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Journal Abstract Search

280 related items for PubMed ID: 19674061

  • 1. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar; 51(3):323-32. PubMed ID: 19674061
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  • 2. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
    Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M.
    Neuropharmacology; 2010 Jun; 58(8):1228-36. PubMed ID: 20230843
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  • 3. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
    Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2008 Jul; 49(7):1202-12. PubMed ID: 18435754
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  • 4. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A, Noyori H, Yagen B, Shimshoni JA, Bialer M, Fujiwara M.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct; 86(5):394-401. PubMed ID: 19830722
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  • 7. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
    Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M.
    Epilepsia; 2014 Feb; 55(2):353-61. PubMed ID: 24313671
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  • 8. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Sobol E, Bialer M, Yagen B.
    J Med Chem; 2004 Aug 12; 47(17):4316-26. PubMed ID: 15294003
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  • 9. Preliminary evaluation of the anticonvulsant activity of a valproic acid analog: N-(2-propylpentanoyl) urea.
    Tantisira B, Tantisira MH, Patarapanich C, Sooksawate T, Chunngam T.
    Res Commun Mol Pathol Pharmacol; 1997 Aug 12; 97(2):151-64. PubMed ID: 9344228
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  • 10. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
    Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2007 Dec 13; 50(25):6419-27. PubMed ID: 17994680
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  • 13. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.
    Shekh-Ahmad T, Bialer M, Yavin E.
    Epilepsy Res; 2012 Feb 13; 98(2-3):238-46. PubMed ID: 22057163
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  • 14. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
    Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M.
    Epilepsy Res; 2007 Jan 13; 73(1):75-84. PubMed ID: 16997532
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  • 15. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
    Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M.
    Neuropharmacology; 2006 Sep 13; 51(4):933-46. PubMed ID: 16890251
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  • 17. Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives.
    Shimshoni JA, Bialer M, Yagen B.
    Bioorg Med Chem; 2008 Jun 01; 16(11):6297-305. PubMed ID: 18472270
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  • 18. Pharmacokinetic-pharmacodynamic relationships of (2S,3S)-valnoctamide and its stereoisomer (2R,3S)-valnoctamide in rodent models of epilepsy.
    Isoherranen N, White HS, Klein BD, Roeder M, Woodhead JH, Schurig V, Yagen B, Bialer M.
    Pharm Res; 2003 Aug 01; 20(8):1293-301. PubMed ID: 12948028
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  • 19. Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus.
    Hen N, Shekh-Ahmad T, Yagen B, McDonough JH, Finnell RH, Wlodarczyk B, Bialer M.
    J Med Chem; 2013 Aug 22; 56(16):6467-77. PubMed ID: 23879329
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  • 20. Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activity.
    Giardina WJ, Dart MJ, Harris RR, Bitner RS, Radek RJ, Fox GB, Chemburkar SR, Marsh KC, Waring JF, Hui JY, Chen J, Curzon P, Grayson GK, Komater VA, Ku Y, Lockwood M, Miner HM, Nikkel AL, Pan JB, Pu YM, Wang L, Bennani Y, Durmuller N, Jolly R, Roux S, Sullivan JP, Decker MW.
    Epilepsia; 2005 Sep 22; 46(9):1349-61. PubMed ID: 16146429
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