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Journal Abstract Search


193 related items for PubMed ID: 19632257

  • 1. Mass spectrometry identifies multiple organophosphorylated sites on tubulin.
    Grigoryan H, Schopfer LM, Peeples ES, Duysen EG, Grigoryan M, Thompson CM, Lockridge O.
    Toxicol Appl Pharmacol; 2009 Oct 15; 240(2):149-58. PubMed ID: 19632257
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  • 2. Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: implications for neurotoxicity.
    Grigoryan H, Lockridge O.
    Toxicol Appl Pharmacol; 2009 Oct 15; 240(2):143-8. PubMed ID: 19631231
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  • 3. Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.
    Jiang W, Duysen EG, Hansen H, Shlyakhtenko L, Schopfer LM, Lockridge O.
    Toxicol Sci; 2010 May 15; 115(1):183-93. PubMed ID: 20142434
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  • 4. Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.
    Grigoryan H, Schopfer LM, Thompson CM, Terry AV, Masson P, Lockridge O.
    Chem Biol Interact; 2008 Sep 25; 175(1-3):180-6. PubMed ID: 18502412
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  • 5. Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity.
    Schopfer LM, Lockridge O.
    J Biol Chem; 2018 Aug 31; 293(35):13566-13577. PubMed ID: 30006344
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  • 6. Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry.
    Jiang W, Duysen EG, Lockridge O.
    Toxicology; 2012 May 16; 295(1-3):15-22. PubMed ID: 22406659
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  • 10. Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.
    Schopfer LM, Grigoryan H, Li B, Nachon F, Masson P, Lockridge O.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May 15; 878(17-18):1297-311. PubMed ID: 19762289
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  • 11. Chlorpyrifos Oxon-Induced Isopeptide Bond Formation in Human Butyrylcholinesterase.
    Biberoglu K, Tacal O, Schopfer LM, Lockridge O.
    Molecules; 2020 Jan 25; 25(3):. PubMed ID: 31991818
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  • 12. Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine.
    Grigoryan H, Li B, Anderson EK, Xue W, Nachon F, Lockridge O, Schopfer LM.
    Chem Biol Interact; 2009 Aug 14; 180(3):492-8. PubMed ID: 19539807
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  • 15. Mass Spectrometry Identifies Isopeptide Cross-Links Promoted by Diethylphosphorylated Lysine in Proteins Treated with Chlorpyrifos Oxon.
    Schopfer LM, Lockridge O.
    Chem Res Toxicol; 2019 Apr 15; 32(4):762-772. PubMed ID: 30844252
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  • 17. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411.
    Li B, Schopfer LM, Hinrichs SH, Masson P, Lockridge O.
    Anal Biochem; 2007 Feb 15; 361(2):263-72. PubMed ID: 17188226
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