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Journal Abstract Search
131 related items for PubMed ID: 19581066
1. Production of a reactive metabolite of troglitazone by electrochemical oxidation performed in nonaqueous medium. Tahara K, Nishikawa T, Hattori Y, Iijima S, Kouno Y, Abe Y. J Pharm Biomed Anal; 2009 Dec 05; 50(5):1030-6. PubMed ID: 19581066 [Abstract] [Full Text] [Related]
4. Incorporation of an oxygen from water into troglitazone quinone by cytochrome P450 and myeloperoxidase. He K, Talaat RE, Woolf TF. Drug Metab Dispos; 2004 Apr 05; 32(4):442-6. PubMed ID: 15039298 [Abstract] [Full Text] [Related]
6. Metabolic activation of troglitazone: identification of a reactive metabolite and mechanisms involved. He K, Talaat RE, Pool WF, Reily MD, Reed JE, Bridges AJ, Woolf TF. Drug Metab Dispos; 2004 Jun 05; 32(6):639-46. PubMed ID: 15155556 [Abstract] [Full Text] [Related]
9. Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission. Kassahun K, Pearson PG, Tang W, McIntosh I, Leung K, Elmore C, Dean D, Wang R, Doss G, Baillie TA. Chem Res Toxicol; 2001 Jan 05; 14(1):62-70. PubMed ID: 11170509 [Abstract] [Full Text] [Related]
10. In vitro metabolism of ethoxidine by human CYP1A1 and rat microsomes: identification of metabolites by high-performance liquid chromatography combined with electrospray tandem mass spectrometry and accurate mass measurements by time-of-flight mass spectrometry. Deroussent A, Ré M, Hoellinger H, Vanquelef E, Duval O, Sonnier M, Cresteil T. Rapid Commun Mass Spectrom; 2004 Jan 05; 18(4):474-82. PubMed ID: 14966856 [Abstract] [Full Text] [Related]
12. 2,7-Disubstituted-pyrrolotriazine kinase inhibitors with an unusually high degree of reactive metabolite formation. Wells-Knecht KJ, Ott GR, Cheng M, Wells GJ, Breslin HJ, Gingrich DE, Weinberg L, Mesaros EF, Huang Z, Yazdanian M, Ator MA, Aimone LD, Zeigler K, Dorsey BD. Chem Res Toxicol; 2011 Nov 21; 24(11):1994-2003. PubMed ID: 22023349 [Abstract] [Full Text] [Related]
13. Investigation of the electrochemical oxidation products of zotepine and their fragmentation using on-line electrochemistry/electrospray ionization mass spectrometry. Nozaki K, Kitagawa H, Kimura S, Kagayama A, Arakawa R. J Mass Spectrom; 2006 May 21; 41(5):606-12. PubMed ID: 16575780 [Abstract] [Full Text] [Related]
14. Application of on-line electrochemical derivatization coupled with high-performance liquid chromatography electrospray ionization mass spectrometry for detection and quantitation of (p-chlorophenyl)aniline in biological samples. Chen H, Zhang Y, Mutlib AE, Zhong M. Anal Chem; 2006 Apr 01; 78(7):2413-21. PubMed ID: 16579628 [Abstract] [Full Text] [Related]
15. Involvement of different human glutathione transferase isoforms in the glutathione conjugation of reactive metabolites of troglitazone. Okada R, Maeda K, Nishiyama T, Aoyama S, Tozuka Z, Hiratsuka A, Ikeda T, Kusuhara H, Sugiyama Y. Drug Metab Dispos; 2011 Dec 01; 39(12):2290-7. PubMed ID: 21914835 [Abstract] [Full Text] [Related]
16. Metabolism of the A(1)1 adenosine receptor positron emission tomography ligand [18F]8-cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine ([18F]CPFPX) in rodents and humans. Bier D, Holschbach MH, Wutz W, Olsson RA, Coenen HH. Drug Metab Dispos; 2006 Apr 01; 34(4):570-6. PubMed ID: 16415116 [Abstract] [Full Text] [Related]
17. Application of CYP102A1M11H as a tool for the generation of protein adducts of reactive drug metabolites. Boerma JS, Vermeulen NP, Commandeur JN. Chem Res Toxicol; 2011 Aug 15; 24(8):1263-74. PubMed ID: 21639118 [Abstract] [Full Text] [Related]
18. Electrochemical generation of electrophilic drug metabolites: characterization of amodiaquine quinoneimine and cysteinyl conjugates by MS, IR, and NMR. Jurva U, Holmén A, Grönberg G, Masimirembwa C, Weidolf L. Chem Res Toxicol; 2008 Apr 15; 21(4):928-35. PubMed ID: 18361508 [Abstract] [Full Text] [Related]