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242 related items for PubMed ID: 19699819

  • 1. The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.
    Mitrofan LM, Pelkonen J, Mönkkönen J.
    Bone; 2009 Dec; 45(6):1153-60. PubMed ID: 19699819
    [Abstract] [Full Text] [Related]

  • 2. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.
    Räikkönen J, Mönkkönen H, Auriola S, Mönkkönen J.
    Biochem Pharmacol; 2010 Mar 01; 79(5):777-83. PubMed ID: 19819230
    [Abstract] [Full Text] [Related]

  • 3. Zoledronic acid-induced IPP/ApppI production in vivo.
    Mönkkönen H, Ottewell PD, Kuokkanen J, Mönkkönen J, Auriola S, Holen I.
    Life Sci; 2007 Sep 08; 81(13):1066-70. PubMed ID: 17850825
    [Abstract] [Full Text] [Related]

  • 4. Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry.
    Jauhiainen M, Mönkkönen H, Räikkönen J, Mönkkönen J, Auriola S.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Oct 01; 877(27):2967-75. PubMed ID: 19665949
    [Abstract] [Full Text] [Related]

  • 5. Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro.
    Räikkönen J, Crockett JC, Rogers MJ, Mönkkönen H, Auriola S, Mönkkönen J.
    Br J Pharmacol; 2009 Jun 01; 157(3):427-35. PubMed ID: 19371349
    [Abstract] [Full Text] [Related]

  • 6. High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo.
    Benzaïd I, Mönkkönen H, Stresing V, Bonnelye E, Green J, Mönkkönen J, Touraine JL, Clézardin P.
    Cancer Res; 2011 Jul 01; 71(13):4562-72. PubMed ID: 21646473
    [Abstract] [Full Text] [Related]

  • 7. Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells.
    Räikkönen J, Taskinen M, Dunford JE, Mönkkönen H, Auriola S, Mönkkönen J.
    Biochem Biophys Res Commun; 2011 Apr 22; 407(4):663-7. PubMed ID: 21420384
    [Abstract] [Full Text] [Related]

  • 8. Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells.
    Mitrofan LM, Castells FB, Pelkonen J, Mönkkönen J.
    J Biol Chem; 2010 Jan 15; 285(3):1967-79. PubMed ID: 19875454
    [Abstract] [Full Text] [Related]

  • 9. Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells.
    Goffinet M, Thoulouzan M, Pradines A, Lajoie-Mazenc I, Weinbaum C, Faye JC, Séronie-Vivien S.
    BMC Cancer; 2006 Mar 15; 6():60. PubMed ID: 16539721
    [Abstract] [Full Text] [Related]

  • 10. Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth.
    Mönkkönen H, Kuokkanen J, Holen I, Evans A, Lefley DV, Jauhiainen M, Auriola S, Mönkkönen J.
    Anticancer Drugs; 2008 Apr 15; 19(4):391-9. PubMed ID: 18454049
    [Abstract] [Full Text] [Related]

  • 11. Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells.
    Ebert R, Meissner-Weigl J, Zeck S, Määttä J, Auriola S, Coimbra de Sousa S, Mentrup B, Graser S, Rachner TD, Hofbauer LC, Jakob F.
    Mol Cancer; 2014 Dec 11; 13():265. PubMed ID: 25496233
    [Abstract] [Full Text] [Related]

  • 12. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel.
    Jagdev SP, Coleman RE, Shipman CM, Rostami-H A, Croucher PI.
    Br J Cancer; 2001 Apr 20; 84(8):1126-34. PubMed ID: 11308265
    [Abstract] [Full Text] [Related]

  • 13. In vivo phosphoantigen levels in bisphosphonate-treated human breast tumors trigger Vγ9Vδ2 T-cell antitumor cytotoxicity through ICAM-1 engagement.
    Benzaïd I, Mönkkönen H, Bonnelye E, Mönkkönen J, Clézardin P.
    Clin Cancer Res; 2012 Nov 15; 18(22):6249-59. PubMed ID: 23032740
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.
    Merrell MA, Wakchoure S, Lehenkari PP, Harris KW, Selander KS.
    Eur J Pharmacol; 2007 Sep 10; 570(1-3):27-37. PubMed ID: 17640631
    [Abstract] [Full Text] [Related]

  • 15. Zoledronate has an antitumor effect and induces actin rearrangement in dexamethasone-resistant myeloma cells.
    Koizumi M, Nakaseko C, Ohwada C, Takeuchi M, Ozawa S, Shimizu N, Cho R, Nishimura M, Saito Y.
    Eur J Haematol; 2007 Nov 10; 79(5):382-91. PubMed ID: 17903213
    [Abstract] [Full Text] [Related]

  • 16. Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells.
    Ebert R, Zeck S, Meissner-Weigl J, Klotz B, Rachner TD, Benad P, Klein-Hitpass L, Rudert M, Hofbauer LC, Jakob F.
    Bone; 2012 Mar 10; 50(3):723-32. PubMed ID: 22166808
    [Abstract] [Full Text] [Related]

  • 17. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells.
    Oades GM, Senaratne SG, Clarke IA, Kirby RS, Colston KW.
    J Urol; 2003 Jul 10; 170(1):246-52. PubMed ID: 12796698
    [Abstract] [Full Text] [Related]

  • 18. Nitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthase.
    Stresing V, Fournier PG, Bellahcène A, Benzaïd I, Mönkkönen H, Colombel M, Ebetino FH, Castronovo V, Clézardin P.
    Bone; 2011 Feb 10; 48(2):259-66. PubMed ID: 20920623
    [Abstract] [Full Text] [Related]

  • 19. Bisphosphonates: the first 40 years.
    Russell RG.
    Bone; 2011 Jul 10; 49(1):2-19. PubMed ID: 21555003
    [Abstract] [Full Text] [Related]

  • 20. Isopentenyl pyrophosphate secreted from Zoledronate-stimulated myeloma cells, activates the chemotaxis of γδT cells.
    Ashihara E, Munaka T, Kimura S, Nakagawa S, Nakagawa Y, Kanai M, Hirai H, Abe H, Miida T, Yamato S, Shoji S, Maekawa T.
    Biochem Biophys Res Commun; 2015 Aug 07; 463(4):650-5. PubMed ID: 26047704
    [Abstract] [Full Text] [Related]

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