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183 related items for PubMed ID: 19578154

  • 1. Inhibition of p38-MAPK potentiates cisplatin-induced apoptosis via GSH depletion and increases intracellular drug accumulation in growth-arrested kidney tubular epithelial cells.
    Rodríguez-García ME, Quiroga AG, Castro J, Ortiz A, Aller P, Mata F.
    Toxicol Sci; 2009 Oct; 111(2):413-23. PubMed ID: 19578154
    [Abstract] [Full Text] [Related]

  • 2. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P.
    J Cell Physiol; 2006 Dec; 209(3):1006-15. PubMed ID: 16972261
    [Abstract] [Full Text] [Related]

  • 3. Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.
    Ramos AM, Aller P.
    Biochem Pharmacol; 2008 May 15; 75(10):1912-23. PubMed ID: 18359480
    [Abstract] [Full Text] [Related]

  • 4. Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
    Sánchez Y, Calle C, de Blas E, Aller P.
    Chem Biol Interact; 2009 Nov 10; 182(1):37-44. PubMed ID: 19720055
    [Abstract] [Full Text] [Related]

  • 5. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.
    Desbiens KM, Deschesnes RG, Labrie MM, Desfossés Y, Lambert H, Landry J, Bellmann K.
    Biochem J; 2003 Jun 01; 372(Pt 2):631-41. PubMed ID: 12646044
    [Abstract] [Full Text] [Related]

  • 6. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
    Hsu YL, Kuo PL, Lin LT, Lin CC.
    J Pharmacol Exp Ther; 2005 Apr 01; 313(1):333-44. PubMed ID: 15626723
    [Abstract] [Full Text] [Related]

  • 7. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
    Sánchez Y, Simón GP, Calviño E, de Blas E, Aller P.
    J Pharmacol Exp Ther; 2010 Oct 01; 335(1):114-23. PubMed ID: 20605902
    [Abstract] [Full Text] [Related]

  • 8. The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels.
    Han YH, Moon HJ, You BR, Kim SZ, Kim SH, Park WH.
    Anticancer Res; 2009 Oct 01; 29(10):3837-44. PubMed ID: 19846917
    [Abstract] [Full Text] [Related]

  • 9. The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
    Kang YH, Lee SJ.
    J Cell Physiol; 2008 Oct 01; 217(1):23-33. PubMed ID: 18412143
    [Abstract] [Full Text] [Related]

  • 10. Roles of mitogen-activated protein kinase pathways during Escherichia coli-induced apoptosis in U937 cells.
    Wang JH, Zhou YJ, He P, Chen BY.
    Apoptosis; 2007 Feb 01; 12(2):375-85. PubMed ID: 17191113
    [Abstract] [Full Text] [Related]

  • 11. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
    [Abstract] [Full Text] [Related]

  • 12. Desipramine-induced Ca-independent apoptosis in Mg63 human osteosarcoma cells: dependence on P38 mitogen-activated protein kinase-regulated activation of caspase 3.
    Lu T, Huang CC, Lu YC, Lin KL, Liu SI, Wang BW, Chang PM, Chen IS, Chen SS, Tsai JY, Chou CT, Jan CR.
    Clin Exp Pharmacol Physiol; 2009 Mar 01; 36(3):297-303. PubMed ID: 18986328
    [Abstract] [Full Text] [Related]

  • 13. RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion.
    Calleros L, Lasa M, Rodríguez-Alvarez FJ, Toro MJ, Chiloeches A.
    Apoptosis; 2006 Jul 01; 11(7):1161-73. PubMed ID: 16699960
    [Abstract] [Full Text] [Related]

  • 14. Cocaine induces apoptosis in fetal rat myocardial cells through the p38 mitogen-activated protein kinase and mitochondrial/cytochrome c pathways.
    Li G, Xiao Y, Zhang L.
    J Pharmacol Exp Ther; 2005 Jan 01; 312(1):112-9. PubMed ID: 15365088
    [Abstract] [Full Text] [Related]

  • 15. Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation.
    Su JC, Lin KL, Chien CM, Lu CM, Chen YL, Chang LS, Lin SR.
    Life Sci; 2009 Sep 23; 85(13-14):505-16. PubMed ID: 19699753
    [Abstract] [Full Text] [Related]

  • 16. Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.
    Yu W, Liao QY, Hantash FM, Sanders BG, Kline K.
    Cancer Res; 2001 Sep 01; 61(17):6569-76. PubMed ID: 11522656
    [Abstract] [Full Text] [Related]

  • 17. Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner.
    Min J, Van Veldhoven PP, Zhang L, Hanigan MH, Alexander H, Alexander S.
    Mol Cancer Res; 2005 May 01; 3(5):287-96. PubMed ID: 15886300
    [Abstract] [Full Text] [Related]

  • 18. The effects of mitogen-activated protein kinase inhibitors or small interfering RNAs on gallic acid-induced HeLa cell death in relation to reactive oxygen species and glutathione.
    You BR, Park WH.
    J Agric Food Chem; 2011 Jan 26; 59(2):763-71. PubMed ID: 21166414
    [Abstract] [Full Text] [Related]

  • 19. p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis.
    Grethe S, Coltella N, Di Renzo MF, Pörn-Ares MI.
    Biochem Biophys Res Commun; 2006 Sep 01; 347(3):781-90. PubMed ID: 16843435
    [Abstract] [Full Text] [Related]

  • 20. Novel synthetic triterpenoid methyl 25-hydroxy-3-oxoolean-12-en-28-oate induces apoptosis through JNK and p38 MAPK pathways in human breast adenocarcinoma MCF-7 cells.
    Rabi T, Banerjee S.
    Mol Carcinog; 2008 Jun 01; 47(6):415-23. PubMed ID: 18058803
    [Abstract] [Full Text] [Related]

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