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525 related items for PubMed ID: 19700418

  • 1. Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.
    Calleros L, Sánchez-Hernández I, Baquero P, Toro MJ, Chiloeches A.
    Carcinogenesis; 2009 Oct; 30(10):1670-7. PubMed ID: 19700418
    [Abstract] [Full Text] [Related]

  • 2. RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion.
    Calleros L, Lasa M, Rodríguez-Alvarez FJ, Toro MJ, Chiloeches A.
    Apoptosis; 2006 Jul; 11(7):1161-73. PubMed ID: 16699960
    [Abstract] [Full Text] [Related]

  • 3. Human melanoma cells expressing V600E B-RAF are susceptible to IGF1R targeting by small interfering RNAs.
    Yeh AH, Bohula EA, Macaulay VM.
    Oncogene; 2006 Oct 26; 25(50):6574-81. PubMed ID: 16715137
    [Abstract] [Full Text] [Related]

  • 4. Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells.
    Cheng G, Meinkoth JL.
    Oncogene; 2001 Nov 01; 20(50):7334-41. PubMed ID: 11704863
    [Abstract] [Full Text] [Related]

  • 5. C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
    Karreth FA, DeNicola GM, Winter SP, Tuveson DA.
    Mol Cell; 2009 Nov 13; 36(3):477-86. PubMed ID: 19917255
    [Abstract] [Full Text] [Related]

  • 6. Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway.
    Portis T, Longnecker R.
    Oncogene; 2004 Nov 11; 23(53):8619-28. PubMed ID: 15361852
    [Abstract] [Full Text] [Related]

  • 7. Constitutive activation of the Raf-MAPK pathway causes negative feedback inhibition of Ras-PI3K-AKT and cellular arrest through the EphA2 receptor.
    Menges CW, McCance DJ.
    Oncogene; 2008 May 01; 27(20):2934-40. PubMed ID: 18059341
    [Abstract] [Full Text] [Related]

  • 8. B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival.
    Matos P, Oliveira C, Velho S, Gonçalves V, da Costa LT, Moyer MP, Seruca R, Jordan P.
    Gastroenterology; 2008 Sep 01; 135(3):899-906. PubMed ID: 18602919
    [Abstract] [Full Text] [Related]

  • 9. Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1.
    Lucas L, Penalva V, Ramírez de Molina A, Del Peso L, Lacal JC.
    Int J Oncol; 2002 Sep 01; 21(3):477-85. PubMed ID: 12168089
    [Abstract] [Full Text] [Related]

  • 10. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression.
    Guerrero S, Casanova I, Farré L, Mazo A, Capellà G, Mangues R.
    Cancer Res; 2000 Dec 01; 60(23):6750-6. PubMed ID: 11118062
    [Abstract] [Full Text] [Related]

  • 11. BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
    Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R.
    J Pathol; 2008 Feb 01; 214(3):320-7. PubMed ID: 18098337
    [Abstract] [Full Text] [Related]

  • 12. Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity.
    Lue H, Thiele M, Franz J, Dahl E, Speckgens S, Leng L, Fingerle-Rowson G, Bucala R, Lüscher B, Bernhagen J.
    Oncogene; 2007 Aug 02; 26(35):5046-59. PubMed ID: 17310986
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of the PI3K-Akt/PKB survival pathway enhanced an ethanol extract of Rhus verniciflua Stokes-induced apoptosis via a mitochondrial pathway in AGS gastric cancer cell lines.
    Kim JH, Go HY, Jin DH, Kim HP, Hong MH, Chung WY, Park JH, Jang JB, Jung H, Shin YC, Kim SH, Ko SG.
    Cancer Lett; 2008 Jul 08; 265(2):197-205. PubMed ID: 18378393
    [Abstract] [Full Text] [Related]

  • 14. Involvement of PI3K-Akt-Bad pathway in apoptosis induced by 2,6-di-O-methyl-beta-cyclodextrin, not 2,6-di-O-methyl-alpha-cyclodextrin, through cholesterol depletion from lipid rafts on plasma membranes in cells.
    Motoyama K, Kameyama K, Onodera R, Araki N, Hirayama F, Uekama K, Arima H.
    Eur J Pharm Sci; 2009 Oct 08; 38(3):249-61. PubMed ID: 19664706
    [Abstract] [Full Text] [Related]

  • 15. Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process.
    Gallagher AP, Burnett AK, Bowen DT, Darley RL.
    Cancer Res; 1998 May 01; 58(9):2029-35. PubMed ID: 9581849
    [Abstract] [Full Text] [Related]

  • 16. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W.
    J Cell Physiol; 2009 Jul 01; 220(1):214-21. PubMed ID: 19288493
    [Abstract] [Full Text] [Related]

  • 17. Low dose leflunomide activates PI3K/Akt signalling in erythroleukemia cells and reduces apoptosis induced by anticancer agents.
    Leger DY, Liagre B, Beneytout JL.
    Apoptosis; 2006 Oct 01; 11(10):1747-60. PubMed ID: 16927021
    [Abstract] [Full Text] [Related]

  • 18. Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer.
    Kim D, Cheng GZ, Lindsley CW, Yang H, Cheng JQ.
    Curr Opin Investig Drugs; 2005 Dec 01; 6(12):1250-8. PubMed ID: 16370391
    [Abstract] [Full Text] [Related]

  • 19. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.
    Saleem M, Kaur S, Kweon MH, Adhami VM, Afaq F, Mukhtar H.
    Carcinogenesis; 2005 Nov 01; 26(11):1956-64. PubMed ID: 15958516
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells.
    Liang J, Ge F, Guo C, Luo G, Wang X, Han G, Zhang D, Wang J, Li K, Pan Y, Yao L, Yin Z, Guo X, Wu K, Ding J, Fan D.
    FEBS J; 2009 Feb 01; 276(3):685-94. PubMed ID: 19143835
    [Abstract] [Full Text] [Related]

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