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Journal Abstract Search

368 related items for PubMed ID: 19717305

  • 1. Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics.
    Makhaeva GF, Aksinenko AY, Sokolov VB, Serebryakova OG, Richardson RJ.
    Bioorg Med Chem Lett; 2009 Oct 01; 19(19):5528-30. PubMed ID: 19717305
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  • 2. Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors.
    Takahashi J, Hijikuro I, Kihara T, Murugesh MG, Fuse S, Kunimoto R, Tsumura Y, Akaike A, Niidome T, Okuno Y, Takahashi T, Sugimoto H.
    Bioorg Med Chem Lett; 2010 Mar 01; 20(5):1718-20. PubMed ID: 20137934
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  • 3. Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors.
    Takahashi J, Hijikuro I, Kihara T, Murugesh MG, Fuse S, Tsumura Y, Akaike A, Niidome T, Takahashi T, Sugimoto H.
    Bioorg Med Chem Lett; 2010 Mar 01; 20(5):1721-3. PubMed ID: 20137941
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  • 4. Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase.
    Huang L, Luo Z, He F, Lu J, Li X.
    Bioorg Med Chem; 2010 Jun 15; 18(12):4475-84. PubMed ID: 20471843
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  • 6. Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles.
    Samadi A, Marco-Contelles J, Soriano E, Alvarez-Pérez M, Chioua M, Romero A, González-Lafuente L, Gandía L, Roda JM, López MG, Villarroya M, García AG, Ríos Cde L.
    Bioorg Med Chem; 2010 Aug 15; 18(16):5861-72. PubMed ID: 20656495
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  • 9. Synthesis and evaluation of novel 4-[(3H,3aH,6aH)-3-phenyl)-4,6-dioxo-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazol-5(3H,6H,6aH)-yl]benzoic acid derivatives as potent acetylcholinesterase inhibitors and anti-amnestic agents.
    Anand P, Singh B.
    Bioorg Med Chem; 2012 Jan 01; 20(1):521-30. PubMed ID: 22172310
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  • 10. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Shan WJ, Huang L, Zhou Q, Meng FC, Li XS.
    Eur J Med Chem; 2011 Dec 01; 46(12):5885-93. PubMed ID: 22019228
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  • 12. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
    Kwon YE, Park JY, No KT, Shin JH, Lee SK, Eun JS, Yang JH, Shin TY, Kim DK, Chae BS, Leem JY, Kim KH.
    Bioorg Med Chem; 2007 Oct 15; 15(20):6596-607. PubMed ID: 17681794
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  • 13. Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.
    Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ.
    J Med Chem; 1999 Aug 26; 42(17):3227-42. PubMed ID: 10464010
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  • 14. Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase.
    Catto M, Pisani L, Leonetti F, Nicolotti O, Pesce P, Stefanachi A, Cellamare S, Carotti A.
    Bioorg Med Chem; 2013 Jan 01; 21(1):146-52. PubMed ID: 23199476
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  • 18. Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease.
    Yu Q, Holloway HW, Utsuki T, Brossi A, Greig NH.
    J Med Chem; 1999 May 20; 42(10):1855-61. PubMed ID: 10346939
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  • 20. Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
    Arce MP, Rodríguez-Franco MI, González-Muñoz GC, Pérez C, López B, Villarroya M, López MG, García AG, Conde S.
    J Med Chem; 2009 Nov 26; 52(22):7249-57. PubMed ID: 19856923
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