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Journal Abstract Search

316 related items for PubMed ID: 19782152

  • 1. Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives.
    Menendez JA.
    Biochim Biophys Acta; 2010 Mar; 1801(3):381-91. PubMed ID: 19782152
    [Abstract] [Full Text] [Related]

  • 2. Why does tumor-associated fatty acid synthase (oncogenic antigen-519) ignore dietary fatty acids?
    Menendez JA, Colomer R, Lupu R.
    Med Hypotheses; 2005 Mar; 64(2):342-9. PubMed ID: 15607569
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.
    Vazquez-Martin A, Colomer R, Brunet J, Lupu R, Menendez JA.
    Cell Prolif; 2008 Feb; 41(1):59-85. PubMed ID: 18211286
    [Abstract] [Full Text] [Related]

  • 4. The mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells.
    Vazquez-Martin A, Corominas-Faja B, Cufi S, Vellon L, Oliveras-Ferraros C, Menendez OJ, Joven J, Lupu R, Menendez JA.
    Cell Cycle; 2013 Jan 15; 12(2):207-18. PubMed ID: 23287468
    [Abstract] [Full Text] [Related]

  • 5. Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids.
    Zaidi N, Lupien L, Kuemmerle NB, Kinlaw WB, Swinnen JV, Smans K.
    Prog Lipid Res; 2013 Oct 15; 52(4):585-9. PubMed ID: 24001676
    [Abstract] [Full Text] [Related]

  • 6. Increased lipogenesis in cancer cells: new players, novel targets.
    Swinnen JV, Brusselmans K, Verhoeven G.
    Curr Opin Clin Nutr Metab Care; 2006 Jul 15; 9(4):358-65. PubMed ID: 16778563
    [Abstract] [Full Text] [Related]

  • 7. Mediterranean dietary traditions for the molecular treatment of human cancer: anti-oncogenic actions of the main olive oil's monounsaturated fatty acid oleic acid (18:1n-9).
    Menendez JA, Lupu R.
    Curr Pharm Biotechnol; 2006 Dec 15; 7(6):495-502. PubMed ID: 17168666
    [Abstract] [Full Text] [Related]

  • 8. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
    Menendez JA, Ropero S, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Jun 15; 24(6):1369-83. PubMed ID: 15138577
    [Abstract] [Full Text] [Related]

  • 9. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 15; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
    Menendez JA, Colomer R, Lupu R.
    Med Hypotheses; 2005 Mar 15; 64(2):337-41. PubMed ID: 15607568
    [Abstract] [Full Text] [Related]

  • 11. Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity.
    Lodhi IJ, Yin L, Jensen-Urstad AP, Funai K, Coleman T, Baird JH, El Ramahi MK, Razani B, Song H, Fu-Hsu F, Turk J, Semenkovich CF.
    Cell Metab; 2012 Aug 08; 16(2):189-201. PubMed ID: 22863804
    [Abstract] [Full Text] [Related]

  • 12. Peroxisome proliferator-activated receptor-gamma protects ERBB2-positive breast cancer cells from palmitate toxicity.
    Kourtidis A, Srinivasaiah R, Carkner RD, Brosnan MJ, Conklin DS.
    Breast Cancer Res; 2009 Aug 08; 11(2):R16. PubMed ID: 19298655
    [Abstract] [Full Text] [Related]

  • 13. Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer.
    Tomek K, Wagner R, Varga F, Singer CF, Karlic H, Grunt TW.
    Mol Cancer Res; 2011 Dec 08; 9(12):1767-79. PubMed ID: 21970855
    [Abstract] [Full Text] [Related]

  • 14. Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.
    Corominas-Faja B, Vellon L, Cuyàs E, Buxó M, Martin-Castillo B, Serra D, García J, Lupu R, Menendez JA.
    Histol Histopathol; 2017 Jul 08; 32(7):687-698. PubMed ID: 27714708
    [Abstract] [Full Text] [Related]

  • 15. Intermittent Hypoxia Stimulates Lipolysis, But Inhibits Differentiation and De Novo Lipogenesis in 3T3-L1 Cells.
    Musutova M, Weiszenstein M, Koc M, Polak J.
    Metab Syndr Relat Disord; 2020 Apr 08; 18(3):146-153. PubMed ID: 31928504
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?
    Lupu R, Menendez JA.
    Curr Pharm Biotechnol; 2006 Dec 08; 7(6):483-93. PubMed ID: 17168665
    [Abstract] [Full Text] [Related]

  • 17. Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.
    Menendez JA, Vellon L, Oza BP, Lupu R.
    J Cell Biochem; 2005 Apr 01; 94(5):857-63. PubMed ID: 15669079
    [Abstract] [Full Text] [Related]

  • 18. Fatty Acids and Breast Cancer: Make Them on Site or Have Them Delivered.
    Kinlaw WB, Baures PW, Lupien LE, Davis WL, Kuemmerle NB.
    J Cell Physiol; 2016 Oct 01; 231(10):2128-41. PubMed ID: 26844415
    [Abstract] [Full Text] [Related]

  • 19. Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity.
    Hopperton KE, Duncan RE, Bazinet RP, Archer MC.
    Exp Cell Res; 2014 Jan 15; 320(2):302-10. PubMed ID: 24200503
    [Abstract] [Full Text] [Related]

  • 20. Targeting fatty acid synthase-driven lipid rafts: a novel strategy to overcome trastuzumab resistance in breast cancer cells.
    Menendez JA, Vellon L, Lupu R.
    Med Hypotheses; 2005 Jan 15; 64(5):997-1001. PubMed ID: 15780499
    [Abstract] [Full Text] [Related]

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