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Journal Abstract Search

694 related items for PubMed ID: 19604478

  • 1. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
    Chowdhury R, McDonough MA, Mecinović J, Loenarz C, Flashman E, Hewitson KS, Domene C, Schofield CJ.
    Structure; 2009 Jul 15; 17(7):981-9. PubMed ID: 19604478
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  • 5. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
    Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ.
    Science; 2001 Apr 20; 292(5516):468-72. PubMed ID: 11292861
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  • 6. Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
    Salnikow K, Donald SP, Bruick RK, Zhitkovich A, Phang JM, Kasprzak KS.
    J Biol Chem; 2004 Sep 24; 279(39):40337-44. PubMed ID: 15271983
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  • 8. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
    Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL.
    Mol Cell; 2005 Feb 18; 17(4):503-12. PubMed ID: 15721254
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  • 9. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
    Hewitson KS, Schofield CJ, Ratcliffe PJ.
    Methods Enzymol; 2007 Feb 18; 435():25-42. PubMed ID: 17998047
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  • 10. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P, Hirsilä M, Günzler V, Kivirikko KI, Myllyharju J.
    J Biol Chem; 2004 Mar 12; 279(11):9899-904. PubMed ID: 14701857
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  • 17. Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.
    Flashman E, Bagg EA, Chowdhury R, Mecinović J, Loenarz C, McDonough MA, Hewitson KS, Schofield CJ.
    J Biol Chem; 2008 Feb 15; 283(7):3808-15. PubMed ID: 18063574
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  • 19. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T, Zheng X, Ruas JL, Tanimoto K, Poellinger L.
    J Biol Chem; 2003 Feb 28; 278(9):6816-23. PubMed ID: 12468553
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  • 20. Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2.
    Figg WD, Fiorini G, Chowdhury R, Nakashima Y, Tumber A, McDonough MA, Schofield CJ.
    Proteins; 2023 Nov 28; 91(11):1510-1524. PubMed ID: 37449559
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