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213 related items for PubMed ID: 19554557

  • 1. Computational determination of fundamental pathway and activation barriers for acetohydroxyacid synthase-catalyzed condensation reactions of alpha-keto acids.
    Xiong Y, Liu J, Yang GF, Zhan CG.
    J Comput Chem; 2010 Jun; 31(8):1592-602. PubMed ID: 19554557
    [Abstract] [Full Text] [Related]

  • 2. Significant catalytic roles for Glu47 and Gln 110 in all four of the C-C bond-making and -breaking steps of the reactions of acetohydroxyacid synthase II.
    Vyazmensky M, Steinmetz A, Meyer D, Golbik R, Barak Z, Tittmann K, Chipman DM.
    Biochemistry; 2011 Apr 19; 50(15):3250-60. PubMed ID: 21370850
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  • 3. Structural and functional evaluation of three well-conserved serine residues in tobacco acetohydroxyacid synthase.
    Yoon MY, Gedi V, Kim J, Park Y, Kim DE, Park EH, Choi JD.
    Biochimie; 2010 Jan 19; 92(1):65-70. PubMed ID: 19825392
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  • 4. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I.
    Belenky I, Steinmetz A, Vyazmensky M, Barak Z, Tittmann K, Chipman DM.
    FEBS J; 2012 Jun 19; 279(11):1967-79. PubMed ID: 22443469
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  • 5. Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors.
    Choi KJ, Noh KM, Kim DE, Ha BH, Kim EE, Yoon MY.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):24-30. PubMed ID: 17718999
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  • 6. Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme.
    Tittmann K, Schröder K, Golbik R, McCourt J, Kaplun A, Duggleby RG, Barak Z, Chipman DM, Hübner G.
    Biochemistry; 2004 Jul 13; 43(27):8652-61. PubMed ID: 15236573
    [Abstract] [Full Text] [Related]

  • 7. Homology modeling of the structure of bacterial acetohydroxy acid synthase and examination of the active site by site-directed mutagenesis.
    Ibdah M, Bar-Ilan A, Livnah O, Schloss JV, Barak Z, Chipman DM.
    Biochemistry; 1996 Dec 17; 35(50):16282-91. PubMed ID: 8973202
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  • 8. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.
    Choi KJ, Yu YG, Hahn HG, Choi JD, Yoon MY.
    FEBS Lett; 2005 Aug 29; 579(21):4903-10. PubMed ID: 16111681
    [Abstract] [Full Text] [Related]

  • 9. A QM/MM study on the reaction pathway leading to 2-aceto-2-hydroxybutyrate in the catalytic cycle of AHAS.
    Sánchez L, Jaña GA, Delgado EJ.
    J Comput Chem; 2014 Mar 05; 35(6):488-94. PubMed ID: 24395707
    [Abstract] [Full Text] [Related]

  • 10. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 05; 95(7):1411-21. PubMed ID: 23523771
    [Abstract] [Full Text] [Related]

  • 11. The carboligation reaction of acetohydroxyacid synthase II: steady-state intermediate distributions in wild type and mutants by NMR.
    Tittmann K, Vyazmensky M, Hübner G, Barak Z, Chipman DM.
    Proc Natl Acad Sci U S A; 2005 Jan 18; 102(3):553-8. PubMed ID: 15640355
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  • 13. Identification of some novel AHAS inhibitors via molecular docking and virtual screening approach.
    Wang JG, Xiao YJ, Li YH, Ma Y, Li ZM.
    Bioorg Med Chem; 2007 Jan 01; 15(1):374-80. PubMed ID: 17049866
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  • 15. Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.
    Pang SS, Duggleby RG, Guddat LW.
    J Mol Biol; 2002 Mar 22; 317(2):249-62. PubMed ID: 11902841
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  • 18. Bacterial acetohydroxyacid synthase and its inhibitors--a summary of their structure, biological activity and current status.
    Gedi V, Yoon MY.
    FEBS J; 2012 Mar 22; 279(6):946-63. PubMed ID: 22284339
    [Abstract] [Full Text] [Related]

  • 19. How an enzyme answers multiple-choice questions.
    McCourt JA, Duggleby RG.
    Trends Biochem Sci; 2005 May 22; 30(5):222-5. PubMed ID: 15896736
    [Abstract] [Full Text] [Related]

  • 20. Chemical synthesis, in vitro acetohydroxyacid synthase (AHAS) inhibition, herbicidal activity, and computational studies of isatin derivatives.
    Wang J, Tan H, Li Y, Ma Y, Li Z, Guddat LW.
    J Agric Food Chem; 2011 Sep 28; 59(18):9892-900. PubMed ID: 21838297
    [Abstract] [Full Text] [Related]

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