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Journal Abstract Search

158 related items for PubMed ID: 19791807

  • 1. Evaluation of spirocyclic 3-(3-fluoropropyl)-2-benzofurans as sigma1 receptor ligands for neuroimaging with positron emission tomography.
    Maestrup EG, Fischer S, Wiese C, Schepmann D, Hiller A, Deuther-Conrad W, Steinbach J, Wünsch B, Brust P.
    J Med Chem; 2009 Oct 08; 52(19):6062-72. PubMed ID: 19791807
    [Abstract] [Full Text] [Related]

  • 2. Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine.
    Fischer S, Wiese C, Maestrup EG, Hiller A, Deuther-Conrad W, Scheunemann M, Schepmann D, Steinbach J, Wünsch B, Brust P.
    Eur J Nucl Med Mol Imaging; 2011 Mar 08; 38(3):540-51. PubMed ID: 21072511
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of novel (18)F-labeled spirocyclic piperidine derivatives as σ1 receptor ligands for positron emission tomography imaging.
    Li Y, Wang X, Zhang J, Deuther-Conrad W, Xie F, Zhang X, Liu J, Qiao J, Cui M, Steinbach J, Brust P, Liu B, Jia H.
    J Med Chem; 2013 May 09; 56(9):3478-91. PubMed ID: 23566245
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent.
    Chen YY, Wang X, Zhang JM, Deuther-Conrad W, Zhang XJ, Huang Y, Li Y, Ye JJ, Cui MC, Steinbach J, Brust P, Liu BL, Jia HM.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5270-8. PubMed ID: 25189691
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for central σ1 receptors and comparison with fluoroalkyl homologs.
    Maisonial A, Grosse Maestrup E, Wiese C, Hiller A, Schepmann D, Fischer S, Deuther-Conrad W, Steinbach J, Brust P, Wünsch B.
    Bioorg Med Chem; 2012 Jan 01; 20(1):257-69. PubMed ID: 22136765
    [Abstract] [Full Text] [Related]

  • 6. A ¹⁸F-labeled fluorobutyl-substituted spirocyclic piperidine derivative as a selective radioligand for PET Imaging of sigma₁ receptors.
    Maisonial A, Grosse Maestrup E, Fischer S, Hiller A, Scheunemann M, Wiese C, Schepmann D, Steinbach J, Deuther-Conrad W, Wünsch B, Brust P.
    ChemMedChem; 2011 Aug 01; 6(8):1401-10. PubMed ID: 21618432
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agent.
    Moussa IA, Banister SD, Giboureau N, Meikle SR, Kassiou M.
    Bioorg Med Chem Lett; 2011 Nov 15; 21(22):6820-3. PubMed ID: 21962578
    [Abstract] [Full Text] [Related]

  • 8. In vivo evaluation in rats of [(18)F]1-(2-fluoroethyl)-4-[(4-cyanophenoxy)methyl]piperidine as a potential radiotracer for PET assessment of CNS sigma-1 receptors.
    Waterhouse RN, Chang RC, Zhao J, Carambot PE.
    Nucl Med Biol; 2006 Feb 15; 33(2):211-5. PubMed ID: 16546675
    [Abstract] [Full Text] [Related]

  • 9. Enantioselective σ1 receptor binding and biotransformation of the spirocyclic PET tracer 1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofuran-1,4'-piperidine].
    Wiese C, Grosse Maestrup E, Schepmann D, Grimme S, Humpf HU, Brust P, Wünsch B.
    Chirality; 2011 Feb 15; 23(2):148-54. PubMed ID: 20845431
    [Abstract] [Full Text] [Related]

  • 10. Distinctive in vivo kinetics of the new σ1 receptor ligands (R)-(+)- and (S)-(-)-18F-fluspidine in porcine brain.
    Brust P, Deuther-Conrad W, Becker G, Patt M, Donat CK, Stittsworth S, Fischer S, Hiller A, Wenzel B, Dukic-Stefanovic S, Hesse S, Steinbach J, Wünsch B, Lever SZ, Sabri O.
    J Nucl Med; 2014 Oct 15; 55(10):1730-6. PubMed ID: 25071097
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of [18F]fluoroethyl SA4503 as a PET ligand for the sigma receptor.
    Elsinga PH, Kawamura K, Kobayashi T, Tsukada H, Senda M, Vaalburg W, Ishiwata K.
    Synapse; 2002 Mar 15; 43(4):259-67. PubMed ID: 11835521
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands.
    Moussa IA, Banister SD, Beinat C, Giboureau N, Reynolds AJ, Kassiou M.
    J Med Chem; 2010 Aug 26; 53(16):6228-39. PubMed ID: 20662542
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of fluorine-18-labeled SA4503 as a selective sigma1 receptor ligand for positron emission tomography.
    Kawamura K, Tsukada H, Shiba K, Tsuji C, Harada N, Kimura Y, Ishiwata K.
    Nucl Med Biol; 2007 Jul 26; 34(5):571-7. PubMed ID: 17591557
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of ¹⁸F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging.
    Wang X, Li Y, Deuther-Conrad W, Xie F, Chen X, Cui MC, Zhang XJ, Zhang JM, Steinbach J, Brust P, Liu BL, Jia HM.
    Bioorg Med Chem; 2013 Jan 01; 21(1):215-22. PubMed ID: 23199475
    [Abstract] [Full Text] [Related]

  • 15. Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging.
    Yang D, Comeau A, Bowen WD, Mach RH, Ross BD, Hong H, Van Dort ME.
    Mol Pharm; 2017 Mar 06; 14(3):770-780. PubMed ID: 28135101
    [Abstract] [Full Text] [Related]

  • 16. Automation of the radiosynthesis and purification procedures for [18F]Fluspidine preparation, a new radiotracer for clinical investigations in PET imaging of σ(1) receptors in brain.
    Maisonial-Besset A, Funke U, Wenzel B, Fischer S, Holl K, Wünsch B, Steinbach J, Brust P.
    Appl Radiat Isot; 2014 Feb 06; 84():1-7. PubMed ID: 24291352
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging.
    Selivanova SV, Toscano A, Abate C, Berardi F, Müller A, Krämer SD, Schibli R, Ametamey SM.
    Nucl Med Biol; 2015 Apr 06; 42(4):399-405. PubMed ID: 25637276
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and in vivo evaluation of [11C]SA6298 as a PET sigma1 receptor ligand.
    Kawamura K, Ishiwata K, Tajima H, Ishii S, Shimada Y, Matsuno K, Homma Y, Senda M.
    Nucl Med Biol; 1999 Nov 06; 26(8):915-22. PubMed ID: 10708305
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of a (18) F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging.
    Ye J, Wang X, Deuther-Conrad W, Zhang J, Li J, Zhang X, Wang L, Steinbach J, Brust P, Jia H.
    J Labelled Comp Radiopharm; 2016 Jul 06; 59(9):332-9. PubMed ID: 27277387
    [Abstract] [Full Text] [Related]

  • 20. Fluorinated PET Tracers for Molecular Imaging of σ1 Receptors in the Central Nervous System.
    Weber F, Brust P, Laurini E, Pricl S, Wünsch B.
    Adv Exp Med Biol; 2017 Jul 06; 964():31-48. PubMed ID: 28315263
    [Abstract] [Full Text] [Related]

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