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166 related items for PubMed ID: 19672878

  • 1. The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides.
    Ja WW, Carvalho GB, Madrigal M, Roberts RW, Benzer S.
    Protein Sci; 2009 Nov; 18(11):2203-8. PubMed ID: 19672878
    [Abstract] [Full Text] [Related]

  • 2. The predicted binding site and dynamics of peptide inhibitors to the Methuselah GPCR from Drosophila melanogaster.
    Heo J, Ja WW, Benzer S, Goddard WA.
    Biochemistry; 2008 Dec 02; 47(48):12740-9. PubMed ID: 18991399
    [Abstract] [Full Text] [Related]

  • 3. Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor.
    Ja WW, West AP, Delker SL, Bjorkman PJ, Benzer S, Roberts RW.
    Nat Chem Biol; 2007 Jul 02; 3(7):415-9. PubMed ID: 17546039
    [Abstract] [Full Text] [Related]

  • 4. The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila.
    Cvejic S, Zhu Z, Felice SJ, Berman Y, Huang XY.
    Nat Cell Biol; 2004 Jun 02; 6(6):540-6. PubMed ID: 15133470
    [Abstract] [Full Text] [Related]

  • 5. Modulation of methuselah expression targeted to Drosophila insulin-producing cells extends life and enhances oxidative stress resistance.
    Gimenez LE, Ghildyal P, Fischer KE, Hu H, Ja WW, Eaton BA, Wu Y, Austad SN, Ranjan R.
    Aging Cell; 2013 Feb 02; 12(1):121-9. PubMed ID: 23121290
    [Abstract] [Full Text] [Related]

  • 6. Efficacy of methuselah gene mutation toward tolerance of dichlorvos exposure in Drosophila melanogaster.
    Pandey A, Khatoon R, Saini S, Vimal D, Patel DK, Narayan G, Chowdhuri DK.
    Free Radic Biol Med; 2015 Jun 02; 83():54-65. PubMed ID: 25746179
    [Abstract] [Full Text] [Related]

  • 7. Myoinhibiting peptides are the ancestral ligands of the promiscuous Drosophila sex peptide receptor.
    Poels J, Van Loy T, Vandersmissen HP, Van Hiel B, Van Soest S, Nachman RJ, Vanden Broeck J.
    Cell Mol Life Sci; 2010 Oct 02; 67(20):3511-22. PubMed ID: 20458515
    [Abstract] [Full Text] [Related]

  • 8. Massive parallel expansions of Methuselah/Methuselah-like receptors in schizophoran Diptera.
    Friedrich M, Chahine H, Al-Jageta C, Badreddine H.
    J Exp Zool B Mol Dev Evol; 2018 Sep 02; 330(6-7):384-389. PubMed ID: 30058118
    [Abstract] [Full Text] [Related]

  • 9. Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan.
    West AP, Llamas LL, Snow PM, Benzer S, Bjorkman PJ.
    Proc Natl Acad Sci U S A; 2001 Mar 27; 98(7):3744-9. PubMed ID: 11274391
    [Abstract] [Full Text] [Related]

  • 10. Transcriptional regulation of the methuselah gene by dorsal protein in Drosophila melanogaster.
    Kim H, Kim J, Lee Y, Yang J, Han K.
    Mol Cells; 2006 Apr 30; 21(2):261-8. PubMed ID: 16682822
    [Abstract] [Full Text] [Related]

  • 11. Drosophila insulin release is triggered by adipose Stunted ligand to brain Methuselah receptor.
    Delanoue R, Meschi E, Agrawal N, Mauri A, Tsatskis Y, McNeill H, Léopold P.
    Science; 2016 Sep 30; 353(6307):1553-1556. PubMed ID: 27708106
    [Abstract] [Full Text] [Related]

  • 12. Complexity of the genetic basis of ageing in nature revealed by a clinal study of lifespan and methuselah, a gene for ageing, in Drosophila from eastern Australia.
    Sgrò CM, van Heerwaarden B, Kellermann V, Wee CW, Hoffmann AA, Lee SF.
    Mol Ecol; 2013 Jul 30; 22(13):3539-51. PubMed ID: 23802551
    [Abstract] [Full Text] [Related]

  • 13. Gene Ages, Nomenclatures, and Functional Diversification of the Methuselah/Methuselah-Like GPCR Family in Drosophila and Tribolium.
    Friedrich M, Jones JW.
    J Exp Zool B Mol Dev Evol; 2016 Dec 30; 326(8):453-463. PubMed ID: 28074535
    [Abstract] [Full Text] [Related]

  • 14. Methuselah/Methuselah-like G protein-coupled receptors constitute an ancient metazoan gene family.
    de Mendoza A, Jones JW, Friedrich M.
    Sci Rep; 2016 Feb 26; 6():21801. PubMed ID: 26915348
    [Abstract] [Full Text] [Related]

  • 15. Clines and adaptive evolution in the methuselah gene region in Drosophila melanogaster.
    Duvernell DD, Schmidt PS, Eanes WF.
    Mol Ecol; 2003 May 26; 12(5):1277-85. PubMed ID: 12694290
    [Abstract] [Full Text] [Related]

  • 16. Dramatic expansion and developmental expression diversification of the methuselah gene family during recent Drosophila evolution.
    Patel MV, Hallal DA, Jones JW, Bronner DN, Zein R, Caravas J, Husain Z, Friedrich M, Vanberkum MF.
    J Exp Zool B Mol Dev Evol; 2012 Jul 26; 318(5):368-87. PubMed ID: 22711569
    [Abstract] [Full Text] [Related]

  • 17. Identification of the endogenous cysteine-rich peptide trissin, a ligand for an orphan G protein-coupled receptor in Drosophila.
    Ida T, Takahashi T, Tominaga H, Sato T, Kume K, Yoshizawa-Kumagaye K, Nishio H, Kato J, Murakami N, Miyazato M, Kangawa K, Kojima M.
    Biochem Biophys Res Commun; 2011 Oct 14; 414(1):44-8. PubMed ID: 21939639
    [Abstract] [Full Text] [Related]

  • 18. Functional significance of allelic variation at methuselah, an aging gene in Drosophila.
    Paaby AB, Schmidt PS.
    PLoS One; 2008 Apr 16; 3(4):e1987. PubMed ID: 18414670
    [Abstract] [Full Text] [Related]

  • 19. The Drosophila melanogaster methuselah gene: a novel gene with ancient functions.
    Araújo AR, Reis M, Rocha H, Aguiar B, Morales-Hojas R, Macedo-Ribeiro S, Fonseca NA, Reboiro-Jato D, Reboiro-Jato M, Fdez-Riverola F, Vieira CP, Vieira J.
    PLoS One; 2013 Apr 16; 8(5):e63747. PubMed ID: 23696853
    [Abstract] [Full Text] [Related]

  • 20. Extended life-span and stress resistance in the Drosophila mutant methuselah.
    Lin YJ, Seroude L, Benzer S.
    Science; 1998 Oct 30; 282(5390):943-6. PubMed ID: 9794765
    [Abstract] [Full Text] [Related]

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