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Journal Abstract Search

278 related items for PubMed ID: 19578399

  • 1. Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.
    Kim J, Eltoum IE, Roh M, Wang J, Abdulkadir SA.
    PLoS Genet; 2009 Jul; 5(7):e1000542. PubMed ID: 19578399
    [Abstract] [Full Text] [Related]

  • 2. A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53.
    Kim J, Roh M, Doubinskaia I, Algarroba GN, Eltoum IE, Abdulkadir SA.
    Oncogene; 2012 Jan 19; 31(3):322-32. PubMed ID: 21685943
    [Abstract] [Full Text] [Related]

  • 3. Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer.
    Hubbard GK, Mutton LN, Khalili M, McMullin RP, Hicks JL, Bianchi-Frias D, Horn LA, Kulac I, Moubarek MS, Nelson PS, Yegnasubramanian S, De Marzo AM, Bieberich CJ.
    Cancer Res; 2016 Jan 15; 76(2):283-92. PubMed ID: 26554830
    [Abstract] [Full Text] [Related]

  • 4. Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis.
    Song H, Zhang B, Watson MA, Humphrey PA, Lim H, Milbrandt J.
    Oncogene; 2009 Sep 17; 28(37):3307-19. PubMed ID: 19597465
    [Abstract] [Full Text] [Related]

  • 5. Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways.
    Xing C, Ci X, Sun X, Fu X, Zhang Z, Dong EN, Hao ZZ, Dong JT.
    Neoplasia; 2014 Nov 17; 16(11):883-99. PubMed ID: 25425963
    [Abstract] [Full Text] [Related]

  • 6. Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.
    Berger PL, Frank SB, Schulz VV, Nollet EA, Edick MJ, Holly B, Chang TT, Hostetter G, Kim S, Miranti CK.
    Cancer Res; 2014 Jun 15; 74(12):3357-68. PubMed ID: 24762396
    [Abstract] [Full Text] [Related]

  • 7. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
    Manda KR, Tripathi P, Hsi AC, Ning J, Ruzinova MB, Liapis H, Bailey M, Zhang H, Maher CA, Humphrey PA, Andriole GL, Ding L, You Z, Chen F.
    Oncogene; 2016 Jun 23; 35(25):3282-92. PubMed ID: 26477312
    [Abstract] [Full Text] [Related]

  • 8. RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis.
    Bai Y, Yang Y, Yan Y, Zhong J, Blee AM, Pan Y, Ma T, Karnes RJ, Jimenez R, Xu W, Huang H.
    Theranostics; 2019 Jun 23; 9(12):3459-3475. PubMed ID: 31281490
    [Abstract] [Full Text] [Related]

  • 9. RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.
    Cho H, Herzka T, Zheng W, Qi J, Wilkinson JE, Bradner JE, Robinson BD, Castillo-Martin M, Cordon-Cardo C, Trotman LC.
    Cancer Discov; 2014 Mar 23; 4(3):318-33. PubMed ID: 24444712
    [Abstract] [Full Text] [Related]

  • 10. Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.
    Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He Y, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo ML, Sun Z.
    J Biol Chem; 2018 Dec 28; 293(52):20123-20136. PubMed ID: 30401749
    [Abstract] [Full Text] [Related]

  • 11. Caveolin-1 upregulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer.
    Yang G, Goltsov AA, Ren C, Kurosaka S, Edamura K, Logothetis R, DeMayo FJ, Troncoso P, Blando J, DiGiovanni J, Thompson TC.
    Mol Cancer Res; 2012 Feb 28; 10(2):218-29. PubMed ID: 22144662
    [Abstract] [Full Text] [Related]

  • 12. A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy.
    Huang X, Zhang Y, Tang Y, Butler N, Kim J, Guessous F, Schiff D, Mandell J, Abounader R.
    Neoplasia; 2013 Aug 28; 15(8):952-65. PubMed ID: 23908595
    [Abstract] [Full Text] [Related]

  • 13. MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells.
    Iwata T, Schultz D, Hicks J, Hubbard GK, Mutton LN, Lotan TL, Bethel C, Lotz MT, Yegnasubramanian S, Nelson WG, Dang CV, Xu M, Anele U, Koh CM, Bieberich CJ, De Marzo AM.
    PLoS One; 2010 Feb 25; 5(2):e9427. PubMed ID: 20195545
    [Abstract] [Full Text] [Related]

  • 14. Characterization of novel cell lines derived from a MYC-driven murine model of lethal metastatic adenocarcinoma of the prostate.
    Markowski MC, Hubbard GK, Hicks JL, Zheng Q, King A, Esopi D, Rege A, Yegnasubramanian S, Bieberich CJ, De Marzo AM.
    Prostate; 2018 Sep 25; 78(13):992-1000. PubMed ID: 29851094
    [Abstract] [Full Text] [Related]

  • 15. Additive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic Tumorigenesis.
    Sun X, Xing C, Fu X, Li J, Zhang B, Frierson HF, Dong JT.
    J Genet Genomics; 2015 Jul 20; 42(7):373-82. PubMed ID: 26233892
    [Abstract] [Full Text] [Related]

  • 16. Assessment of MYC/PTEN Status by Gene-Protein Assay in Grade Group 2 Prostate Biopsies.
    Salles DC, Vidotto T, Faisal FA, Tosoian JJ, Guedes LB, Muranyi A, Bai I, Singh S, Yan D, Shanmugam K, Lotan TL.
    J Mol Diagn; 2021 Aug 20; 23(8):1030-1041. PubMed ID: 34062284
    [Abstract] [Full Text] [Related]

  • 17. Irs2 inactivation suppresses tumor progression in Pten+/- mice.
    Szabolcs M, Keniry M, Simpson L, Reid LJ, Koujak S, Schiff SC, Davidian G, Licata S, Gruvberger-Saal S, Murty VV, Nandula S, Efstratiadis A, Kushner JA, White MF, Parsons R.
    Am J Pathol; 2009 Jan 20; 174(1):276-86. PubMed ID: 19095950
    [Abstract] [Full Text] [Related]

  • 18. The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision.
    Luchman HA, Benediktsson H, Villemaire ML, Peterson AC, Jirik FR.
    PLoS One; 2008 Jan 20; 3(12):e3940. PubMed ID: 19081794
    [Abstract] [Full Text] [Related]

  • 19. Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
    Anderson PD, McKissic SA, Logan M, Roh M, Franco OE, Wang J, Doubinskaia I, van der Meer R, Hayward SW, Eischen CM, Eltoum IE, Abdulkadir SA.
    J Clin Invest; 2012 May 20; 122(5):1907-19. PubMed ID: 22484818
    [Abstract] [Full Text] [Related]

  • 20. Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
    Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP.
    Sci Signal; 2009 Aug 18; 2(84):ra44. PubMed ID: 19690330
    [Abstract] [Full Text] [Related]

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