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577 related items for PubMed ID: 1974199

  • 1. Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450.
    Veronese ME, McManus ME, Laupattarakasem P, Miners JO, Birkett DJ.
    Drug Metab Dispos; 1990; 18(3):356-61. PubMed ID: 1974199
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of N-nitroso-2,6-dimethylmorpholine by isozymes of rabbit liver microsomal cytochrome P-450.
    Kokkinakis DM, Koop DR, Scarpelli DG, Coon MJ, Hollenberg PF.
    Cancer Res; 1985 Feb; 45(2):619-24. PubMed ID: 3967237
    [Abstract] [Full Text] [Related]

  • 3. Reconstitution of rabbit liver microsomal N-nitrosopyrrolidine alpha-hydroxylase activity.
    McCoy GD, Koop DR.
    Cancer Res; 1988 Jul 15; 48(14):3987-92. PubMed ID: 3383193
    [Abstract] [Full Text] [Related]

  • 4. Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition.
    Knodell RG, Hall SD, Wilkinson GR, Guengerich FP.
    J Pharmacol Exp Ther; 1987 Jun 15; 241(3):1112-9. PubMed ID: 3598900
    [Abstract] [Full Text] [Related]

  • 5. Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.
    Jeffery EH, Mannering GJ.
    Mol Pharmacol; 1983 May 15; 23(3):748-57. PubMed ID: 6865917
    [Abstract] [Full Text] [Related]

  • 6. Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
    Yun CH, Shimada T, Guengerich FP.
    Cancer Res; 1992 Apr 01; 52(7):1868-74. PubMed ID: 1551116
    [Abstract] [Full Text] [Related]

  • 7. N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.
    Cribb AE, Spielberg SP, Griffin GP.
    Drug Metab Dispos; 1995 Mar 01; 23(3):406-14. PubMed ID: 7628308
    [Abstract] [Full Text] [Related]

  • 8. Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.
    Suzuki T, Narimatsu S, Fujita S, Masubuchi Y, Umeda S, Imaoka S, Funae Y.
    Drug Metab Dispos; 1992 Mar 01; 20(3):367-73. PubMed ID: 1355709
    [Abstract] [Full Text] [Related]

  • 9. The characteristics of the microsomal hydroxylation of tolbutamide.
    Bélanger PM, St-Hilaire S.
    Can J Physiol Pharmacol; 1991 Mar 01; 69(3):400-5. PubMed ID: 2059905
    [Abstract] [Full Text] [Related]

  • 10. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR, Lasker JM, Johnson EF, Raucy JL.
    Drug Metab Dispos; 2000 Mar 01; 28(3):354-9. PubMed ID: 10681382
    [Abstract] [Full Text] [Related]

  • 11. Identification of cytochrome P-450 isozymes involved in the hydroxylation of dantrolene by rat liver microsomes.
    Jayyosi Z, Villoutreix J, Ziegler JM, Batt AM, De Maack F, Siest G, Thomas PE.
    Drug Metab Dispos; 1993 Mar 01; 21(5):939-45. PubMed ID: 7902259
    [Abstract] [Full Text] [Related]

  • 12. Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-alpha-(2-methylazo)-p-toluamide, the azo derivative of procarbazine.
    Prough RA, Brown MI, Dannan GA, Guengerich FP.
    Cancer Res; 1984 Feb 01; 44(2):543-8. PubMed ID: 6692359
    [Abstract] [Full Text] [Related]

  • 13. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
    Suzuki T, Fujita S, Narimatsu S, Masubuchi Y, Tachibana M, Ohta S, Hirobe M.
    FASEB J; 1992 Jan 06; 6(2):771-6. PubMed ID: 1537468
    [Abstract] [Full Text] [Related]

  • 14. Stimulation of tolbutamide hydroxylation by acetone and acetonitrile in human liver microsomes and in a cytochrome P-450 2C9-reconstituted system.
    Palamanda J, Feng WW, Lin CC, Nomeir AA.
    Drug Metab Dispos; 2000 Jan 06; 28(1):38-43. PubMed ID: 10611138
    [Abstract] [Full Text] [Related]

  • 15. Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not N-dealkylation of diazepam and temazepam.
    Reilly PE, Thompson DA, Mason SR, Hooper WD.
    Mol Pharmacol; 1990 May 06; 37(5):767-74. PubMed ID: 1971091
    [Abstract] [Full Text] [Related]

  • 16. Immunochemical detection and quantitation of microsomal cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate:cytochrome P-450 reductase in the rat ventral prostate.
    Haaparanta T, Halpert J, Glaumann H, Gustafsson JA.
    Cancer Res; 1983 Nov 06; 43(11):5131-7. PubMed ID: 6413054
    [Abstract] [Full Text] [Related]

  • 17. Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a.
    Koop DR.
    Mol Pharmacol; 1986 Apr 06; 29(4):399-404. PubMed ID: 3702859
    [Abstract] [Full Text] [Related]

  • 18. Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine.
    Baba T, Yamada H, Oguri K, Yoshimura H.
    Xenobiotica; 1988 May 06; 18(5):475-84. PubMed ID: 3135673
    [Abstract] [Full Text] [Related]

  • 19. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
    Pichard L, Gillet G, Fabre I, Dalet-Beluche I, Bonfils C, Thenot JP, Maurel P.
    Drug Metab Dispos; 1990 May 06; 18(5):711-9. PubMed ID: 1981725
    [Abstract] [Full Text] [Related]

  • 20. The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation.
    Meyer UA, Gut J, Kronbach T, Skoda C, Meier UT, Catin T, Dayer P.
    Xenobiotica; 1986 May 06; 16(5):449-64. PubMed ID: 2874666
    [Abstract] [Full Text] [Related]


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