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Journal Abstract Search
212 related items for PubMed ID: 19620004
1. Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction. Williams DH, Adam F, Fenwick DR, Fok-Seang J, Gardner I, Hay D, Jaiessh R, Middleton DS, Mowbray CE, Parkinson T, Perros M, Pickford C, Platts M, Randall A, Siddle D, Stephenson PT, Tran TD, Vuong H. Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5246-9. PubMed ID: 19620004 [Abstract] [Full Text] [Related]
2. Design and optimisation of potent gp120-CD4 inhibitors. Tran TD, Adam FM, Calo F, Fenwick DR, Fok-Seang J, Gardner I, Hay DA, Perros M, Rawal J, Middleton DS, Parkinson T, Pickford C, Platts M, Randall A, Stephenson PT, Vuong H, Williams DH. Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5250-5. PubMed ID: 19632839 [Abstract] [Full Text] [Related]
3. Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity. Meanwell NA, Wallace OB, Wang H, Deshpande M, Pearce BC, Trehan A, Yeung KS, Qiu Z, Wright JJ, Robinson BA, Gong YF, Wang HG, Spicer TP, Blair WS, Shi PY, Lin PF. Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5136-9. PubMed ID: 19632112 [Abstract] [Full Text] [Related]
4. Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives. Wang T, Kadow JF, Zhang Z, Yin Z, Gao Q, Wu D, Parker DD, Yang Z, Zadjura L, Robinson BA, Gong YF, Spicer TP, Blair WS, Shi PY, Yamanaka G, Lin PF, Meanwell NA. Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5140-5. PubMed ID: 19664921 [Abstract] [Full Text] [Related]
5. Design, synthesis and evaluation of potential inhibitors of HIV gp120-CD4 interactions. Boussard C, Klimkait T, Mahmood N, Pritchard M, Gilbert IH. Bioorg Med Chem Lett; 2004 May 17; 14(10):2673-6. PubMed ID: 15109676 [Abstract] [Full Text] [Related]
6. CD4 mimics targeting the mechanism of HIV entry. Yamada Y, Ochiai C, Yoshimura K, Tanaka T, Ohashi N, Narumi T, Nomura W, Harada S, Matsushita S, Tamamura H. Bioorg Med Chem Lett; 2010 Jan 01; 20(1):354-8. PubMed ID: 19926478 [Abstract] [Full Text] [Related]
7. CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Narumi T, Ochiai C, Yoshimura K, Harada S, Tanaka T, Nomura W, Arai H, Ozaki T, Ohashi N, Matsushita S, Tamamura H. Bioorg Med Chem Lett; 2010 Oct 01; 20(19):5853-8. PubMed ID: 20728351 [Abstract] [Full Text] [Related]
8. Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. Wang T, Zhang Z, Wallace OB, Deshpande M, Fang H, Yang Z, Zadjura LM, Tweedie DL, Huang S, Zhao F, Ranadive S, Robinson BS, Gong YF, Ricarrdi K, Spicer TP, Deminie C, Rose R, Wang HG, Blair WS, Shi PY, Lin PF, Colonno RJ, Meanwell NA. J Med Chem; 2003 Sep 25; 46(20):4236-9. PubMed ID: 13678401 [Abstract] [Full Text] [Related]
9. Docking and 3D-QSAR studies of BMS-806 analogs as HIV-1 gp120 entry inhibitors. Teixeira C, Serradji N, Maurel F, Barbault F. Eur J Med Chem; 2009 Sep 25; 44(9):3524-32. PubMed ID: 19410340 [Abstract] [Full Text] [Related]
10. Preclinical pharmacokinetics of a novel HIV-1 attachment inhibitor BMS-378806 and prediction of its human pharmacokinetics. Yang Z, Zadjura L, D'Arienzo C, Marino A, Santone K, Klunk L, Greene D, Lin PF, Colonno R, Wang T, Meanwell N, Hansel S. Biopharm Drug Dispos; 2005 Dec 25; 26(9):387-402. PubMed ID: 16142720 [Abstract] [Full Text] [Related]
11. Small-molecule HIV-1 gp120 inhibitors to prevent HIV-1 entry: an emerging opportunity for drug development. Kadow J, Wang HG, Lin PF. Curr Opin Investig Drugs; 2006 Aug 25; 7(8):721-6. PubMed ID: 16955683 [Abstract] [Full Text] [Related]
12. Molecular docking guided structure based design of symmetrical N,N'-disubstituted urea/thiourea as HIV-1 gp120-CD4 binding inhibitors. Sivan SK, Vangala R, Manga V. Bioorg Med Chem; 2013 Aug 01; 21(15):4591-9. PubMed ID: 23777826 [Abstract] [Full Text] [Related]
13. CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents. Narumi T, Arai H, Yoshimura K, Harada S, Hirota Y, Ohashi N, Hashimoto C, Nomura W, Matsushita S, Tamamura H. Bioorg Med Chem; 2013 May 01; 21(9):2518-26. PubMed ID: 23535561 [Abstract] [Full Text] [Related]
14. Small molecular CD4 mimics as HIV entry inhibitors. Narumi T, Arai H, Yoshimura K, Harada S, Nomura W, Matsushita S, Tamamura H. Bioorg Med Chem; 2011 Nov 15; 19(22):6735-42. PubMed ID: 22014753 [Abstract] [Full Text] [Related]