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Journal Abstract Search

131 related items for PubMed ID: 19640718

  • 1. Amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines as CXCR4 antagonists with potent activity against HIV-1.
    Gudmundsson KS, Sebahar PR, Richardson LD, Miller JF, Turner EM, Catalano JG, Spaltenstein A, Lawrence W, Thomson M, Jenkinson S.
    Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5048-52. PubMed ID: 19640718
    [Abstract] [Full Text] [Related]

  • 2. Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents.
    Miller JF, Turner EM, Gudmundsson KS, Jenkinson S, Spaltenstein A, Thomson M, Wheelan P.
    Bioorg Med Chem Lett; 2010 Apr 01; 20(7):2125-8. PubMed ID: 20207537
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication.
    Skerlj R, Bridger G, McEachern E, Harwig C, Smith C, Wilson T, Veale D, Yee H, Crawford J, Skupinska K, Wauthy R, Yang W, Zhu Y, Bogucki D, Di Fluri M, Langille J, Huskens D, De Clercq E, Schols D.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):262-6. PubMed ID: 21109432
    [Abstract] [Full Text] [Related]

  • 4. Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication.
    Skerlj R, Bridger G, McEachern E, Harwig C, Smith C, Kaller A, Veale D, Yee H, Skupinska K, Wauthy R, Wang L, Baird I, Zhu Y, Burrage K, Yang W, Sartori M, Huskens D, De Clercq E, Schols D.
    Bioorg Med Chem Lett; 2011 Mar 01; 21(5):1414-8. PubMed ID: 21295470
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and in vitro anti-HIV activity of certain 2-(1H-benzimidazol-2-ylamino)pyrimidin-4(3H)-ones and related derivatives.
    Badawey el-S, Kappe T.
    Arch Pharm (Weinheim); 1997 Mar 01; 330(3):59-62. PubMed ID: 9167448
    [Abstract] [Full Text] [Related]

  • 6. Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1.
    Catalano JG, Gudmundsson KS, Svolto A, Boggs SD, Miller JF, Spaltenstein A, Thomson M, Wheelan P, Minick DJ, Phelps DP, Jenkinson S.
    Bioorg Med Chem Lett; 2010 Apr 01; 20(7):2186-90. PubMed ID: 20194023
    [Abstract] [Full Text] [Related]

  • 7. Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors.
    Monforte AM, Rao A, Logoteta P, Ferro S, De Luca L, Barreca ML, Iraci N, Maga G, De Clercq E, Pannecouque C, Chimirri A.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7429-35. PubMed ID: 18585918
    [Abstract] [Full Text] [Related]

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  • 9. Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity.
    Miller JF, Gudmundsson KS, D'Aurora Richardson L, Jenkinson S, Spaltenstein A, Thomson M, Wheelan P.
    Bioorg Med Chem Lett; 2010 May 15; 20(10):3026-30. PubMed ID: 20443225
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands.
    Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H.
    Bioorg Med Chem; 2019 Mar 15; 27(6):1130-1138. PubMed ID: 30772128
    [Abstract] [Full Text] [Related]

  • 11. Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication.
    Skerlj RT, Bridger GJ, Kaller A, McEachern EJ, Crawford JB, Zhou Y, Atsma B, Langille J, Nan S, Veale D, Wilson T, Harwig C, Hatse S, Princen K, De Clercq E, Schols D.
    J Med Chem; 2010 Apr 22; 53(8):3376-88. PubMed ID: 20297846
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and anti-hIV activity of 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole structurally-related 1,2-substituted benzimidazoles.
    Rao A, Chimirri A, De Clercq E, Monforte AM, Monforte P, Pannecouque C, Zappalà M.
    Farmaco; 2002 Oct 22; 57(10):819-23. PubMed ID: 12420877
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4.
    Bridger GJ, Skerlj RT, Padmanabhan S, Martellucci SA, Henson GW, Struyf S, Witvrouw M, Schols D, De Clercq E.
    J Med Chem; 1999 Sep 23; 42(19):3971-81. PubMed ID: 10508445
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.
    Roth T, Morningstar ML, Boyer PL, Hughes SH, Buckheit RW, Michejda CJ.
    J Med Chem; 1997 Dec 19; 40(26):4199-207. PubMed ID: 9435891
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication.
    Bridger GJ, Skerlj RT, Hernandez-Abad PE, Bogucki DE, Wang Z, Zhou Y, Nan S, Boehringer EM, Wilson T, Crawford J, Metz M, Hatse S, Princen K, De Clercq E, Schols D.
    J Med Chem; 2010 Feb 11; 53(3):1250-60. PubMed ID: 20043638
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  • 17. New macrocyclic amines showing activity as HIV entry inhibitors against wild type and multi-drug resistant viruses.
    Rusconi S, Lo Cicero M, Viganò O, Sirianni F, Bulgheroni E, Ferramosca S, Bencini A, Bianchi A, Ruiz L, Cabrera C, Martinez-Picado J, Supuran CT, Galli M.
    Molecules; 2009 May 22; 14(5):1927-37. PubMed ID: 19471212
    [Abstract] [Full Text] [Related]

  • 18. Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors.
    Puig de la Bellacasa R, Gibert A, Planesas JM, Ros-Blanco L, Batllori X, Badía R, Clotet B, Esté J, Teixidó J, Borrell JI.
    Org Biomol Chem; 2016 Jan 28; 14(4):1455-1472. PubMed ID: 26691389
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