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Journal Abstract Search


141 related items for PubMed ID: 1976059

  • 21. Inhibition of oxidative drug metabolism by orphenadrine: in vitro and in vivo evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics.
    Reidy GF, Mehta I, Murray M.
    Mol Pharmacol; 1989 May; 35(5):736-43. PubMed ID: 2725477
    [Abstract] [Full Text] [Related]

  • 22. Cytochrome P-450 isozymes 2 and 5 in rabbit lung and liver. Comparisons of structure and inducibility.
    Parandoosh Z, Fujita VS, Coon MJ, Philpot RM.
    Drug Metab Dispos; 1987 May; 15(1):59-67. PubMed ID: 2881760
    [Abstract] [Full Text] [Related]

  • 23. The effect of substrate on the expression of activity catalyzed by cytochrome P-450: metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems.
    Domin BA, Philpot RM.
    Arch Biochem Biophys; 1986 Apr; 246(1):128-42. PubMed ID: 3963817
    [Abstract] [Full Text] [Related]

  • 24. Characterization of halothane oxidation by hepatic microsomes and purified cytochromes P-450 using a gas chromatographic mass spectrometric assay.
    Gruenke LD, Konopka K, Koop DR, Waskell LA.
    J Pharmacol Exp Ther; 1988 Aug; 246(2):454-9. PubMed ID: 3404442
    [Abstract] [Full Text] [Related]

  • 25. Studies on the rate-determining factor in testosterone hydroxylation by rat liver microsomal cytochrome P-450: evidence against cytochrome P-450 isozyme:isozyme interactions.
    Dutton DR, McMillen SK, Sonderfan AJ, Thomas PE, Parkinson A.
    Arch Biochem Biophys; 1987 Jun; 255(2):316-28. PubMed ID: 3109324
    [Abstract] [Full Text] [Related]

  • 26. Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal.
    Roberts ES, Vaz AD, Coon MJ.
    Mol Pharmacol; 1992 Feb; 41(2):427-33. PubMed ID: 1538719
    [Abstract] [Full Text] [Related]

  • 27. The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol.
    Wolf CR, Statham CN, McMenamin MG, Bend JR, Boyd MR, Philpot RM.
    Mol Pharmacol; 1982 Nov; 22(3):738-44. PubMed ID: 7155130
    [Abstract] [Full Text] [Related]

  • 28. Androgen-dependent renal microsomal cytochrome P-450 responsible for N-hydroxylation and mutagenic activation of 3-methoxy-4-aminoazobenzene in the BALB/c mouse.
    Degawa M, Miura S, Hashimoto Y.
    Cancer Res; 1990 May 01; 50(9):2729-33. PubMed ID: 2328499
    [Abstract] [Full Text] [Related]

  • 29. N-aralkyl derivatives of 1-aminobenzotriazole as potent isozyme-selective mechanism-based inhibitors of rabbit pulmonary cytochrome P450 in vivo.
    Mathews JM, Bend JR.
    J Pharmacol Exp Ther; 1993 Apr 01; 265(1):281-5. PubMed ID: 8474011
    [Abstract] [Full Text] [Related]

  • 30. Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral.
    Raner GM, Vaz AD, Coon MJ.
    Mol Pharmacol; 1996 Mar 01; 49(3):515-22. PubMed ID: 8643091
    [Abstract] [Full Text] [Related]

  • 31. Formation of hydroxy derivatives, aldehydes, and nitrite from N-nitrosomethyl-n-amylamine by rat liver microsomes and by purified cytochrome P-450 IIB1.
    Ji C, Mirvish SS, Nickols J, Ishizaki H, Lee MJ, Yang CS.
    Cancer Res; 1989 Oct 01; 49(19):5299-304. PubMed ID: 2766298
    [Abstract] [Full Text] [Related]

  • 32. Cytochrome P450 isozymes involved in aromatic hydroxylation and side-chain N-desisopropylation of alprenolol in rat liver microsomes.
    Narimatsu S, Tachibana M, Masubuchi Y, Imaoka S, Funae Y, Suzuki T.
    Biol Pharm Bull; 1995 Aug 01; 18(8):1060-5. PubMed ID: 8535396
    [Abstract] [Full Text] [Related]

  • 33. Identification of the enzymes catalyzing metabolism of methoxyflurane.
    Waskell L, Canova-Davis E, Philpot R, Parandoush Z, Chiang JY.
    Drug Metab Dispos; 1986 Aug 01; 14(6):643-8. PubMed ID: 2877820
    [Abstract] [Full Text] [Related]

  • 34. The relationship between increases in the hepatic content of cytochrome P-450, form 5, and in the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbital.
    Robertson IG, Serabjit-Singh C, Croft JE, Philpot RM.
    Mol Pharmacol; 1983 Jul 01; 24(1):156-62. PubMed ID: 6865923
    [Abstract] [Full Text] [Related]

  • 35. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. II. Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of mouse, hamster, rat and rhesus monkey.
    Buckpitt A, Buonarati M, Avey LB, Chang AM, Morin D, Plopper CG.
    J Pharmacol Exp Ther; 1992 Apr 01; 261(1):364-72. PubMed ID: 1560380
    [Abstract] [Full Text] [Related]

  • 36. Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: characterization of high- and low-affinity pyridine N-oxygenases.
    Kim SG, Philpot RM, Novak RF.
    J Pharmacol Exp Ther; 1991 Oct 01; 259(1):470-7. PubMed ID: 1920133
    [Abstract] [Full Text] [Related]

  • 37. Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5.
    Waxman DJ, Walsh C.
    Biochemistry; 1983 Sep 27; 22(20):4846-55. PubMed ID: 6626536
    [Abstract] [Full Text] [Related]

  • 38. Enzyme kinetics of N-nitrosodimethylamine demethylase in rodents and humans.
    Yoo JS, Ishizaki H, Yang CS.
    IARC Sci Publ; 1991 Sep 27; (105):366-9. PubMed ID: 1855882
    [Abstract] [Full Text] [Related]

  • 39. Hydroxylation of prostaglandins by inducible isozymes of rabbit liver microsomal cytochrome P-450. Participation of cytochrome b5.
    Vatsis KP, Theoharides AD, Kupfer D, Coon MJ.
    J Biol Chem; 1982 Oct 10; 257(19):11221-9. PubMed ID: 6889595
    [Abstract] [Full Text] [Related]

  • 40. Rat lung and liver cytochrome P-450 isozymes involved in the hydroxylation of m-xylene.
    Toftgård R, Haaparanta T, Halpert J.
    Toxicology; 1986 Jun 10; 39(3):225-31. PubMed ID: 3705085
    [Abstract] [Full Text] [Related]


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