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263 related items for PubMed ID: 19751394

  • 1. Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.
    Labrie V, Wang W, Barger SW, Baker GB, Roder JC.
    Genes Brain Behav; 2010 Feb; 9(1):11-25. PubMed ID: 19751394
    [Abstract] [Full Text] [Related]

  • 2. Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors.
    Labrie V, Clapcote SJ, Roder JC.
    Pharmacol Biochem Behav; 2009 Feb; 91(4):610-20. PubMed ID: 18940194
    [Abstract] [Full Text] [Related]

  • 3. Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.
    Labrie V, Lipina T, Roder JC.
    Psychopharmacology (Berl); 2008 Oct; 200(2):217-30. PubMed ID: 18597079
    [Abstract] [Full Text] [Related]

  • 4. Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice.
    Labrie V, Duffy S, Wang W, Barger SW, Baker GB, Roder JC.
    Learn Mem; 2009 Jan; 16(1):28-37. PubMed ID: 19117914
    [Abstract] [Full Text] [Related]

  • 5. Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.
    Ballard TM, Pauly-Evers M, Higgins GA, Ouagazzal AM, Mutel V, Borroni E, Kemp JA, Bluethmann H, Kew JN.
    J Neurosci; 2002 Aug 01; 22(15):6713-23. PubMed ID: 12151550
    [Abstract] [Full Text] [Related]

  • 6. D-Amino acids in the brain and mutant rodents lacking D-amino-acid oxidase activity.
    Yamanaka M, Miyoshi Y, Ohide H, Hamase K, Konno R.
    Amino Acids; 2012 Nov 01; 43(5):1811-21. PubMed ID: 22892863
    [Abstract] [Full Text] [Related]

  • 7. The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia.
    Labrie V, Roder JC.
    Neurosci Biobehav Rev; 2010 Mar 01; 34(3):351-72. PubMed ID: 19695284
    [Abstract] [Full Text] [Related]

  • 8. The neurobiology of D-amino acid oxidase and its involvement in schizophrenia.
    Verrall L, Burnet PW, Betts JF, Harrison PJ.
    Mol Psychiatry; 2010 Feb 01; 15(2):122-37. PubMed ID: 19786963
    [Abstract] [Full Text] [Related]

  • 9. Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.
    Pritchett D, Taylor AM, Barkus C, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Peirson SN, Bannerman DM.
    Eur J Neurosci; 2016 Apr 01; 43(7):979-89. PubMed ID: 26833794
    [Abstract] [Full Text] [Related]

  • 10. Behavioral and biochemical characterization of a mutant mouse strain lacking D-amino acid oxidase activity and its implications for schizophrenia.
    Almond SL, Fradley RL, Armstrong EJ, Heavens RB, Rutter AR, Newman RJ, Chiu CS, Konno R, Hutson PH, Brandon NJ.
    Mol Cell Neurosci; 2006 Aug 01; 32(4):324-34. PubMed ID: 16843004
    [Abstract] [Full Text] [Related]

  • 11. Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors.
    Haradahira T, Okauchi T, Maeda J, Zhang MR, Nishikawa T, Konno R, Suzuki K, Suhara T.
    Synapse; 2003 Nov 01; 50(2):130-6. PubMed ID: 12923815
    [Abstract] [Full Text] [Related]

  • 12. Modulating NMDA Receptor Function with D-Amino Acid Oxidase Inhibitors: Understanding Functional Activity in PCP-Treated Mouse Model.
    Sershen H, Hashim A, Dunlop DS, Suckow RF, Cooper TB, Javitt DC.
    Neurochem Res; 2016 Feb 01; 41(1-2):398-408. PubMed ID: 26857796
    [Abstract] [Full Text] [Related]

  • 13. Retinal NMDA receptor function and expression are altered in a mouse lacking D-amino acid oxidase.
    Gustafson EC, Morgans CW, Tekmen M, Sullivan SJ, Esguerra M, Konno R, Miller RF.
    J Neurophysiol; 2013 Dec 01; 110(12):2718-26. PubMed ID: 24068757
    [Abstract] [Full Text] [Related]

  • 14. D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
    Popiolek M, Ross JF, Charych E, Chanda P, Gundelfinger ED, Moss SJ, Brandon NJ, Pausch MH.
    J Biol Chem; 2011 Aug 19; 286(33):28867-28875. PubMed ID: 21700703
    [Abstract] [Full Text] [Related]

  • 15. D-amino acid oxidase knockdown in the mouse cerebellum reduces NR2A mRNA.
    Burnet PW, Anderson PN, Chen L, Nikiforova N, Harrison PJ, Wood MJ.
    Mol Cell Neurosci; 2011 Jan 19; 46(1):167-75. PubMed ID: 20828614
    [Abstract] [Full Text] [Related]

  • 16. Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia.
    Halene TB, Ehrlichman RS, Liang Y, Christian EP, Jonak GJ, Gur TL, Blendy JA, Dow HC, Brodkin ES, Schneider F, Gur RC, Siegel SJ.
    Genes Brain Behav; 2009 Oct 19; 8(7):661-75. PubMed ID: 19563516
    [Abstract] [Full Text] [Related]

  • 17. Schizophrenia-like phenotypes in mice with NMDA receptor ablation in intralaminar thalamic nucleus cells and gene therapy-based reversal in adults.
    Yasuda K, Hayashi Y, Yoshida T, Kashiwagi M, Nakagawa N, Michikawa T, Tanaka M, Ando R, Huang A, Hosoya T, McHugh TJ, Kuwahara M, Itohara S.
    Transl Psychiatry; 2017 Feb 28; 7(2):e1047. PubMed ID: 28244984
    [Abstract] [Full Text] [Related]

  • 18. Behavioral characterization of a mutant mouse strain lacking D-amino acid oxidase activity.
    Zhang M, Ballard ME, Basso AM, Bratcher N, Browman KE, Curzon P, Konno R, Meyer AH, Rueter LE.
    Behav Brain Res; 2011 Feb 02; 217(1):81-7. PubMed ID: 20933022
    [Abstract] [Full Text] [Related]

  • 19. Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.
    Howley E, Bestwick M, Fradley R, Harrison H, Leveridge M, Okada K, Fieldhouse C, Farnaby W, Canning H, Sykes AP, Merchant K, Hazel K, Kerr C, Kinsella N, Walsh L, Livermore DG, Hoffman I, Ellery J, Mitchell P, Patel T, Carlton M, Barnes M, Miller DJ.
    Neurochem Res; 2017 Nov 02; 42(11):3279-3288. PubMed ID: 28780732
    [Abstract] [Full Text] [Related]

  • 20. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.
    Labrie V, Fukumura R, Rastogi A, Fick LJ, Wang W, Boutros PC, Kennedy JL, Semeralul MO, Lee FH, Baker GB, Belsham DD, Barger SW, Gondo Y, Wong AH, Roder JC.
    Hum Mol Genet; 2009 Sep 01; 18(17):3227-43. PubMed ID: 19483194
    [Abstract] [Full Text] [Related]

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