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Journal Abstract Search


243 related items for PubMed ID: 19609360

  • 1. The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits.
    Williamson SM, Robertson AP, Brown L, Williams T, Woods DJ, Martin RJ, Sattelle DB, Wolstenholme AJ.
    PLoS Pathog; 2009 Jul; 5(7):e1000517. PubMed ID: 19609360
    [Abstract] [Full Text] [Related]

  • 2. Expression of nicotinic acetylcholine receptor subunits from parasitic nematodes in Caenorhabditis elegans.
    Sloan MA, Reaves BJ, Maclean MJ, Storey BE, Wolstenholme AJ.
    Mol Biochem Parasitol; 2015 Nov; 204(1):44-50. PubMed ID: 26747395
    [Abstract] [Full Text] [Related]

  • 3. Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues.
    Abongwa M, Buxton SK, Courtot E, Charvet CL, Neveu C, McCoy CJ, Verma S, Robertson AP, Martin RJ.
    Br J Pharmacol; 2016 Aug; 173(16):2463-77. PubMed ID: 27238203
    [Abstract] [Full Text] [Related]

  • 4. Nicotinic acetylcholine receptors: a comparison of the nAChRs of Caenorhabditis elegans and parasitic nematodes.
    Holden-Dye L, Joyner M, O'Connor V, Walker RJ.
    Parasitol Int; 2013 Dec; 62(6):606-15. PubMed ID: 23500392
    [Abstract] [Full Text] [Related]

  • 5. Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species.
    Blanchard A, Guégnard F, Charvet CL, Crisford A, Courtot E, Sauvé C, Harmache A, Duguet T, O'Connor V, Castagnone-Sereno P, Reaves B, Wolstenholme AJ, Beech RN, Holden-Dye L, Neveu C.
    PLoS Pathog; 2018 May; 14(5):e1006996. PubMed ID: 29719008
    [Abstract] [Full Text] [Related]

  • 6. Cholinergic receptors on intestine cells of Ascaris suum and activation of nAChRs by levamisole.
    McHugh M, Williams P, Verma S, Powell-Coffman JA, Robertson AP, Martin RJ.
    Int J Parasitol Drugs Drug Resist; 2020 Aug; 13():38-50. PubMed ID: 32470835
    [Abstract] [Full Text] [Related]

  • 7. EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor.
    Choudhary S, Buxton SK, Puttachary S, Verma S, Mair GR, McCoy CJ, Reaves BJ, Wolstenholme AJ, Martin RJ, Robertson AP.
    PLoS Pathog; 2020 Apr; 16(4):e1008396. PubMed ID: 32243475
    [Abstract] [Full Text] [Related]

  • 8. Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum.
    Abongwa M, Marjanovic DS, Tipton JG, Zheng F, Martin RJ, Trailovic SM, Robertson AP.
    Int J Parasitol Drugs Drug Resist; 2018 Apr; 8(1):36-42. PubMed ID: 29366967
    [Abstract] [Full Text] [Related]

  • 9. Potential modulating effect of the Ascaris suum nicotinic acetylcholine receptor (nAChR) by compounds GSK575594A, diazepam and flumazenil discovered by structure-based virtual screening approach.
    Stevanovic S, Marjanović DS, Trailović SM, Zdravković N, Perdih A, Nikolic K.
    Mol Biochem Parasitol; 2021 Mar; 242():111350. PubMed ID: 33422580
    [Abstract] [Full Text] [Related]

  • 10. (S)-5-ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor.
    Zheng F, Du X, Chou TH, Robertson AP, Yu EW, VanVeller B, Martin RJ.
    Int J Parasitol Drugs Drug Resist; 2017 Apr; 7(1):12-22. PubMed ID: 28033523
    [Abstract] [Full Text] [Related]

  • 11. Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine- and derquantel-sensitive nAChRs.
    Buxton SK, Charvet CL, Neveu C, Cabaret J, Cortet J, Peineau N, Abongwa M, Courtot E, Robertson AP, Martin RJ.
    PLoS Pathog; 2014 Jan; 10(1):e1003870. PubMed ID: 24497826
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological characterization of a homomeric nicotinic acetylcholine receptor formed by Ancylostoma caninum ACR-16.
    Choudhary S, Tipton JG, Abongwa M, Brewer MT, Chelladurai JJ, Musselman N, Martin RJ, Robertson AP.
    Invert Neurosci; 2019 Sep 05; 19(4):11. PubMed ID: 31486912
    [Abstract] [Full Text] [Related]

  • 13. The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms.
    Hansen TVA, Cirera S, Neveu C, Courtot E, Charvet CL, Calloe K, Klaerke DA, Martin RJ.
    PLoS Pathog; 2021 Feb 05; 17(2):e1008982. PubMed ID: 33544769
    [Abstract] [Full Text] [Related]

  • 14. Heterologous formation of neonicotinoid-sensitive nAChRs containing UNC-38 and UNC-29 subunits from Bursaphelenchus xylophilus.
    Yu N, Liu Y, Wang X, Li J, Bao H, Liu Z.
    Pestic Biochem Physiol; 2017 Nov 05; 143():168-172. PubMed ID: 29183588
    [Abstract] [Full Text] [Related]

  • 15. Functional reconstitution of Haemonchus contortus acetylcholine receptors in Xenopus oocytes provides mechanistic insights into levamisole resistance.
    Boulin T, Fauvin A, Charvet CL, Cortet J, Cabaret J, Bessereau JL, Neveu C.
    Br J Pharmacol; 2011 Nov 05; 164(5):1421-32. PubMed ID: 21486278
    [Abstract] [Full Text] [Related]

  • 16. Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: a new lead for levamisole-resistance.
    Martin RJ, Bai G, Clark CL, Robertson AP.
    Br J Pharmacol; 2003 Nov 05; 140(6):1068-76. PubMed ID: 14581174
    [Abstract] [Full Text] [Related]

  • 17. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris.
    Martin RJ, Clark CL, Trailovic SM, Robertson AP.
    Int J Parasitol; 2004 Aug 05; 34(9):1083-90. PubMed ID: 15313135
    [Abstract] [Full Text] [Related]

  • 18. Nicotinic acetylcholine receptors in the nematode Caenorhabditis elegans.
    Ballivet M, Alliod C, Bertrand S, Bertrand D.
    J Mol Biol; 1996 May 03; 258(2):261-9. PubMed ID: 8627624
    [Abstract] [Full Text] [Related]

  • 19. Lophotoxin-insensitive nematode nicotinic acetylcholine receptors.
    Tornøe C, Holden-Dye L, Garland C, Abramson SN, Fleming JT, Sattelle DB.
    J Exp Biol; 1996 Oct 03; 199(Pt 10):2161-8. PubMed ID: 8896363
    [Abstract] [Full Text] [Related]

  • 20. The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening.
    Zheng F, Robertson AP, Abongwa M, Yu EW, Martin RJ.
    Int J Parasitol Drugs Drug Resist; 2016 Apr 03; 6(1):60-73. PubMed ID: 27054065
    [Abstract] [Full Text] [Related]


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