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Journal Abstract Search

959 related items for PubMed ID: 19740433

  • 1. Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis.
    Wendt MK, Schiemann WP.
    Breast Cancer Res; 2009; 11(5):R68. PubMed ID: 19740433
    [Abstract] [Full Text] [Related]

  • 2. Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells.
    Galliher AJ, Schiemann WP.
    Breast Cancer Res; 2006; 8(4):R42. PubMed ID: 16859511
    [Abstract] [Full Text] [Related]

  • 3. Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression.
    Wendt MK, Smith JA, Schiemann WP.
    Oncogene; 2010 Dec 09; 29(49):6485-98. PubMed ID: 20802523
    [Abstract] [Full Text] [Related]

  • 4. Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion.
    Galliher AJ, Schiemann WP.
    Cancer Res; 2007 Apr 15; 67(8):3752-8. PubMed ID: 17440088
    [Abstract] [Full Text] [Related]

  • 5. Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta.
    Galliher-Beckley AJ, Schiemann WP.
    Carcinogenesis; 2008 Feb 15; 29(2):244-51. PubMed ID: 18174260
    [Abstract] [Full Text] [Related]

  • 6. Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β.
    Parvani JG, Galliher-Beckley AJ, Schiemann BJ, Schiemann WP.
    Mol Biol Cell; 2013 Nov 15; 24(21):3449-59. PubMed ID: 24006485
    [Abstract] [Full Text] [Related]

  • 7. p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.
    Wendt MK, Smith JA, Schiemann WP.
    J Biol Chem; 2009 Dec 04; 284(49):34145-56. PubMed ID: 19822523
    [Abstract] [Full Text] [Related]

  • 8. The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors.
    Ungefroren H, Sebens S, Groth S, Gieseler F, Fändrich F.
    Curr Cancer Drug Targets; 2011 May 04; 11(4):524-35. PubMed ID: 21395548
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.
    Shinto O, Yashiro M, Kawajiri H, Shimizu K, Shimizu T, Miwa A, Hirakawa K.
    Br J Cancer; 2010 Mar 02; 102(5):844-51. PubMed ID: 20145621
    [Abstract] [Full Text] [Related]

  • 10. Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells.
    Taylor MA, Amin JD, Kirschmann DA, Schiemann WP.
    Neoplasia; 2011 May 02; 13(5):406-18. PubMed ID: 21532881
    [Abstract] [Full Text] [Related]

  • 11. Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms.
    Walsh MF, Ampasala DR, Hatfield J, Vander Heide R, Suer S, Rishi AK, Basson MD.
    Am J Pathol; 2008 Aug 02; 173(2):385-99. PubMed ID: 18583311
    [Abstract] [Full Text] [Related]

  • 12. An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.
    Park CY, Min KN, Son JY, Park SY, Nam JS, Kim DK, Sheen YY.
    Cancer Lett; 2014 Aug 28; 351(1):72-80. PubMed ID: 24887560
    [Abstract] [Full Text] [Related]

  • 13. TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer.
    Wendt MK, Schiemann BJ, Parvani JG, Lee YH, Kang Y, Schiemann WP.
    Oncogene; 2013 Apr 18; 32(16):2005-15. PubMed ID: 22710711
    [Abstract] [Full Text] [Related]

  • 14. Src activation is not necessary for transforming growth factor (TGF)-beta-mediated epithelial to mesenchymal transitions (EMT) in mammary epithelial cells. PP1 directly inhibits TGF-beta receptors I and II.
    Maeda M, Shintani Y, Wheelock MJ, Johnson KR.
    J Biol Chem; 2006 Jan 06; 281(1):59-68. PubMed ID: 16267045
    [Abstract] [Full Text] [Related]

  • 15. Twist induces epithelial-mesenchymal transition and cell motility in breast cancer via ITGB1-FAK/ILK signaling axis and its associated downstream network.
    Yang J, Hou Y, Zhou M, Wen S, Zhou J, Xu L, Tang X, Du YE, Hu P, Liu M.
    Int J Biochem Cell Biol; 2016 Feb 06; 71():62-71. PubMed ID: 26693891
    [Abstract] [Full Text] [Related]

  • 16. EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells.
    Park CY, Kim DK, Sheen YY.
    Cancer Sci; 2011 Oct 06; 102(10):1889-96. PubMed ID: 21707864
    [Abstract] [Full Text] [Related]

  • 17. TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression.
    Daroqui MC, Vazquez P, Bal de Kier Joffé E, Bakin AV, Puricelli LI.
    Oncol Rep; 2012 Aug 06; 28(2):567-75. PubMed ID: 22614218
    [Abstract] [Full Text] [Related]

  • 18. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G, Schwarz RE, Higgins L, McEnroe G, Chakravarty S, Dugar S, Reiss M.
    Cancer Res; 2004 Aug 01; 64(15):5200-11. PubMed ID: 15289325
    [Abstract] [Full Text] [Related]

  • 19. Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.
    Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL.
    Breast Cancer Res; 2012 Jul 02; 14(4):R98. PubMed ID: 22748014
    [Abstract] [Full Text] [Related]

  • 20. Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion.
    Cheng N, Chytil A, Shyr Y, Joly A, Moses HL.
    Mol Cancer Res; 2008 Oct 02; 6(10):1521-33. PubMed ID: 18922968
    [Abstract] [Full Text] [Related]

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