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1083 related items for PubMed ID: 19778239

  • 1. Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose.
    Shih TM, Skovira JW, O'Donnell JC, McDonough JH.
    Toxicol Mech Methods; 2009 Sep; 19(6-7):386-400. PubMed ID: 19778239
    [Abstract] [Full Text] [Related]

  • 2. In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs.
    Shih TM, Skovira JW, O'Donnell JC, McDonough JH.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):207-14. PubMed ID: 20223229
    [Abstract] [Full Text] [Related]

  • 3. An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K, Bajgar J.
    Clin Toxicol (Phila); 2009 Jan 06; 47(1):72-6. PubMed ID: 18686075
    [Abstract] [Full Text] [Related]

  • 4. Reactivation of brain acetylcholinesterase by monoisonitrosoacetone increases the therapeutic efficacy against nerve agents in guinea pigs.
    Skovira JW, O'Donnell JC, Koplovitz I, Kan RK, McDonough JH, Shih TM.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):318-24. PubMed ID: 20230808
    [Abstract] [Full Text] [Related]

  • 5. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J.
    Pharmazie; 2004 Oct 06; 59(10):795-8. PubMed ID: 15544060
    [Abstract] [Full Text] [Related]

  • 6. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A, Worek F, Szinicz L, Thiermann H.
    Toxicology; 2007 Apr 20; 233(1-3):166-72. PubMed ID: 16904809
    [Abstract] [Full Text] [Related]

  • 7. Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: a modified kinetic approach.
    Worek F, Wille T, Aurbek N, Eyer P, Thiermann H.
    Toxicol Appl Pharmacol; 2010 Dec 15; 249(3):231-7. PubMed ID: 20888357
    [Abstract] [Full Text] [Related]

  • 8. In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions.
    Kuca K, Cabal J, Jun D, Kassa J, Bartosová L, Kunesová G.
    J Appl Toxicol; 2005 Dec 15; 25(4):296-300. PubMed ID: 16025528
    [Abstract] [Full Text] [Related]

  • 9. Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
    Shih TM, Skovira JW, McDonough JH.
    Arch Toxicol; 2009 Dec 15; 83(12):1083-9. PubMed ID: 19763542
    [Abstract] [Full Text] [Related]

  • 10. Equipotent cholinesterase reactivation in vitro by the nerve agent antidotes HI 6 dichloride and HI 6 dimethanesulfonate.
    Krummer S, Thiermann H, Worek F, Eyer P.
    Arch Toxicol; 2002 Oct 15; 76(10):589-95. PubMed ID: 12373455
    [Abstract] [Full Text] [Related]

  • 11. In vivo cholinesterase inhibitory specificity of organophosphorus nerve agents.
    Shih TM, Kan RK, McDonough JH.
    Chem Biol Interact; 2005 Dec 15; 157-158():293-303. PubMed ID: 16256093
    [Abstract] [Full Text] [Related]

  • 12. A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats.
    Kassa J, Jun D, Karasova J, Bajgar J, Kuca K.
    Chem Biol Interact; 2008 Sep 25; 175(1-3):425-7. PubMed ID: 18547554
    [Abstract] [Full Text] [Related]

  • 13. A comparison of reactivating and therapeutic efficacy of newly-developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
    Kassa J, Karasova JZ, Musilek K, Kuca K.
    Toxicol Mech Methods; 2009 Jun 25; 19(5):346-50. PubMed ID: 19778210
    [Abstract] [Full Text] [Related]

  • 14. Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase.
    Kuca K, Musilek K, Jun D, Pohanka M, Ghosh KK, Hrabinova M.
    J Enzyme Inhib Med Chem; 2010 Aug 25; 25(4):509-12. PubMed ID: 20192902
    [Abstract] [Full Text] [Related]

  • 15. An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes.
    Luo C, Tong M, Chilukuri N, Brecht K, Maxwell DM, Saxena A.
    Biochemistry; 2007 Oct 23; 46(42):11771-9. PubMed ID: 17900152
    [Abstract] [Full Text] [Related]

  • 16. A comparison of the potency of the oxime HLö-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinová M.
    Acta Medica (Hradec Kralove); 2005 Oct 23; 48(2):81-6. PubMed ID: 16259317
    [Abstract] [Full Text] [Related]

  • 17. Mechanism for potent reactivation ability of H oximes analyzed by reactivation kinetic studies with cholinesterases from different species.
    Luo C, Chambers C, Yang Y, Saxena A.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):185-90. PubMed ID: 20096273
    [Abstract] [Full Text] [Related]

  • 18. A structure-activity analysis of the variation in oxime efficacy against nerve agents.
    Maxwell DM, Koplovitz I, Worek F, Sweeney RE.
    Toxicol Appl Pharmacol; 2008 Sep 01; 231(2):157-64. PubMed ID: 18508103
    [Abstract] [Full Text] [Related]

  • 19. Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase.
    Aurbek N, Thiermann H, Szinicz L, Eyer P, Worek F.
    Toxicology; 2006 Jul 05; 224(1-2):91-9. PubMed ID: 16720069
    [Abstract] [Full Text] [Related]

  • 20. In vivo oxime administration does not influence Ellman acetylcholinesterase assay results.
    Guarisco JA, O'Donnell JC, Skovira JW, McDonough JH, Shih TM.
    Toxicol Mech Methods; 2009 Sep 05; 19(6-7):379-85. PubMed ID: 19778238
    [Abstract] [Full Text] [Related]

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