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91 related items for PubMed ID: 19573588

  • 1. Oral small-molecule tyrosine kinase inhibitor midostaurin (PKC412) inhibits growth and induces megakaryocytic differentiation in human leukemia cells.
    Huang YC, Chao DK, Clifford Chao KS, Chen YJ.
    Toxicol In Vitro; 2009 Sep; 23(6):979-85. PubMed ID: 19573588
    [Abstract] [Full Text] [Related]

  • 2. Staurosporine induces megakaryocytic differentiation through the upregulation of JAK/Stat3 signaling pathway.
    Peng HY, Liao HF.
    Ann Hematol; 2011 Sep; 90(9):1017-29. PubMed ID: 21331591
    [Abstract] [Full Text] [Related]

  • 3. Midostaurin (PKC412) modulates differentiation and maturation of human myeloid dendritic cells.
    Huang YC, Shieh HR, Chen YJ.
    Toxicol In Vitro; 2010 Sep; 24(6):1705-10. PubMed ID: 20685248
    [Abstract] [Full Text] [Related]

  • 4. Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cells.
    Quentmeier H, Zaborski M, Graf G, Ludwig WD, Drexler HG.
    Leukemia; 1996 Feb; 10(2):297-310. PubMed ID: 8637239
    [Abstract] [Full Text] [Related]

  • 5. The alpha1-adrenergic receptor antagonists, benoxathian and prazosin, induce apoptosis and a switch towards megakaryocytic differentiation in human erythroleukemia cells.
    Fuchs R, Stelzer I, Haas HS, Leitinger G, Schauenstein K, Sadjak A.
    Ann Hematol; 2009 Oct; 88(10):989-97. PubMed ID: 19241077
    [Abstract] [Full Text] [Related]

  • 6. ETV6-NTRK3 as a therapeutic target of small molecule inhibitor PKC412.
    Chi HT, Ly BT, Kano Y, Tojo A, Watanabe T, Sato Y.
    Biochem Biophys Res Commun; 2012 Dec 07; 429(1-2):87-92. PubMed ID: 23131561
    [Abstract] [Full Text] [Related]

  • 7. Erythroid and megakaryocytic differentiation of K562 erythroleukemic cells by monochloramine.
    Ogino T, Kobuchi H, Fujita H, Matsukawa A, Utsumi K.
    Free Radic Res; 2014 Mar 07; 48(3):292-302. PubMed ID: 24237253
    [Abstract] [Full Text] [Related]

  • 8. Antileukemic effects of midostaurin in acute myeloid leukemia - the possible importance of multikinase inhibition in leukemic as well as nonleukemic stromal cells.
    Tvedt TH, Nepstad I, Bruserud Ø.
    Expert Opin Investig Drugs; 2017 Mar 07; 26(3):343-355. PubMed ID: 28001095
    [Abstract] [Full Text] [Related]

  • 9. Use of human leukemia-lymphoma cell lines in hematological research: effects of thrombopoietin on human leukemia cell lines.
    Drexler HG, Quentmeier H.
    Hum Cell; 1996 Dec 07; 9(4):309-16. PubMed ID: 9183663
    [Abstract] [Full Text] [Related]

  • 10. Naturally Occurring Bicoumarin Compound Daphnoretin Inhibits Growth and Induces Megakaryocytic Differentiation in Human Chronic Myeloid Leukemia Cells.
    Huang YC, Huang CP, Lin CP, Yang KC, Lei YJ, Wang HP, Kuo YH, Chen YJ.
    Cells; 2022 Oct 16; 11(20):. PubMed ID: 36291120
    [Abstract] [Full Text] [Related]

  • 11. Levels of Smad7 regulate Smad and mitogen activated kinases (MAPKs) signaling and controls erythroid and megakaryocytic differentiation of erythroleukemia cells.
    Akel S, Bertolette D, Petrow-Sadowski C, Ruscetti FW.
    Platelets; 2007 Dec 16; 18(8):566-78. PubMed ID: 18041647
    [Abstract] [Full Text] [Related]

  • 12. Involvement of nPKC-MAPK pathway in the decrease of nucleophosmin/B23 during megakaryocytic differentiation of human myelogenous leukemia K562 cells.
    Chou CC, Yung BY, Hsu CY.
    Life Sci; 2007 May 08; 80(22):2051-9. PubMed ID: 17448503
    [Abstract] [Full Text] [Related]

  • 13. Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells.
    Huang HL, Chen YC, Huang YC, Yang KC, Pan Hy, Shih SP, Chen YJ.
    PLoS One; 2011 May 08; 6(12):e29014. PubMed ID: 22216158
    [Abstract] [Full Text] [Related]

  • 14. Effects of chebulinic acid on differentiation of human leukemia K562 cells.
    Yi ZC, Wang Z, Li HX, Liu MJ, Wu RC, Wang XH.
    Acta Pharmacol Sin; 2004 Feb 08; 25(2):231-8. PubMed ID: 14769215
    [Abstract] [Full Text] [Related]

  • 15. In vitro dual effect of arsenic trioxide on hemopoiesis: inhibition of erythropoiesis and stimulation of megakaryocytic maturation.
    Saulle E, Riccioni R, Pelosi E, Stafness M, Mariani G, De Tuglie G, Peschle C, Testa U.
    Blood Cells Mol Dis; 2006 Feb 08; 36(1):59-76. PubMed ID: 16360329
    [Abstract] [Full Text] [Related]

  • 16. Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells.
    Stölzel F, Steudel C, Oelschlägel U, Mohr B, Koch S, Ehninger G, Thiede C.
    Ann Hematol; 2010 Jul 08; 89(7):653-62. PubMed ID: 20119833
    [Abstract] [Full Text] [Related]

  • 17. Expression of protease activated receptor 3 (PAR3) is upregulated by induction of megakaryocyte phenotype in human erythroleukemia (HEL) cells.
    Cupit LD, Schmidt VA, Gnatenko DV, Bahou WF.
    Exp Hematol; 2004 Oct 08; 32(10):991-9. PubMed ID: 15504554
    [Abstract] [Full Text] [Related]

  • 18. A natural small molecule induces megakaryocytic differentiation and suppresses leukemogenesis through activation of PKCδ/ERK1/2 signaling pathway in erythroleukemia cells.
    Yang J, Qiu J, Hu Y, Zhang Y, Chen L, Long Q, Chen J, Song J, Rao Q, Li Y, Gu W, Hao X.
    Biomed Pharmacother; 2019 Oct 08; 118():109265. PubMed ID: 31545282
    [Abstract] [Full Text] [Related]

  • 19. Thrombopoietin: expression of its receptor MPL and proliferative effects on leukemic cells.
    Drexler HG, Quentmeier H.
    Leukemia; 1996 Sep 08; 10(9):1405-21. PubMed ID: 8751457
    [Abstract] [Full Text] [Related]

  • 20. 2-(trimethylammonium)ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate promotes megakaryocytic differentiation of myeloid leukaemia cells and primary human CD34⁺ haematopoietic stem cells.
    Limb JK, Song D, Jeon M, Han SY, Han G, Jhon GJ, Bae YS, Kim J.
    J Tissue Eng Regen Med; 2015 Apr 08; 9(4):435-46. PubMed ID: 23166016
    [Abstract] [Full Text] [Related]

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