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Journal Abstract Search

302 related items for PubMed ID: 19772293

  • 1. Discovery of a new class of protein farnesyltransferase inhibitors in the arylthiophene series.
    Lethu S, Ginisty M, Bosc D, Dubois J.
    J Med Chem; 2009 Oct 22; 52(20):6205-8. PubMed ID: 19772293
    [Abstract] [Full Text] [Related]

  • 2. Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.
    Nara S, Tanaka R, Eishima J, Hara M, Takahashi Y, Otaki S, Foglesong RJ, Hughes PF, Turkington S, Kanda Y.
    J Med Chem; 2003 Jun 05; 46(12):2467-73. PubMed ID: 12773050
    [Abstract] [Full Text] [Related]

  • 3. A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase.
    Aoyama T, Satoh T, Yonemoto M, Shibata J, Nonoshita K, Arai S, Kawakami K, Iwasawa Y, Sano H, Tanaka K, Monden Y, Kodera T, Arakawa H, Suzuki-Takahashi I, Kamei T, Tomimoto K.
    J Med Chem; 1998 Jan 15; 41(2):143-7. PubMed ID: 9457237
    [No Abstract] [Full Text] [Related]

  • 4. Discovery of potent inhibitor for farnesyl pyrophosphate synthase in the mevalonate pathway.
    Gao J, Chu X, Qiu Y, Wu L, Qiao Y, Wu J, Li D.
    Chem Commun (Camb); 2010 Aug 07; 46(29):5340-2. PubMed ID: 20544107
    [Abstract] [Full Text] [Related]

  • 5. Non-thiol farnesyltransferase inhibitors: FTase-inhibition and cellular activity of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors.
    Mitsch A, Bergemann S, Gust R, Sattler I, Schlitzer M.
    Arch Pharm (Weinheim); 2003 Jul 07; 336(4-5):242-50. PubMed ID: 12916059
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-I.
    Carrico D, Blaskovich MA, Bucher CJ, Sebti SM, Hamilton AD.
    Bioorg Med Chem; 2005 Feb 01; 13(3):677-88. PubMed ID: 15653335
    [Abstract] [Full Text] [Related]

  • 7. Potent and selective non-cysteine-containing inhibitors of protein farnesyltransferase.
    Augeri DJ, O'Connor SJ, Janowick D, Szczepankiewicz B, Sullivan G, Larsen J, Kalvin D, Cohen J, Devine E, Zhang H, Cherian S, Saeed B, Ng SC, Rosenberg S.
    J Med Chem; 1998 Oct 22; 41(22):4288-300. PubMed ID: 9784104
    [Abstract] [Full Text] [Related]

  • 8. Advances in the development of farnesyltransferase inhibitors: substrate recognition by protein farnesyltransferase.
    Yang W, Del Villar K, Urano J, Mitsuzawa H, Tamanoi F.
    J Cell Biochem Suppl; 1997 Oct 22; 27():12-9. PubMed ID: 9591188
    [Abstract] [Full Text] [Related]

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  • 10. New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis.
    Lethu S, Bosc D, Mouray E, Grellier P, Dubois J.
    J Enzyme Inhib Med Chem; 2013 Feb 22; 28(1):163-71. PubMed ID: 22233543
    [Abstract] [Full Text] [Related]

  • 11. Non-thiol farnesyltransferase inhibitors: utilization of the far aryl binding site by arylthienylacryloylaminobenzophenones.
    Mitsch A, Altenkämper M, Sattler I, Schlitzer M.
    Arch Pharm (Weinheim); 2005 Jan 22; 338(1):9-17. PubMed ID: 15674808
    [Abstract] [Full Text] [Related]

  • 12. Non-thiol farnesyltransferase inhibitors: N-(4-tolylacetylamino-3-benzoylphenyl)-3-arylfurylacrylic acid amides.
    Mitsch A, Wissner P, Silber K, Haebel P, Sattler I, Klebe G, Schlitzer M.
    Bioorg Med Chem; 2004 Sep 01; 12(17):4585-600. PubMed ID: 15358286
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of potential bisubstrate inhibitors of protein farnesyltransferase. Design and synthesis of functionalized imidazoles.
    de Figueiredo RM, Coudray L, Dubois J.
    Org Biomol Chem; 2007 Oct 21; 5(20):3299-309. PubMed ID: 17912382
    [Abstract] [Full Text] [Related]

  • 14. Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential.
    Tanaka R, Rubio A, Harn NK, Gernert D, Grese TA, Eishima J, Hara M, Yoda N, Ohashi R, Kuwabara T, Soga S, Akinaga S, Nara S, Kanda Y.
    Bioorg Med Chem; 2007 Feb 01; 15(3):1363-82. PubMed ID: 17127066
    [Abstract] [Full Text] [Related]

  • 15. Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies.
    Lin X, Murray JM, Rico AC, Wang MX, Chu DT, Zhou Y, Del Rosario M, Kaufman S, Ma S, Fang E, Crawford K, Jefferson AB.
    Bioorg Med Chem Lett; 2006 Aug 15; 16(16):4163-8. PubMed ID: 16765046
    [Abstract] [Full Text] [Related]

  • 16. Citrafungins A and B, two new fungal metabolite inhibitors of GGTase I with antifungal activity.
    Singh SB, Zink DL, Doss GA, Polishook JD, Ruby C, Register E, Kelly TM, Bonfiglio C, Williamson JM, Kelly R.
    Org Lett; 2004 Feb 05; 6(3):337-40. PubMed ID: 14748587
    [Abstract] [Full Text] [Related]

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  • 18. 7-imidazolylalkanamido-1-carboxylalkylbenzo-diazepine, a novel series of farnesyltransferase inhibitors.
    Wan SB, Chu FM, Guo ZR.
    Yao Xue Xue Bao; 2002 Jul 05; 37(7):516-21. PubMed ID: 12914320
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of 1-benzyl-5-(3-biphenyl-2-yl-propyl)-1H-imidazole as novel farnesyltransferase inhibitor.
    Lin NH, Wang L, Wang X, Wang GT, Cohen J, Gu WZ, Zhang H, Rosenberg SH, Sham HL.
    Bioorg Med Chem Lett; 2004 Oct 18; 14(20):5057-62. PubMed ID: 15380198
    [Abstract] [Full Text] [Related]

  • 20. 3-Aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a novel class of farnesyltransferase inhibitors.
    Lee H, Lee J, Shin Y, Jung W, Kim JH, Park K, Ro S, Chung HH, Koh JS.
    Bioorg Med Chem Lett; 2001 Nov 19; 11(22):2963-5. PubMed ID: 11677136
    [Abstract] [Full Text] [Related]

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