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Journal Abstract Search

520 related items for PubMed ID: 19739673

  • 1. Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.
    Poirier A, Funk C, Scherrmann JM, Lavé T.
    Mol Pharm; 2009; 6(6):1716-33. PubMed ID: 19739673
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  • 2. Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.
    Poirier A, Lavé T, Portmann R, Brun ME, Senner F, Kansy M, Grimm HP, Funk C.
    Drug Metab Dispos; 2008 Dec; 36(12):2434-44. PubMed ID: 18809732
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  • 3. Prediction of pharmacokinetic profile of valsartan in humans based on in vitro uptake-transport data.
    Poirier A, Cascais AC, Funk C, Lavé T.
    Chem Biodivers; 2009 Nov; 6(11):1975-87. PubMed ID: 19937834
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  • 7. Kinetic study of the hepatobiliary transport of a new prostaglandin receptor agonist.
    Imawaka H, Sugiyama Y.
    J Pharmacol Exp Ther; 1998 Mar; 284(3):949-57. PubMed ID: 9495854
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  • 10. Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.
    Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS.
    Drug Metab Dispos; 2012 May; 40(5):1007-17. PubMed ID: 22344703
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  • 12. Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs.
    Sjögren E, Hedeland M, Bondesson U, Lennernäs H.
    Eur J Pharm Sci; 2014 Jun 16; 57():214-23. PubMed ID: 24075962
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  • 14. Inhibition of biliary excretion of methotrexate by probenecid in rats: quantitative prediction of interaction from in vitro data.
    Ueda K, Kato Y, Komatsu K, Sugiyama Y.
    J Pharmacol Exp Ther; 2001 Jun 16; 297(3):1036-43. PubMed ID: 11356926
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  • 16. Kinetic characterization of rat hepatic uptake of 16 actively transported drugs.
    Yabe Y, Galetin A, Houston JB.
    Drug Metab Dispos; 2011 Oct 16; 39(10):1808-14. PubMed ID: 21730030
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  • 19. P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.
    Tahara H, Kusuhara H, Fuse E, Sugiyama Y.
    Drug Metab Dispos; 2005 Jul 16; 33(7):963-8. PubMed ID: 15821041
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  • 20. Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs.
    De Buck SS, Sinha VK, Fenu LA, Nijsen MJ, Mackie CE, Gilissen RA.
    Drug Metab Dispos; 2007 Oct 16; 35(10):1766-80. PubMed ID: 17620347
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