  • 17. Expression of sonic hedgehog signaling components in hepatocellular carcinoma and cyclopamine-induced apoptosis through Bcl-2 downregulation in vitro.
    Chen XL, Cheng QY, She MR, Wang Q, Huang XH, Cao LQ, Fu XH, Chen JS.
    Arch Med Res; 2010 Jul 05; 41(5):315-23. PubMed ID: 20851287
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  • 18. Synthesis and anticancer activity studies of cyclopamine derivatives.
    Zhang J, Garrossian M, Gardner D, Garrossian A, Chang YT, Kim YK, Chang CW.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1359-63. PubMed ID: 18221872
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  • 20. Hedgehog signaling in the murine melanoma microenvironment.
    Geng L, Cuneo KC, Cooper MK, Wang H, Sekhar K, Fu A, Hallahan DE.
    Angiogenesis; 2007 Feb 15; 10(4):259-67. PubMed ID: 17762973
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