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Journal Abstract Search

1351 related items for PubMed ID: 19601719

  • 1. Physiologically based pharmacokinetics (PBPK).
    Espié P, Tytgat D, Sargentini-Maier ML, Poggesi I, Watelet JB.
    Drug Metab Rev; 2009; 41(3):391-407. PubMed ID: 19601719
    [Abstract] [Full Text] [Related]

  • 2. Physiologically based pharmacokinetic (PBPK) modeling and simulation: applications in lead optimization.
    Peters SA, Ungell AL, Dolgos H.
    Curr Opin Drug Discov Devel; 2009 Jul; 12(4):509-18. PubMed ID: 19562647
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  • 5. Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.
    Lüpfert C, Reichel A.
    Chem Biodivers; 2005 Nov; 2(11):1462-86. PubMed ID: 17191947
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  • 6. Predicting human pharmacokinetics from preclinical data.
    Poggesi I.
    Curr Opin Drug Discov Devel; 2004 Jan; 7(1):100-11. PubMed ID: 14982153
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  • 7. PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach.
    Poulin P, Jones RD, Jones HM, Gibson CR, Rowland M, Chien JY, Ring BJ, Adkison KK, Ku MS, He H, Vuppugalla R, Marathe P, Fischer V, Dutta S, Sinha VK, Björnsson T, Lavé T, Yates JW.
    J Pharm Sci; 2011 Oct; 100(10):4127-57. PubMed ID: 21541937
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  • 8. Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.
    Fagerholm U.
    J Pharm Pharmacol; 2007 Jun; 59(6):803-28. PubMed ID: 17637173
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  • 9. Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.
    Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS.
    Drug Metab Dispos; 2012 May; 40(5):1007-17. PubMed ID: 22344703
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  • 10. In vitro measurements of metabolism for application in pharmacokinetic modeling.
    Lipscomb JC, Poet TS.
    Pharmacol Ther; 2008 Apr; 118(1):82-103. PubMed ID: 18374419
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  • 11. Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.
    Hosea NA, Collard WT, Cole S, Maurer TS, Fang RX, Jones H, Kakar SM, Nakai Y, Smith BJ, Webster R, Beaumont K.
    J Clin Pharmacol; 2009 May; 49(5):513-33. PubMed ID: 19299532
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  • 12. Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review.
    Zhao P, Zhang L, Grillo JA, Liu Q, Bullock JM, Moon YJ, Song P, Brar SS, Madabushi R, Wu TC, Booth BP, Rahman NA, Reynolds KS, Gil Berglund E, Lesko LJ, Huang SM.
    Clin Pharmacol Ther; 2011 Feb; 89(2):259-67. PubMed ID: 21191381
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  • 14. Integration of dissolution into physiologically-based pharmacokinetic models III: PK-Sim®.
    Willmann S, Thelen K, Lippert J.
    J Pharm Pharmacol; 2012 Jul; 64(7):997-1007. PubMed ID: 22686345
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  • 15. Application of PBPK modelling in drug discovery and development at Pfizer.
    Jones HM, Dickins M, Youdim K, Gosset JR, Attkins NJ, Hay TL, Gurrell IK, Logan YR, Bungay PJ, Jones BC, Gardner IB.
    Xenobiotica; 2012 Jan; 42(1):94-106. PubMed ID: 22035569
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  • 16. PBPK models for the prediction of in vivo performance of oral dosage forms.
    Kostewicz ES, Aarons L, Bergstrand M, Bolger MB, Galetin A, Hatley O, Jamei M, Lloyd R, Pepin X, Rostami-Hodjegan A, Sjögren E, Tannergren C, Turner DB, Wagner C, Weitschies W, Dressman J.
    Eur J Pharm Sci; 2014 Jun 16; 57():300-21. PubMed ID: 24060672
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  • 17. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: prediction of plasma concentration-time profiles in human from in vivo preclinical data by using the Wajima approach.
    Vuppugalla R, Marathe P, He H, Jones RD, Yates JW, Jones HM, Gibson CR, Chien JY, Ring BJ, Adkison KK, Ku MS, Fischer V, Dutta S, Sinha VK, Björnsson T, Lavé T, Poulin P.
    J Pharm Sci; 2011 Oct 16; 100(10):4111-26. PubMed ID: 21480234
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  • 18. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.
    Chen Y, Jin JY, Mukadam S, Malhi V, Kenny JR.
    Biopharm Drug Dispos; 2012 Mar 16; 33(2):85-98. PubMed ID: 22228214
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  • 19. Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation.
    De Buck SS, Mackie CE.
    Expert Opin Drug Metab Toxicol; 2007 Dec 16; 3(6):865-78. PubMed ID: 18028030
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