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451 related items for PubMed ID: 19788733

  • 1. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.
    Roscioni SS, Kistemaker LE, Menzen MH, Elzinga CR, Gosens R, Halayko AJ, Meurs H, Schmidt M.
    Respir Res; 2009 Sep 29; 10(1):88. PubMed ID: 19788733
    [Abstract] [Full Text] [Related]

  • 2. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
    Herfindal L, Nygaard G, Kopperud R, Krakstad C, Døskeland SO, Selheim F.
    Biochem Biophys Res Commun; 2013 Aug 09; 437(4):603-8. PubMed ID: 23850619
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  • 4. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
    Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG.
    Am J Physiol Endocrinol Metab; 2010 Mar 09; 298(3):E622-33. PubMed ID: 20009023
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  • 5. Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A.
    Yokoyama U, Minamisawa S, Quan H, Akaike T, Suzuki S, Jin M, Jiao Q, Watanabe M, Otsu K, Iwasaki S, Nishimaki S, Sato M, Ishikawa Y.
    J Biol Chem; 2008 Oct 17; 283(42):28702-9. PubMed ID: 18697745
    [Abstract] [Full Text] [Related]

  • 6. Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease.
    Oldenburger A, Roscioni SS, Jansen E, Menzen MH, Halayko AJ, Timens W, Meurs H, Maarsingh H, Schmidt M.
    PLoS One; 2012 Oct 17; 7(2):e31574. PubMed ID: 22363678
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  • 9. Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration.
    Yokoyama U, Minamisawa S, Quan H, Akaike T, Jin M, Otsu K, Ulucan C, Wang X, Baljinnyam E, Takaoka M, Sata M, Ishikawa Y.
    Am J Physiol Heart Circ Physiol; 2008 Oct 17; 295(4):H1547-55. PubMed ID: 18689492
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  • 10. The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity.
    Zieba BJ, Artamonov MV, Jin L, Momotani K, Ho R, Franke AS, Neppl RL, Stevenson AS, Khromov AS, Chrzanowska-Wodnicka M, Somlyo AV.
    J Biol Chem; 2011 May 13; 286(19):16681-92. PubMed ID: 21454546
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  • 11. Modulation of cytokine production by cyclic adenosine monophosphate analogs in human leukocytes.
    Gerlo S, Verdood P, Kooijman R.
    J Interferon Cytokine Res; 2010 Dec 13; 30(12):883-91. PubMed ID: 20586615
    [Abstract] [Full Text] [Related]

  • 12. Exchange protein directly activated by cAMP (Epac) protects against airway inflammation and airway remodeling in asthmatic mice.
    Chen YF, Huang G, Wang YM, Cheng M, Zhu FF, Zhong JN, Gao YD.
    Respir Res; 2019 Dec 18; 20(1):285. PubMed ID: 31852500
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  • 13. cAMP induces adhesion of microvascular smooth muscle cells to fibronectin via an Epac-mediated but PKA-independent mechanism.
    Eid AH.
    Cell Physiol Biochem; 2012 Dec 18; 30(1):247-58. PubMed ID: 22759971
    [Abstract] [Full Text] [Related]

  • 14. EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.
    Yang Y, Yang F, Wu X, Lv X, Li J.
    Can J Physiol Pharmacol; 2016 May 18; 94(5):498-507. PubMed ID: 26854595
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  • 15. Rap1 activation plays a regulatory role in pancreatic amylase secretion.
    Sabbatini ME, Chen X, Ernst SA, Williams JA.
    J Biol Chem; 2008 Aug 29; 283(35):23884-94. PubMed ID: 18577515
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  • 16. Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation.
    Wang Z, Dillon TJ, Pokala V, Mishra S, Labudda K, Hunter B, Stork PJ.
    Mol Cell Biol; 2006 Mar 29; 26(6):2130-45. PubMed ID: 16507992
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  • 17. Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle.
    Roscioni SS, Prins AG, Elzinga CR, Menzen MH, Dekkers BG, Halayko AJ, Meurs H, Maarsingh H, Schmidt M.
    Br J Pharmacol; 2011 Oct 29; 164(3):958-69. PubMed ID: 21426315
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  • 18. cAMP signaling through protein kinase A and Epac2 induces substance P release in the rat spinal cord.
    Chen W, McRoberts JA, Ennes HS, Marvizon JC.
    Neuropharmacology; 2021 May 15; 189():108533. PubMed ID: 33744339
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  • 19. The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages.
    Misra UK, Kaczowka S, Pizzo SV.
    Cell Signal; 2008 Aug 15; 20(8):1459-70. PubMed ID: 18495429
    [Abstract] [Full Text] [Related]

  • 20. Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1.
    Huang SK, Wettlaufer SH, Chung J, Peters-Golden M.
    Am J Respir Cell Mol Biol; 2008 Oct 15; 39(4):482-9. PubMed ID: 18421013
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