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Journal Abstract Search

558 related items for PubMed ID: 19574054

  • 1. Synthesis, antimalarial activity and cytotoxicity of substituted 3,6-diphenyl-[1,2,4,5]tetraoxanes.
    Kumar N, Khan SI, Beena, Rajalakshmi G, Kumaradhas P, Rawat DS.
    Bioorg Med Chem; 2009 Aug 01; 17(15):5632-8. PubMed ID: 19574054
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, thermal stability, antimalarial activity of symmetrically and asymmetrically substituted tetraoxanes.
    Atheaya H, Khan SI, Mamgain R, Rawat DS.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1446-9. PubMed ID: 18248990
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and antimalarial activity of dihydroperoxides and tetraoxanes conjugated with bis(benzyl)acetone derivatives.
    Franco LL, de Almeida MV, E Silva LF, Vieira PP, Pohlit AM, Valle MS.
    Chem Biol Drug Des; 2012 May 15; 79(5):790-7. PubMed ID: 22284812
    [Abstract] [Full Text] [Related]

  • 4. Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
    Ellis GL, Amewu R, Sabbani S, Stocks PA, Shone A, Stanford D, Gibbons P, Davies J, Vivas L, Charnaud S, Bongard E, Hall C, Rimmer K, Lozanom S, Jesús M, Gargallo D, Ward SA, O'Neill PM.
    J Med Chem; 2008 Apr 10; 51(7):2170-7. PubMed ID: 18341274
    [Abstract] [Full Text] [Related]

  • 5. The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone.
    Dong Y, McCullough KJ, Wittlin S, Chollet J, Vennerstrom JL.
    Bioorg Med Chem Lett; 2010 Nov 15; 20(22):6359-61. PubMed ID: 20943385
    [Abstract] [Full Text] [Related]

  • 6. Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials.
    Opsenica I, Opsenica D, Smith KS, Milhous WK, Solaja BA.
    J Med Chem; 2008 Apr 10; 51(7):2261-6. PubMed ID: 18330976
    [Abstract] [Full Text] [Related]

  • 7. Influence of stereoisomer of dispiro-1,2,4,5-tetraoxanes on their binding mode with heme and on antimalarial activity: molecular docking studies.
    Tonmunphean S, Wijitkosoom A, Tantirungrotechai Y.
    Bioorg Med Chem; 2004 May 01; 12(9):2005-12. PubMed ID: 15080904
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups.
    Dong Y, Matile H, Chollet J, Kaminsky R, Wood JK, Vennerstrom JL.
    J Med Chem; 1999 Apr 22; 42(8):1477-80. PubMed ID: 10212135
    [Abstract] [Full Text] [Related]

  • 9. New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton.
    Opsenica I, Opsenica D, Lanteri CA, Anova L, Milhous WK, Smith KS, Solaja BA.
    J Med Chem; 2008 Oct 09; 51(19):6216-9. PubMed ID: 18774792
    [Abstract] [Full Text] [Related]

  • 10. Iodine-catalyzed one-pot synthesis and antimalarial activity evaluation of symmetrically and asymmetrically substituted 3,6-diphenyl[1,2,4,5]tetraoxanes.
    Kumar N, Khan SI, Sharma M, Atheaya H, Rawat DS.
    Bioorg Med Chem Lett; 2009 Mar 15; 19(6):1675-7. PubMed ID: 19231182
    [Abstract] [Full Text] [Related]

  • 11. Tetraoxane antimalarials and their reaction with Fe(II).
    Opsenica I, Terzić N, Opsenica D, Angelovski G, Lehnig M, Eilbracht P, Tinant B, Juranić Z, Smith KS, Yang YS, Diaz DS, Smith PL, Milhous WK, Doković D, Solaja BA.
    J Med Chem; 2006 Jun 29; 49(13):3790-9. PubMed ID: 16789736
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
    Amewu RK, Chadwick J, Hussain A, Panda S, Rinki R, Janneh O, Ward SA, Miguel C, Burrell-Saward H, Vivas L, O'Neill PM.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7392-7. PubMed ID: 24148834
    [Abstract] [Full Text] [Related]

  • 13. Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives(1).
    Terzić N, Opsenica D, Milić D, Tinant B, Smith KS, Milhous WK, Solaja BA.
    J Med Chem; 2007 Oct 18; 50(21):5118-27. PubMed ID: 17887664
    [Abstract] [Full Text] [Related]

  • 14. Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
    O'Neill PM, Amewu RK, Nixon GL, Bousejra ElGarah F, Mungthin M, Chadwick J, Shone AE, Vivas L, Lander H, Barton V, Muangnoicharoen S, Bray PG, Davies J, Park BK, Wittlin S, Brun R, Preschel M, Zhang K, Ward SA.
    Angew Chem Int Ed Engl; 2010 Aug 02; 49(33):5693-7. PubMed ID: 20629058
    [No Abstract] [Full Text] [Related]

  • 15. Synthesis, antimalarial activity and cytotoxicity of 4-aminoquinoline-triazine conjugates.
    Manohar S, Khan SI, Rawat DS.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):322-5. PubMed ID: 19910192
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and in vitro antimalarial activity of tetraoxane-amine/amide conjugates.
    Kumar N, Khan SI, Atheaya H, Mamgain R, Rawat DS.
    Eur J Med Chem; 2011 Jul 01; 46(7):2816-27. PubMed ID: 21530018
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline.
    Delarue-Cochin S, Grellier P, Maes L, Mouray E, Sergheraert C, Melnyk P.
    Eur J Med Chem; 2008 Oct 01; 43(10):2045-55. PubMed ID: 18226428
    [Abstract] [Full Text] [Related]

  • 18. Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.
    Bousejra-El Garah F, Wong MH, Amewu RK, Muangnoicharoen S, Maggs JL, Stigliani JL, Park BK, Chadwick J, Ward SA, O'Neill PM.
    J Med Chem; 2011 Oct 13; 54(19):6443-55. PubMed ID: 21888440
    [Abstract] [Full Text] [Related]

  • 19. Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers).
    Dong Y, Creek D, Chollet J, Matile H, Charman SA, Wittlin S, Wood JK, Vennerstrom JL.
    Antimicrob Agents Chemother; 2007 Aug 13; 51(8):3033-5. PubMed ID: 17485500
    [Abstract] [Full Text] [Related]

  • 20. Tetraoxanes as antimalarials: harnessing the endoperoxide.
    Fisher LC, Blackie MA.
    Mini Rev Med Chem; 2014 Feb 13; 14(2):123-35. PubMed ID: 24456270
    [Abstract] [Full Text] [Related]

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