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621 related items for PubMed ID: 19706767

  • 1. 17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells.
    Wang Y, Ma X, Yan S, Shen S, Zhu H, Gu Y, Wang H, Qin G, Yu Q.
    Cancer Res; 2009 Sep 15; 69(18):7302-10. PubMed ID: 19706767
    [Abstract] [Full Text] [Related]

  • 2. Jolkinolide B from Euphorbia fischeriana Steud induces in human leukemic cells apoptosis via JAK2/STAT3 pathways.
    Wang JH, Zhang K, Niu HY, Shu LH, Yue DM, Li D, He P.
    Int J Clin Pharmacol Ther; 2013 Mar 15; 51(3):170-8. PubMed ID: 23253949
    [Abstract] [Full Text] [Related]

  • 3. Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.
    Pedranzini L, Dechow T, Berishaj M, Comenzo R, Zhou P, Azare J, Bornmann W, Bromberg J.
    Cancer Res; 2006 Oct 01; 66(19):9714-21. PubMed ID: 17018630
    [Abstract] [Full Text] [Related]

  • 4. JAK/STAT pathway plays a critical role in the proinflammatory gene expression and apoptosis of RAW264.7 cells induced by trichothecenes as DON and T-2 toxin.
    Wang X, Liu Q, Ihsan A, Huang L, Dai M, Hao H, Cheng G, Liu Z, Wang Y, Yuan Z.
    Toxicol Sci; 2012 Jun 01; 127(2):412-24. PubMed ID: 22454431
    [Abstract] [Full Text] [Related]

  • 5. Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.
    Kreis S, Munz GA, Haan S, Heinrich PC, Behrmann I.
    Mol Cancer Res; 2007 Dec 01; 5(12):1331-41. PubMed ID: 18171991
    [Abstract] [Full Text] [Related]

  • 6. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
    Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV.
    Mol Pharmacol; 2007 Nov 01; 72(5):1137-45. PubMed ID: 17675586
    [Abstract] [Full Text] [Related]

  • 7. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
    Duan Z, Bradner JE, Greenberg E, Levine R, Foster R, Mahoney J, Seiden MV.
    Clin Cancer Res; 2006 Nov 15; 12(22):6844-52. PubMed ID: 17121906
    [Abstract] [Full Text] [Related]

  • 8. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.
    Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR.
    Clin Exp Pharmacol Physiol; 2010 Aug 15; 37(8):833-40. PubMed ID: 20456425
    [Abstract] [Full Text] [Related]

  • 9. Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases.
    Liu M, Xiao C, Sun M, Tan M, Hu L, Yu Q.
    Molecules; 2018 Jun 19; 23(6):. PubMed ID: 29921758
    [Abstract] [Full Text] [Related]

  • 10. IL-6 regulates MMP-10 expression via JAK2/STAT3 signaling pathway in a human lung adenocarcinoma cell line.
    Zhang X, Yin P, DI D, Luo G, Zheng L, Wei J, Zhang J, Shi Y, Zhang J, Xu N.
    Anticancer Res; 2009 Nov 19; 29(11):4497-501. PubMed ID: 20032397
    [Abstract] [Full Text] [Related]

  • 11. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul 19; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 12. Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells.
    Fuke H, Shiraki K, Sugimoto K, Tanaka J, Beppu T, Yoneda K, Yamamoto N, Ito K, Masuya M, Takei Y.
    Biochem Biophys Res Commun; 2007 Nov 23; 363(3):738-44. PubMed ID: 17904524
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin.
    Zhou J, Ong CN, Hur GM, Shen HM.
    Biochem Pharmacol; 2010 May 01; 79(9):1242-50. PubMed ID: 20026083
    [Abstract] [Full Text] [Related]

  • 14. Contribution of STAT3 to the activation of survivin by GM-CSF in CD34+ cell lines.
    Gu L, Chiang KY, Zhu N, Findley HW, Zhou M.
    Exp Hematol; 2007 Jun 01; 35(6):957-66. PubMed ID: 17533050
    [Abstract] [Full Text] [Related]

  • 15. STAT1 and STAT3 phosphorylation by porins are independent of JAKs but are dependent on MAPK pathway and plays a role in U937 cells production of interleukin-6.
    Galdiero M, Vitiello M, D'Isanto M, Raieta K, Galdiero E.
    Cytokine; 2006 Dec 01; 36(5-6):218-28. PubMed ID: 17258468
    [Abstract] [Full Text] [Related]

  • 16. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.
    Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.
    J Cell Physiol; 2012 May 01; 227(5):2184-95. PubMed ID: 21792937
    [Abstract] [Full Text] [Related]

  • 17. Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells.
    Huang JS, Guh JY, Hung WC, Yang ML, Lai YH, Chen HC, Chuang LY.
    Biochem J; 1999 Aug 15; 342 ( Pt 1)(Pt 1):231-8. PubMed ID: 10432321
    [Abstract] [Full Text] [Related]

  • 18. Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells.
    Wu X, Yan Q, Zhang Z, Du G, Wan X.
    Oncol Rep; 2012 May 15; 27(5):1488-96. PubMed ID: 22327423
    [Abstract] [Full Text] [Related]

  • 19. Janus activated kinase 2/signal transducer and activator of transcription 3 pathway mediates icariside II-induced apoptosis in U266 multiple myeloma cells.
    Kim SH, Ahn KS, Jeong SJ, Kwon TR, Jung JH, Yun SM, Han I, Lee SG, Kim DK, Kang M, Chen CY, Lee JW, Kim SH.
    Eur J Pharmacol; 2011 Mar 01; 654(1):10-6. PubMed ID: 21172343
    [Abstract] [Full Text] [Related]

  • 20. Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells.
    Zhang HH, Kuang S, Wang Y, Sun XX, Gu Y, Hu LH, Yu Q.
    Acta Pharmacol Sin; 2015 Apr 01; 36(4):507-16. PubMed ID: 25619393
    [Abstract] [Full Text] [Related]

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