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Journal Abstract Search

143 related items for PubMed ID: 19679379

  • 1. Synthesis and preliminary pharmacological evaluation of imidazo[2,1-f]purine-2,4-dione derivatives.
    Zagórska A, Jurczyk S, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E.
    Eur J Med Chem; 2009 Nov; 44(11):4288-96. PubMed ID: 19679379
    [Abstract] [Full Text] [Related]

  • 2. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents.
    Zagórska A, Bucki A, Kołaczkowski M, Siwek A, Głuch-Lutwin M, Starowicz G, Kazek G, Partyka A, Wesołowska A, Słoczyńska K, Pękala E, Pawłowski M.
    J Enzyme Inhib Med Chem; 2016 May 06; 31(sup3):10-24. PubMed ID: 27353547
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationships and molecular studies of novel arylpiperazinylalkyl purine-2,4-diones and purine-2,4,8-triones with antidepressant and anxiolytic-like activity.
    Zagórska A, Kołaczkowski M, Bucki A, Siwek A, Kazek G, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pawłowski M.
    Eur J Med Chem; 2015 Jun 05; 97():142-54. PubMed ID: 25965777
    [Abstract] [Full Text] [Related]

  • 5. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E, Pawłowski M, Martinez J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):2907-19. PubMed ID: 17321139
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
    Czopek A, Byrtus H, Kołaczkowski M, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E.
    Eur J Med Chem; 2010 Apr 15; 45(4):1295-303. PubMed ID: 20060623
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-dione.
    Chloń G, Pawłowski M, Duszyńska B, Szaro A, Tatarczńska E, Kłodzińska AL, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2001 Apr 15; 53(4):359-68. PubMed ID: 11990082
    [Abstract] [Full Text] [Related]

  • 8. New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.
    Chłoń-Rzepa G, Zagórska A, Bucki A, Kołaczkowski M, Pawłowski M, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pękala E, Słoczyńska K.
    Arch Pharm (Weinheim); 2015 Apr 15; 348(4):242-53. PubMed ID: 25773907
    [Abstract] [Full Text] [Related]

  • 9. New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists.
    Baraldi PG, Preti D, Tabrizi MA, Fruttarolo F, Romagnoli R, Zaid NA, Moorman AR, Merighi S, Varani K, Borea PA.
    J Med Chem; 2005 Jul 14; 48(14):4697-701. PubMed ID: 16000006
    [Abstract] [Full Text] [Related]

  • 10. 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
    Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M.
    Bioorg Med Chem; 2007 Aug 01; 15(15):5239-50. PubMed ID: 17517514
    [Abstract] [Full Text] [Related]

  • 11. New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation.
    Chłoń-Rzepa G, Zmudzki P, Satała G, Duszyńska B, Partyka A, Wróbel D, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Pawłowski M, Zajdel P.
    Pharmacol Rep; 2013 Aug 01; 65(1):15-29. PubMed ID: 23563020
    [Abstract] [Full Text] [Related]

  • 12. Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists.
    Partyka A, Zagórska A, Kotańska M, Walczak M, Jastrzębska-Więsek M, Knutelska J, Bednarski M, Głuch-Lutwin M, Mordyl B, Janiszewska P, Wesołowska A.
    PLoS One; 2020 Aug 01; 15(8):e0237196. PubMed ID: 32764777
    [Abstract] [Full Text] [Related]

  • 13. Novel tricyclic[2,1-f]theophylline derivatives of LCAP with activity in mouse models of affective disorders.
    Partyka A, Jarosz J, Wasik A, Jastrzębska-Więsek M, Zagórska A, Pawłowski M, Wesołowska A.
    J Pharm Pharmacol; 2014 Dec 01; 66(12):1755-62. PubMed ID: 25131522
    [Abstract] [Full Text] [Related]

  • 14. Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.
    Partyka A, Chłoń-Rzepa G, Wasik A, Jastrzębska-Więsek M, Bucki A, Kołaczkowski M, Satała G, Bojarski AJ, Wesołowska A.
    Bioorg Med Chem; 2015 Jan 01; 23(1):212-21. PubMed ID: 25435254
    [Abstract] [Full Text] [Related]

  • 15. Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity.
    Paluchowska MH, Mokrosz MJ, Charakchieva-Minol S, Duszyńska B, Kozioł A, Wesołowska A, Stachowicz K, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2003 Jan 01; 55(4):543-52. PubMed ID: 14581712
    [Abstract] [Full Text] [Related]

  • 16. Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities.
    Zagórska A, Partyka A, Bucki A, Kołaczkowski M, Jastrzębska-Więsek M, Czopek A, Siwek A, Głuch-Lutwin M, Bednarski M, Bajda M, Jończyk J, Piska K, Koczurkiewicz P, Wesołowska A, Pawłowski M.
    Chem Biol Drug Des; 2019 Apr 01; 93(4):511-521. PubMed ID: 30422400
    [Abstract] [Full Text] [Related]

  • 17. Introduction of a new complex imide system into the structure of LCAPs. The synthesis and a 5-HT1A, 5-HT2A and D2 receptor binding study.
    Kossakowski J, Raszkiewicz A, Bugno R, Bojarski AJ.
    Pol J Pharmacol; 2004 Apr 01; 56(6):843-8. PubMed ID: 15662099
    [Abstract] [Full Text] [Related]

  • 18. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F, Perissutti E, Severino B, Santagada V, Cirillo D, Terracciano S, Massarelli P, Bruni G, Collavoli E, Renner C, Caliendo G.
    J Med Chem; 2005 Aug 25; 48(17):5495-503. PubMed ID: 16107148
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
    López-Rodríguez ML, Rosado ML, Benhamú B, Morcillo MJ, Sanz AM, Orensanz L, Beneitez ME, Fuentes JA, Manzanares J.
    J Med Chem; 1996 Oct 25; 39(22):4439-50. PubMed ID: 8893838
    [Abstract] [Full Text] [Related]

  • 20. The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
    Paluchowska MH, Bugno R, Duszyńska B, Tatarczyńska E, Nikiforuk A, Lenda T, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2007 Nov 15; 15(22):7116-25. PubMed ID: 17825569
    [Abstract] [Full Text] [Related]

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