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Journal Abstract Search

369 related items for PubMed ID: 19764786

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  • 2. Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(-/-) rats.
    Nagaya Y, Nozaki Y, Takenaka O, Watari R, Kusano K, Yoshimura T, Kusuhara H.
    Drug Metab Pharmacokinet; 2016 Feb; 31(1):57-66. PubMed ID: 26830080
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  • 4. Brain distribution of cetirizine enantiomers: comparison of three different tissue-to-plasma partition coefficients: K(p), K(p,u), and K(p,uu).
    Gupta A, Chatelain P, Massingham R, Jonsson EN, Hammarlund-Udenaes M.
    Drug Metab Dispos; 2006 Feb; 34(2):318-23. PubMed ID: 16303872
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  • 6. Unbound drug concentration in brain homogenate and cerebral spinal fluid at steady state as a surrogate for unbound concentration in brain interstitial fluid.
    Liu X, Van Natta K, Yeo H, Vilenski O, Weller PE, Worboys PD, Monshouwer M.
    Drug Metab Dispos; 2009 Apr; 37(4):787-93. PubMed ID: 19116265
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  • 8. Effect of P-glycoprotein-mediated efflux on cerebrospinal fluid/plasma concentration ratio.
    Ohe T, Sato M, Tanaka S, Fujino N, Hata M, Shibata Y, Kanatani A, Fukami T, Yamazaki M, Chiba M, Ishii Y.
    Drug Metab Dispos; 2003 Oct; 31(10):1251-4. PubMed ID: 12975334
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  • 10. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics.
    Shen DD, Artru AA, Adkison KK.
    Adv Drug Deliv Rev; 2004 Oct 14; 56(12):1825-57. PubMed ID: 15381336
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  • 13. Central nervous system distribution kinetics of indinavir in rats.
    Hamidi M.
    J Pharm Pharmacol; 2007 Aug 14; 59(8):1077-85. PubMed ID: 17725849
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  • 15. Estimation of the unbound brain concentration of P-glycoprotein substrates or nonsubstrates by a serial cerebrospinal fluid sampling technique in rats.
    Mariappan TT, Kurawattimath V, Gautam SS, Kulkarni CP, Kallem R, Taskar KS, Marathe PH, Mandlekar S.
    Mol Pharm; 2014 Feb 03; 11(2):477-85. PubMed ID: 24380373
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  • 18. Active-site concentrations of chemicals - are they a better predictor of effect than plasma/organ/tissue concentrations?
    Hammarlund-Udenaes M.
    Basic Clin Pharmacol Toxicol; 2010 Mar 03; 106(3):215-20. PubMed ID: 20050843
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  • 20. Pharmacokinetic modelling of blood-brain barrier transport of escitalopram in rats.
    Bundgaard C, Jørgensen M, Larsen F.
    Biopharm Drug Dispos; 2007 Oct 03; 28(7):349-60. PubMed ID: 17654695
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